Clinical trial Recruiting at 1 site Interventional Ages 25 to 40 Men only

Ashwagandha with resistance training to boost strength and stress markers

Official title: The Impact of 12-week Ashwagandha Supplementation Induced by Resistance Training on Strength, Levels of Neurotrophic and Stress Response Proteins, Oxidative and Psychological Stress, and Cognitive Function in Physically Active Male Adults

Run by Gdansk University of Physical Education and Sport · NCT07803068 · Data updated 2026-11-12

This 12-week study tests whether taking ASHWAGANDHA along with regular resistance training helps healthy, trained men see improvements in strength, stress levels, sleep, and cognitive function compared with a placebo.

More Strength Training Adaptations trials

Quick facts

Study typeInterventional
Ages25 Years to 40 Years
SexMen only
Enrollment40 (estimated)
SponsorGdansk University of Physical Education and Sport
Academic / other
Locations1 site (Gdansk, Pomeranian Voivodeship)
StatusRecruiting
StartedSeptember 1, 2025
Main results expectedMarch 2027
Study endsSeptember 2027
Registry record updatedSeptember 3, 2026
Trial IDNCT07803068 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy, non-smoking men 25–40 with at least 6 months of resistance training experience and no use of Ashwagandha or adaptogenic supplements.

Probably not a fit

Individuals who do not respond to Ashwagandha or who do not benefit from resistance training may see little to no additional benefit beyond placebo.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study is a randomized, double-blind, placebo-controlled trial in healthy, resistance-trained men aged 25–40. Participants will take either Ashwagandha or a placebo daily for 12 weeks while performing resistance training three times per week. Outcomes include muscle strength, sleep quality, cognitive function, and a range of hormonal, neurotrophic, and oxidative stress markers measured before and after the intervention. The goal is to see if Ashwagandha enhances exercise adaptations and overall well-being in this population.

Why it matters

Potential benefit: If successful, the intervention could support improved strength, stress resilience, sleep, and cognitive performance in physically active men.

How similar studies have gone: Previous studies suggest potential benefits of Ashwagandha for stress and performance, but evidence is limited and methodologically varied in physically active individuals; this study adds rigorous design in a trained population.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Minimum 6 months of consistent resistance training experience
* Participation in at least two resistance training sessions per week
* No use of Ashwagandha, adaptogenic supplements, or medications
* No medical contraindications and signed informed consent

Exclusion Criteria:

* History of cardiovascular events, liver disorders, or psychiatric illness
* Medical contraindications for participation
* Use of nicotine products, including e-cigarettes
* BMI \> 29.9, to ensure homogeneity in body composition

Where it's running

  • Gdansk University of Physical Education and Sport
    Gdansk, Pomeranian Voivodeship, Poland
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.