Clinical trial Recruiting at 2 sites Interventional Ages 5 and up

Home ventilation and air cleaner for asthma in low-income DFW homes

Official title: Energy Recovery Ventilation and Air Cleaner Interventions to Improve Indoor Air Quality, Mold Control, and Asthma-Related Health Outcomes Among Inner-City Children and Adults in Low-Income Households

Run by The University of Texas at Arlington · NCT07196436 · Data updated 2026-11-12

This trial will test whether installing whole-home energy recovery ventilators or portable air cleaners in low-income Dallas–Fort Worth homes lowers indoor pollutants and improves asthma symptoms and quality of life over one year.

More Sleep Quality trials

Quick facts

Study typeInterventional
Ages5 Years and up
SexAll
Enrollment80 (estimated)
SponsorThe University of Texas at Arlington
Academic / other
Locations2 sites (Arlington, Texas and 1 other locations)
StatusRecruiting
StartedOctober 10, 2025
Main results expectedJanuary 31, 2028
Study endsFebruary 28, 2028
Registry record updatedOctober 29, 2025
Trial IDNCT07196436 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal participants are homeowners in the Dallas–Fort Worth area with physician-diagnosed asthma (children aged ≥5 and adults), from low-income households applying for home retrofit assistance, living in non-smoking homes.

Probably not a fit

People who live with smokers, renters or those outside the Dallas–Fort Worth area, and patients whose asthma is driven mainly by outdoor or non-indoor triggers may not receive benefit from these home-based interventions.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This double-blind, placebo-controlled, four-arm randomized trial will enroll 80 households (at least 40 children and 40 adults with physician-diagnosed asthma) from low-income applicants to a home retrofit program in the Dallas–Fort Worth area. After a one-year observation period, households will be randomized to receive an active energy recovery ventilator (ERV with MERV-13 filter), a sham ERV (recirculation only), an active portable air cleaner (PAC with HEPA and carbon filters), or a sham PAC (filters removed) for one year. Indoor air pollution and mold levels, housing conditions, and asthma-related clinical outcomes (control, lung function, sleep, stress, and quality of life) will be measured, and cost-benefit analyses and protocol evaluations for practical indoor air quality monitoring will be performed. All participants and field staff will be blinded to whether the installed devices are active or sham.

Why it matters

Potential benefit: If effective, these home-based ventilation or filtration interventions could reduce indoor pollutant and mold exposure and improve asthma control, lung function, and quality of life for low-income families.

How similar studies have gone: Prior smaller trials and observational studies have shown that HEPA filtration and improved ventilation can reduce indoor particulate levels and sometimes improve asthma symptoms, but long-term, double-blind randomized evidence in low-income urban households is limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals with physician-diagnosed asthma, including both adults and children aged 5-17
* Homeowners living in the DFW metropolitan area, TX

Exclusion Criteria:

* Participants living in homes with any smokers

Where it's running

  • University of Texas at Arlington
    Arlington, Texas, United States
    Recruiting
  • Rebuilding Together North Texas
    Plano, Texas, United States
    Recruiting

Study contacts

  • Principal investigator: Insung Kang, Ph.D. — The University of Texas at Arlington
  • Study coordinator: Insung Kang, Ph.D.
  • Email: insung.kang@uta.edu
  • Phone: 817-272-2167

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.