Digital and Plasma Biomarkers for Delirium in the ICU

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study monitors older ICU patients to see if wearable digital data and plasma biomarkers relate to delirium. Participants will wear a device to continuously collect biometric information and provide serial blood samples during their ICU stay, with daily delirium assessments by study staff. The goal is to see if these biomarkers can help detect, predict, or prognosticate delirium in the ICU setting. The study is conducted at Scripps Health facilities and recruits adults admitted to the ICU who can consent or have a representative consent. It excludes patients with advanced dementia, liver failure requiring replacement therapy, renal replacement therapy, or significant structural brain injuries.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Admitted to the intensive care unit
* Able to consent or have a legally authorized representative consent on their behalf
* English speaker
* Expected ICU stay of 48 hours or more

Exclusion Criteria:

* Advanced dementia
* End stage liver disease
* Renal replacement therapy
* Structural brain injury, including but not limited to traumatic brain injury, cerebrovascular accident and intracranial hemorrhage,

Where it's running

• Scripps Memorial La Jolla Hospital
  San Diego, California, United States Recruiting
• Scripps Green Hospital
  La Jolla, California, United States Not yet recruiting

Study contacts

• Study coordinator: Stuti Jaiswal, MD, PhD
• Email: jaiswal.stuti@scrippshealth.org
• Phone: 858-554-9100

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.