Clinical trial Recruiting at 1 site Interventional Ages 50 and up

Acupoint Stimulation and Exercise for Pre-frail Older Adults in Taiwan

Official title: Exploring the Associations Among Frailty, Daily Physical Activity, Sleep, and Traditional Chinese Medicine Constitution in Taiwanese Older Adults, and Evaluating the Effects of Acupoint Stimulation Interventions

Run by Tainan Hospital, Ministry of Health and Welfare · NCT07732530 · Data updated 2026-11-12

This study tests whether combining exercise with daytime and sleep-improving acupoint stimulation helps pre-frail adults 50 and older in Taiwan feel less frail and sleep better.

More Aging trials

Quick facts

Study typeInterventional
Ages50 Years and up
SexAll
Enrollment30 (estimated)
SponsorTainan Hospital, Ministry of Health and Welfare
Academic / other
Locations1 site (Tainan)
StatusRecruiting
StartedJune 3, 2025
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedAugust 7, 2026
Trial IDNCT07732530 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 50+ who are pre-frail (frailty score 1-2) and able to participate in exercise and wear an actigraph.

Probably not a fit

Individuals who cannot wear an actigraph or fully participate in physical assessments may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized trial, pre-frail older adults in Taiwan will be assigned to either a Vivifrail exercise program alone or the same exercise plus acupoint stimulation aimed at daytime wakefulness and sleep. The study will measure frailty severity, sleep quality, and daily physical functioning to see if the combined approach offers added benefits. Participants will keep a 7-day sleep diary and complete questionnaires, with actigraphy used to monitor activity and sleep. The trial explores how non-pharmacologic, non-invasive strategies may address frailty and sleep in aging populations. Results could inform integrated lifestyle interventions for pre-frail individuals.

Why it matters

Potential benefit: If successful, the combined treatment could offer a non-invasive way to reduce frailty and improve sleep and daily function in older adults.

How similar studies have gone: Similar non-pharmacologic programs for frailty and sleep have shown promise, but this exact combination with acupoint stimulation is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Individuals who are capable of undergoing frailty assessments.
2. Individuals who possess effective communication skills.
3. Aged 50 years or older.
4. Willing to provide written informed consent, keep a 7-day sleep diary, and complete related questionnaires.
5. Identified as pre-frail (frailty score of 1-2 points) according to the frailty phenotype criteria for the clinical trial phase.

Exclusion Criteria:

1\. Individuals who are unwilling or unable to wear an actigraph (wrist monitor) or undergo physical measurements.

Where it's running

  • Tainan Hospital, Ministry of Health and Welfare
    Tainan, Taiwan
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.