Investigating the link between sleep quality and Alzheimer's disease in older Mexican Americans and Non-Hispanic Whites
Sleep Quality and Mechanistic Links to Alzheimer Disease and Related Disorders among older Mexican Americans and Non-Hispanic Whites
This study is looking at how the quality of sleep might influence the chances of older Mexican Americans and Non-Hispanic Whites developing Alzheimer's and similar conditions, hoping to find ways to improve sleep and help protect brain health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10653856 on NIH RePORTER |
What this research studies
This research explores how sleep quality affects the risk of developing Alzheimer's Disease and related disorders among older Mexican Americans and Non-Hispanic Whites. It aims to identify both subjective and objective measures of sleep quality and their association with cognitive impairment. By leveraging an existing study on aging in Latino elders, the research will involve 1,000 participants to uncover the mechanisms linking sleep issues to cognitive decline. The findings could lead to targeted interventions for improving sleep and potentially reducing the risk of Alzheimer's.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly Mexican Americans and Non-Hispanic Whites, who may be experiencing cognitive impairment or sleep disorders.
Not a fit: Patients who are younger than 50 or do not have concerns related to sleep quality or cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing Alzheimer's disease through better sleep management.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between sleep quality and cognitive decline, indicating that this approach is both relevant and potentially impactful.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Yaffe, Kristine — University of California, San Francisco
- Study coordinator: Yaffe, Kristine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.