Condition

Rheumatic Diseases clinical trials and research

• 16Clinical trials
• 12NIH research projects
• 11Countries

Newest Rheumatic Diseases clinical trials

All recruiting trials (16)

• Combined e-Learning and Virtual Reality Training to Improve Rheumatology Provider Communication

  This trial tests whether a combined online course and VR training helps rheumatology providers communicate better with patients and whether patients rate their communication more highly after training.

  Recruiting Leiden University Medical Center · Leiden, South Holland · NCT07835256

• Pain patterns in rheumatic diseases: see if pain works differently in patients and healthy people

  This observational study tests how pain is experienced and measured in people with rheumatic diseases compared with healthy volunteers.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07829497

• Screening for lipid disorders in children and teens with chronic diseases to flag cardiovascular risk

  This study tests a blood test and a questionnaire to screen children and teens with chronic conditions for lipid metabolism disorders and familial hyperlipidemia.

  Recruiting Jena University Hospital · Jena · NCT07716488

• Anti-CD19/BCMA CAR‑NK cell therapy for refractory pediatric rheumatic diseases

  This trial will test a single injection of engineered CAR‑NK cells aimed at CD19 and BCMA to see if it is safe and helps children aged 5 and older whose rheumatic diseases have not responded to other treatments.

  Recruiting Early Phase 1 The Children's Hospital of Zhejiang University School of Medicine · Hangzhou, Zhejiang · NCT07490041

• Measuring how steroids affect children and young people with rheumatic conditions

  This project will create a questionnaire, using interviews with children, young people and their parents, to measure how steroids affect kids with rheumatic conditions.

  Recruiting at 3 sites University of the West of England · Bristol, North Somerset and 2 other locations · NCT07350395

• Reducing unnecessary medications in older adults with rheumatic conditions

  This project will test whether giving doctors individualized MedSafer reports plus patient EMPOWER brochures helps people 60+ with rheumatic conditions who take five or more regular medications stop or reduce risky medicines.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07278609

• Pain neuroscience education and vagal nerve stimulation to help people with rheumatoid arthritis

  This study tests whether pain neuroscience education, vagal nerve stimulation, or a standard exercise program can improve pain, function, and quality of life for adults with rheumatoid arthritis.

  Recruiting Medipol University · Istanbul, Fatih · NCT07274124

• Personalized lab test to predict the best treatment for rheumatic diseases

  This project tests a lab-based cell assay to see if it can predict which DMARD will work best for adults with autoimmune rheumatic diseases such as RA, PsA, axSpA, and GCA.

  Recruiting University of Bonn · Bonn, North Rhine-Westphalia · NCT07150000

• Cognitive behavioral therapy for long-term pain in rheumatic diseases

  This study is testing whether cognitive behavioral therapy can help people with long-term pain from rheumatic diseases manage their pain better.

  Recruiting Diakonhjemmet Hospital · Oslo, Oslo · NCT06413914

• Evaluating Fertility Treatments in Women with Rheumatic Diseases

  This study is trying to see how well fertility treatments work for women with rheumatic diseases and if these treatments affect their health conditions.

  Recruiting IRCCS San Raffaele · Milan · NCT05807256

• Evaluating placental markers in pregnant women with and without antiphospholipid syndrome

  This study is trying to see if certain markers in the blood can help predict the risk of preeclampsia in pregnant women with antiphospholipid syndrome compared to those without it.

  Recruiting IRCCS San Raffaele · Milan · NCT05786235

• Using brain stimulation to help COVID-19 patients with autoimmune diseases

  This study is testing if a type of brain stimulation can help COVID-19 patients with autoimmune diseases feel better by reducing their fatigue and pain.

  Recruiting University of Sao Paulo · São Paulo · NCT04890483

• Mood changes during TNF-alpha blocker treatment for chronic inflammatory rheumatic diseases

  This will test whether starting TNF-alpha blocker treatment improves anxiety or depression symptoms in adults with rheumatoid arthritis, spondyloarthritis, ankylosing spondylitis, or psoriatic arthritis.

  Recruiting Centre Hospitalier Universitaire de Besancon · Besançon · NCT04817072

• Registry and biorepository for rheumatic diseases

  This study is collecting samples and health information from adults with rheumatic diseases at Yale clinics to help researchers learn more about these conditions and improve future treatments.

  Recruiting Yale University · New Haven, Connecticut · NCT04402086

• Observational research on chronic diseases and healthcare analytics

  This study looks at health records to see how well different treatments work for chronic diseases like HIV and hepatitis, aiming to improve patient care and support.

  Recruiting Epividian · Durham, North Carolina · NCT03813862

• Exploring the causes of rheumatic diseases in minority communities

  This study looks at the causes and effects of rheumatic diseases in minority communities to better understand health differences and improve care for those affected.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT00024479

NIH-funded research (12)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Improving COVID-19 Vaccine Uptake Among Racial and Ethnic Minority Groups with Rheumatic Diseases

  A patient-facing program tests a multi-modal approach using storytelling videos and trained patient navigators to help Black and Latinx adults with autoimmune rheumatic diseases get recommended COVID-19 vaccines and boosters.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11371381

• How health policies affect people with systemic autoimmune and rheumatic conditions

  This project looks at how health policies and medical care affect health and pregnancy outcomes for reproductive-age women with systemic autoimmune and rheumatic diseases.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11335678

• Long-term immune and health effects of COVID-19 in people with autoimmune rheumatic diseases

  This project looks at how COVID-19 changes immune responses and causes lingering symptoms in people with autoimmune rheumatic diseases like rheumatoid arthritis and lupus.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11289321

• How health policies impact women with autoimmune diseases during pregnancy

  This study is looking at how health policies affect women with autoimmune and rheumatic diseases during pregnancy, aiming to understand their experiences and access to care, so we can better support their health and treatment options.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11167103

• Training new scientists in rheumatic diseases

  This program is training new scientists to explore the causes and treatments of rheumatic diseases, like arthritis, by working together at the University of Pennsylvania and the Children’s Hospital of Philadelphia, so they can help improve care for patients of all ages.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11094963

• Helping Black and Latinx patients with rheumatic diseases get recommended COVID-19 vaccines

  This project helps Black and Latinx adults living with autoimmune rheumatic diseases get their recommended COVID-19 vaccines.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11061299

• Effects of COVID-19 on patients with autoimmune diseases

  This study is looking at how COVID-19 affects people with autoimmune diseases like rheumatoid arthritis and lupus, to better understand their immune responses and how their treatments might change their reactions to the virus and vaccines, ultimately aiming to improve their health outcomes.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11018582

• Exploring how pain, sleep, and body functions are connected in children with rheumatic diseases

  This study is looking at how pain, sleep, and body responses are connected in children with rheumatic diseases, and it aims to help improve their quality of life by understanding these relationships better.

  NIH research Northwestern University at Chicago · Chicago, United States · NIH-11015019

• Improving health for patients with rheumatic diseases through advanced research and technology.

  This study at Washington University is looking for ways to improve the health of people with rheumatic diseases by understanding how inflammation and autoimmunity work, so they can create personalized treatments that really fit each person's needs.

  NIH research Washington University · Saint Louis, United States · NIH-10925271

• Understanding how to improve pregnancy outcomes for women with rheumatic diseases

  This study is all about helping women with rheumatic diseases feel more confident and informed when deciding about pregnancy by creating a helpful tool called MyVoice, which will provide important information and support in rheumatology clinics.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10916367

• Exploring the connections between disease mechanisms and outcomes in rheumatic diseases.

  This study is all about helping new researchers learn how to better understand and study rheumatic diseases like lupus and fibromyalgia, so they can improve pain management and overall care for patients like you.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10877823

• Exploring environmental factors in childhood autoimmune diseases

  This study is bringing together doctors and researchers to explore how things in our environment might affect kids with autoimmune diseases, like arthritis, so they can find better ways to treat these conditions.

  NIH research Boston Children's Hospital · Boston, United States · NIH-10868992

Related topics

Quick answers

How many Rheumatic Diseases clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (4 trials), Germany (2 trials), Italy (2 trials), Netherlands (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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