Condition

ANCA Associated Vasculitis (AAV) clinical trials and research

• 16Clinical trials
• 1New in 30 days
• 5Countries

Newest ANCA Associated Vasculitis (AAV) clinical trials

All recruiting trials (16)

• Dermal priming to boost flu vaccine response in people on B cell depletion

  This study tests whether applying a topical cream with imiquimod on the skin around vaccination can boost the body’s response to the flu shot in people who are receiving B cell–depleting therapy.

  Recruiting Cambridge University Hospitals NHS Foundation Trust · Cambridge · NCT07925996

• FT839 therapy for autoimmune diseases

  This trial tests FT839, given alone or with rituximab, to see if it is safe and can help people with certain autoimmune diseases who have not responded to other treatments.

  Recruiting Phase 1/2 Fate Therapeutics · Fullerton, California · NCT07800871

• Obinutuzumab beta with low-dose steroids in new-onset ANCA-associated glomerulonephritis

  This study tests whether adding Obinutuzumab beta to a rapid-tapering glucocorticoid plan can help people with new-onset ANCA-associated glomerulonephritis see if they achieve remission.

  Recruiting Phase 2 Chinese PLA General Hospital · Beijing · NCT07746180

• MTS109 treatment for refractory autoimmune diseases

  This trial tests whether MTS109 (an mRNA-LNP given by subcutaneous injection) is safe and tolerable in adults with moderate to severe autoimmune diseases that have not responded to standard treatments.

  Recruiting Early Phase 1 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT07526350

• Dual-target CAR T therapy (CD19 and BCMA) for relapsed or treatment-resistant autoimmune diseases

  This will try a single infusion of off-the-shelf (allogeneic) CAR T-cells that target CD19 and BCMA in adults whose autoimmune disease has relapsed or not responded to other treatments.

  Recruiting Phase 1 Institute of Hematology & Blood Diseases Hospital, China · Tianjin · NCT07315087

• Total-body PET scanning to find disease activity and cardiovascular risk in ANCA-associated vasculitis

  We will test whether whole-body PET scans with FDG, DOTATATE, and FAPI can detect active inflammation and identify people with active ANCA-associated vasculitis who are at higher long-term cardiovascular risk.

  Recruiting University of Edinburgh · Edinburgh · NCT07258524

• BDB-001 for adults with ANCA-associated vasculitis

  This trial will test whether adding the experimental drug BDB-001 to standard induction therapy (cyclophosphamide then azathioprine, or rituximab) helps adults with active ANCA-associated vasculitis achieve remission.

  Recruiting Phase 3 Staidson (Beijing) Biopharmaceuticals Co., Ltd · Beijing, Beijing Municipality and 64 other locations · NCT07168161

• Personalized lab test to predict the best treatment for rheumatic diseases

  This project tests a lab-based cell assay to see if it can predict which DMARD will work best for adults with autoimmune rheumatic diseases such as RA, PsA, axSpA, and GCA.

  Recruiting University of Bonn · Bonn, North Rhine-Westphalia · NCT07150000

• Descartes-08 treatment for children, teens, and young adults with select autoimmune diseases

  This trial will test whether Descartes-08 is safe and can help control disease in children, adolescents, and young adults with childhood-onset lupus, ANCA-associated vasculitis, juvenile myasthenia gravis, or juvenile dermatomyositis.

  Recruiting at 3 sites Phase 1/2 Cartesian Therapeutics · Washington D.C., District of Columbia and 2 other locations · NCT07089121

• Evaluating OL-108 for autoimmune diseases that have not responded to previous treatments

  This study is testing a new treatment called OL-108 to see if it can help people with autoimmune diseases that haven't improved with other therapies.

  Recruiting at 2 sites Phase 1 Beijing GoBroad Hospital · Beijing and 1 other locations · NCT06980597

• CAR T-cell therapy for autoimmune diseases

  This study is testing a new CAR T-cell therapy to see if it can help people with tough autoimmune diseases like lupus and systemic sclerosis feel better.

  Recruiting Phase 1 Institute of Hematology & Blood Diseases Hospital, China · Tianjin · NCT06941129

• Universal CD19-targeting CAR-γδT cell therapy for refractory autoimmune diseases

  This trial will try infusing universal CD19-targeting CAR-γδT cells into adults with refractory B cell–driven autoimmune diseases to see if removing autoreactive B cells improves symptoms.

  Recruiting Phase 1/2 Peking University Third Hospital · Beijing · NCT06828042

• Targeted CAR-T therapy for autoimmune diseases

  This study is testing a new CAR-T cell therapy to see if it can help people with autoimmune diseases like lupus, scleroderma, and multiple sclerosis feel better.

  Recruiting Early Phase 1 Nanjing Bioheng Biotech Co., Ltd. · Lianyungang, Jiangus · NCT06775912

• Investigating the Role of Y Chromosome Mutations in Autoimmune Diseases

  This study is trying to see how changes in the Y chromosome might affect the immune system and contribute to autoimmune diseases like Giant Cell Arteritis and Polymyalgia Rheumatica.

  Recruiting University of Bonn · Bonn, North Rhine-Westphalia · NCT06696027

• Using engineered immune cells to treat difficult autoimmune diseases

  This study is testing if a new type of immune cell treatment can help people with tough autoimmune diseases that haven't responded to other therapies.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT06614270

• Avacopan treatment for ANCA-associated vasculitis

  This study is testing if avacopan, used with a lower dose of steroids and rituximab, can help people with newly diagnosed ANCA-associated vasculitis feel better compared to a longer course of steroids.

  Recruiting at 21 sites Phase 4 Chiba University · Toyoake, Aichi-ken and 21 other locations · NCT06611696

Related topics

Quick answers

How many ANCA Associated Vasculitis (AAV) clinical trials are recruiting right now?

16, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in China (9 trials), United Kingdom (2 trials), Germany (2 trials), United States (2 trials), Japan (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 3, Phase 1: 3, Early Phase 1: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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