Clinical trial Recruiting at 1 site Interventional Ages 6 to 18

Screening for lipid disorders in children and teens with chronic diseases to flag cardiovascular risk

Official title: Screening Auf Lipidstoffwechselstörungen Und familiäre Hyperlipidämien Bei Kindern Und Jugendlichen Mit erhöhtem kardiovaskulären Risiko Durch Chronische Erkrankungen Wie Angeborene Herzfehler, Chronisch entzündliche Darmerkrankungen, Zöliakie Sowie Rheumatische Erkrankungen

Run by Jena University Hospital · NCT07716488 · Data updated 2026-11-12

This study tests a blood test and a questionnaire to screen children and teens with chronic conditions for lipid metabolism disorders and familial hyperlipidemia.

More Congenital Heart Disease trials

Quick facts

Study typeInterventional
Ages6 Years to 18 Years
SexAll
Enrollment600 (estimated)
SponsorJena University Hospital
Academic / other
Locations1 site (Jena)
StatusRecruiting
StartedAugust 1, 2026
Main results expectedJanuary 31, 2027
Study endsApril 30, 2027
Registry record updatedJuly 21, 2026
Trial IDNCT07716488 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are 5–18-year-olds with a chronic condition (e.g., congenital heart disease, IBD, celiac disease, or rheumatic disease) treated at the University Hospital Jena.

Probably not a fit

Patients without a lipid risk or familial lipid disorder identified by screening may not receive direct benefits from the test itself.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial aims to identify lipid metabolism problems early in pediatric patients who have chronic illnesses such as congenital heart disease, inflammatory bowel disease, celiac disease, or rheumatic diseases. It uses a blood test and a questionnaire to screen for risk factors and inherited lipid disorders. Participants are 5 to 18 years old and are treated at the University Hospital Jena’s pediatric clinics. The study seeks to determine how feasible and informative universal lipid screening is in this setting. No treatment or intervention beyond screening is described in the protocol.

Why it matters

Potential benefit: If successful, the screening approach could enable earlier detection and management of lipid disorders to reduce future cardiovascular risk.

How similar studies have gone: Other countries have shown cost-effectiveness and benefits from lipid screening in youth, but this approach is not yet standard in Germany.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria: Patients aged 5 to 18 years who are being treated at the UKJ in one of our specialized pediatric clinics for a chronic condition-such as a congenital heart defect, chronic inflammatory bowel disease, celiac disease, or a rheumatic disease.

Exclusion Criteria: Lack of consent from the patient or legal guardian(s)

Where it's running

  • University Hospital Jena
    Jena, Germany
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.