Screening for lipid disorders in children and teens with chronic diseases to flag cardiovascular risk
Official title: Screening Auf Lipidstoffwechselstörungen Und familiäre Hyperlipidämien Bei Kindern Und Jugendlichen Mit erhöhtem kardiovaskulären Risiko Durch Chronische Erkrankungen Wie Angeborene Herzfehler, Chronisch entzündliche Darmerkrankungen, Zöliakie Sowie Rheumatische Erkrankungen
Run by Jena University Hospital · NCT07716488 · Data updated 2026-11-12
This study tests a blood test and a questionnaire to screen children and teens with chronic conditions for lipid metabolism disorders and familial hyperlipidemia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 6 Years to 18 Years |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Jena University Hospital Academic / other |
| Locations | 1 site (Jena) |
| Status | Recruiting |
| Started | August 1, 2026 |
| Main results expected | January 31, 2027 |
| Study ends | April 30, 2027 |
| Registry record updated | July 21, 2026 |
| Trial ID | NCT07716488 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are 5–18-year-olds with a chronic condition (e.g., congenital heart disease, IBD, celiac disease, or rheumatic disease) treated at the University Hospital Jena.
✕Probably not a fit
Patients without a lipid risk or familial lipid disorder identified by screening may not receive direct benefits from the test itself.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial aims to identify lipid metabolism problems early in pediatric patients who have chronic illnesses such as congenital heart disease, inflammatory bowel disease, celiac disease, or rheumatic diseases. It uses a blood test and a questionnaire to screen for risk factors and inherited lipid disorders. Participants are 5 to 18 years old and are treated at the University Hospital Jena’s pediatric clinics. The study seeks to determine how feasible and informative universal lipid screening is in this setting. No treatment or intervention beyond screening is described in the protocol.
Why it matters
Potential benefit: If successful, the screening approach could enable earlier detection and management of lipid disorders to reduce future cardiovascular risk.
How similar studies have gone: Other countries have shown cost-effectiveness and benefits from lipid screening in youth, but this approach is not yet standard in Germany.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients aged 5 to 18 years who are being treated at the UKJ in one of our specialized pediatric clinics for a chronic condition-such as a congenital heart defect, chronic inflammatory bowel disease, celiac disease, or a rheumatic disease. Exclusion Criteria: Lack of consent from the patient or legal guardian(s)
Where it's running
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University Hospital Jena
Jena, Germany Recruiting
Study contacts
- Principal investigator: Alexandra M Kiess, MD — University Hospital Jena
- Study coordinator: Alexandra M Kiess, MD
- Email: AlexandraMiriam.Kiess@med.uni-jena.de
- Phone: 0049-3641-9329578
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.