Exploring how pain, sleep, and body functions are connected in children with rheumatic diseases
Official title: Mentored Patient-Oriented Research of Novel Mechanisms Linking Pain, Sleep-Wake Patterns, and Autonomic Activity in Rheumatic Diseases
Funded at Northwestern University at Chicago · NIH-11015019 · Data updated 2026-11-12
This study is looking at how pain, sleep, and body responses are connected in children with rheumatic diseases, and it aims to help improve their quality of life by understanding these relationships better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | February 24, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $189,689 |
| NIH project number | 5K24AR080840-03 |
| Project ID | NIH-11015019 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who are diagnosed with rheumatic diseases and experience chronic pain or sleep disturbances.
✕Less likely to help
Patients outside the age range of 0-11 years or those without rheumatic diseases may not benefit from this research.
What this research studies
This research investigates the complex relationships between pain, sleep patterns, and autonomic activity in children suffering from rheumatic diseases. By utilizing advanced monitoring techniques, such as accelerometers, the study aims to gather data on how these factors interact and affect each other. The principal investigator, Dr. Yvonne Lee, will also mentor new researchers in this field, ensuring that innovative approaches to understanding and treating these conditions are developed. The goal is to improve the quality of life for young patients by addressing the underlying mechanisms of their symptoms.
Why it matters
Potential benefit: If successful, this research could lead to better management strategies for pain and sleep issues in children with rheumatic diseases.
How similar studies have gone: Previous research has shown promising results in understanding pain mechanisms in rheumatic diseases, indicating that this approach could yield valuable insights.
Where this research is happening
-
Northwestern University at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Lee, Yvonne Claire — Northwestern University at Chicago
- Study coordinator: Lee, Yvonne Claire
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.