Evaluating Fertility Treatments in Women with Rheumatic Diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the outcomes of assisted reproductive techniques (ARTs) in women diagnosed with systemic rheumatological diseases, such as Systemic Lupus Erythematosus and Anti-Phospholipid Antibody Syndrome. It will analyze the response to ARTs, focusing on the potential reactivation of underlying diseases and the success rates of fertility treatments. The study will collect data on various fertility treatments administered, including ovarian stimulation and embryo transfer procedures, to understand their impact on both fertility and disease management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients diagnosed with systemic immunoreumatologic disease such as SLE, APS, RA, SpA, SclS, SS, PM-DM, vasculitis
* patients who have performed one or more PMAs between January 2000 and April 2021
* patients who had their last follow-up by February 2022

Exclusion Criteria:

* Patients diagnosed with only one organ autoimmunity (e.g., diabetes mellitus I, thyroiditis of Hashimoto's, celiac disease or chronic inflammatory bowel disease in the absence of systemic disease associated);
* patients with severe renal failure, significant pulmonary hypertension or cardiomyopathy severe.

Where it's running

• San Raffaele Hospital
  Milan, Italy Recruiting

Study contacts

• Principal investigator: Patrizia Rovere Querini, PhD, MD — IRCCS Ospedale San Raffaele
• Study coordinator: Patrizia Rovere Querini, PhD, MD
• Email: rovere.patrizia@hsr.it
• Phone: +390226436095

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Evaluating placental markers in pregnant women with and without antiphospholipid syndrome

  This study is trying to see if certain markers in the blood can help predict the risk of preeclampsia in pregnant women with antiphospholipid syndrome compared to those without it.

  Recruiting IRCCS San Raffaele · Milan · NCT05786235

• MOCHA: Inpatient Mental Health Care for High-Risk Pregnancy

  This study tests a collaborative mental health program for pregnant or recently postpartum patients hospitalized for medical problems to see if it can be delivered feasibly and acceptably.

  Recruiting Indiana University · Indianapolis, Indiana · NCT07540585

• Observational study on the safety of relugolix therapy in pregnant women

  This study is trying to see if relugolix therapy is safe for pregnant women and their babies by looking at health outcomes during and after pregnancy.

  Recruiting Sumitomo Pharma Switzerland GmbH · Wilmington, North Carolina · NCT05739123

• Combined e-Learning and Virtual Reality Training to Improve Rheumatology Provider Communication

  This trial tests whether a combined online course and VR training helps rheumatology providers communicate better with patients and whether patients rate their communication more highly after training.

  Recruiting Leiden University Medical Center · Leiden, South Holland · NCT07835256

• Pain patterns in rheumatic diseases: see if pain works differently in patients and healthy people

  This observational study tests how pain is experienced and measured in people with rheumatic diseases compared with healthy volunteers.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07829497

• Two-Door Doulas: Enhanced vs Standard Medicaid Doula Care in Pregnancy

  This trial tests whether an enhanced, earlier, and more frequent doula support program helps pregnant people on Medicaid feel less depression and anxiety after birth compared with the standard Medicaid doula care in Florida.

  Recruiting University of Florida · Gainesville, Florida · NCT07799805

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.