NIH-funded research R01 grant

How health policies affect people with systemic autoimmune and rheumatic conditions

Official title: Effects of health policy on the health of people with systemic autoimmune and rheumatic diseases

Funded at University of Pittsburgh at Pittsburgh · NIH-11335678 · Data updated 2026-11-12

This project looks at how health policies and medical care affect health and pregnancy outcomes for reproductive-age women with systemic autoimmune and rheumatic diseases.

More Rheumatic Diseases research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startMay 25, 2025
Project endFebruary 28, 2030
Funding year2026
Award (this year)$668,861
NIH project number5R01HD118690-02
Project IDNIH-11335678 on NIH RePORTER

Who could benefit from this research

Could help

Reproductive-age women with systemic autoimmune and rheumatic diseases who are pregnant, planning pregnancy, postpartum, or have prior pregnancy experience are the ideal candidates.

Less likely to help

People without systemic autoimmune or rheumatic conditions, men, or individuals whose health concerns are unrelated to pregnancy or reproductive care are unlikely to benefit directly from this work.

What this research studies

You would be asked about your experiences with fertility, pregnancy care, and access to treatments through interviews with researchers. Doctors who treat people with these conditions will also be interviewed about how policies shape their prescribing and referral choices. The team will analyze national insurance claims to compare pregnancy outcomes (like severe maternal complications) and medication use among women with these conditions. Together these methods aim to link patient experiences, clinician decisions, and policy factors to suggest ways to improve care.

Why it matters

Potential benefit: The findings could pinpoint policy changes that improve access to effective treatments and safer pregnancy care for people with systemic autoimmune and rheumatic diseases.

How similar studies have gone: Previous research has shown worse pregnancy outcomes for women with these conditions, but linking those outcomes to health policies and clinician decision-making is relatively new.

Where this research is happening

  • University of Pittsburgh at Pittsburgh
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Talabi, Mehret Birru — University of Pittsburgh at Pittsburgh
  • Study coordinator: Talabi, Mehret Birru

Related research

Other NIH-funded projects on the same topics.

  • Improving COVID-19 Vaccine Uptake Among Racial and Ethnic Minority Groups with Rheumatic Diseases

    A patient-facing program tests a multi-modal approach using storytelling videos and trained patient navigators to help Black and Latinx adults with autoimmune rheumatic diseases get recommended COVID-19 vaccines and boosters.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11371381

  • Long-term immune and health effects of COVID-19 in people with autoimmune rheumatic diseases

    This project looks at how COVID-19 changes immune responses and causes lingering symptoms in people with autoimmune rheumatic diseases like rheumatoid arthritis and lupus.

    NIH research Brigham and Women's Hospital · Boston, United States · NIH-11289321

  • How health policies impact women with autoimmune diseases during pregnancy

    This study is looking at how health policies affect women with autoimmune and rheumatic diseases during pregnancy, aiming to understand their experiences and access to care, so we can better support their health and treatment options.

    NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11167103

  • Training new scientists in rheumatic diseases

    This program is training new scientists to explore the causes and treatments of rheumatic diseases, like arthritis, by working together at the University of Pennsylvania and the Children’s Hospital of Philadelphia, so they can help improve care for patients of all ages.

    NIH research University of Pennsylvania · Philadelphia, United States · NIH-11094963

  • Helping Black and Latinx patients with rheumatic diseases get recommended COVID-19 vaccines

    This project helps Black and Latinx adults living with autoimmune rheumatic diseases get their recommended COVID-19 vaccines.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11061299

  • Effects of COVID-19 on patients with autoimmune diseases

    This study is looking at how COVID-19 affects people with autoimmune diseases like rheumatoid arthritis and lupus, to better understand their immune responses and how their treatments might change their reactions to the virus and vaccines, ultimately aiming to improve their health outcomes.

    NIH research Brigham and Women's Hospital · Boston, United States · NIH-11018582

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.