Condition

Prehabilitation clinical trials and research

• 26Clinical trials
• 6NIH research projects
• 16Countries

Newest Prehabilitation clinical trials

All recruiting trials (26)

• Preoperative functional optimization for adults undergoing major cardiac or abdominal surgery

  This study tests a four‑week prehabilitation program to improve fitness before elective major cardiac or abdominal surgery.

  Recruiting ASST Sette Laghi · Varese, VA and 1 other locations · NCT07851350

• Multimodal Prehabilitation for Gastric Cancer Patients

  This program tests whether a combined pre- and post-operative wellness plan can reduce inflammation after gastric cancer surgery in adults.

  Recruiting National University Hospital, Singapore · Singapore · NCT07839702

• Wireless home prehabilitation for older adults with NSCLC awaiting lung surgery

  This study tests whether a personalized home exercise program guided by wearable devices can improve lung function for older NSCLC patients preparing for curative lung surgery.

  Recruiting West China Hospital · Chengdu, Sichuan · NCT07809763

• Feasibility of high-dose multimodal prehabilitation for women awaiting gynecologic cancer surgery

  This study tests whether a high-dose, multimodal prehabilitation program can be delivered before gynecologic cancer surgery and whether patients prefer in-person, remote, or education-only approaches.

  Recruiting Queen's University · Kingston, Ontario · NCT07609082

• AI-assisted prehabilitation to help oral cancer patients return to work

  This trial will test an AI-assisted prehabilitation program to help adults with oral cancer reduce physical and emotional problems and return to work.

  Recruiting at 4 sites Taipei Veterans General Hospital, Taiwan · Taipei and 4 other locations · NCT07562100

• Prehab to get stronger before pancreatic cancer surgery

  This project will test whether adults with pancreatic cancer can follow a combined exercise, nutrition, and symptom-management program during chemotherapy to improve fitness and recovery before surgery.

  Recruiting University of Massachusetts, Worcester · Worester, Massachusetts · NCT07478185

• Multimodal prehabilitation before elective hip or knee replacement for frail older adults

  This program will test whether a tailored multimodal prehabilitation package can help frail adults aged 70 and older who are waiting at least two months for elective hip or knee replacement do better around the time of surgery.

  Recruiting University of Iceland · Reykjavik · NCT07465159

• Pre-surgery preparation program for older adults having lumbar fusion

  This trial will try a 6-week multimodal prehabilitation program to help people aged 75 and older having elective lumbar fusion recover independence and reduce complications after surgery.

  Recruiting at 4 sites Xuanwu Hospital, Beijing · Beijing, Beijing Municipality and 3 other locations · NCT07396077

• Pre-surgery conditioning and optimization for hip or knee replacement

  This will try a tailored pre-surgery program for adults with higher surgical risk (ASA ≥3) who are waiting at least eight weeks for elective hip or knee replacement to see if it improves recovery and reduces complications.

  Recruiting Medical University Innsbruck · Innsbruck, Tyrol · NCT07394582

• Prehab plus inspiratory muscle training before lung cancer surgery

  This trial will test whether adding inspiratory muscle training to a prehabilitation program helps people with resectable lung cancer have fewer breathing problems after surgery.

  Recruiting Swansea Bay University Health Board · Swansea · NCT07365072

• Virtual group prehabilitation education (GoPREPARE) for people awaiting cancer surgery

  This trial will test whether a virtual group prehabilitation class called GoPREPARE helps adults waiting for elective cancer surgery improve their fitness, nutrition, and readiness for surgery.

  Recruiting University Hospital Southampton NHS Foundation Trust · Plymouth, Devon · NCT07278622

• Seismocardiography to gauge fitness and predict outcomes before esophageal cancer surgery

  A noninvasive seismocardiography device is tested to see if it can quickly estimate a patient’s fitness and help predict surgical outcomes for adults with esophageal cancer who are planning curative treatment.

  Recruiting at 3 sites Guy's and St Thomas' NHS Foundation Trust · Guildford and 3 other locations · NCT07159711

• Multimodal prehabilitation combining exercise, nutrition, and psychological support to improve chemotherapy response in early breast cancer

  This trial will try a combined program of exercise, nutrition, and psychological support during neoadjuvant chemotherapy to see if it improves tumor response in women with early-stage (I–III) breast cancer.

  Recruiting Hospital Clinic of Barcelona · Barcelona · NCT07107594

• Home-based multimodal prehabilitation for people awaiting CABG

  This project will try a home-based program of exercise, nutrition, and psychological support to see if it is feasible and acceptable for adults waiting for elective coronary artery bypass graft surgery.

  Recruiting Copenhagen University Hospital, Rigshospitalet · Copenhagen · NCT07035171

• Telemedicine-guided prehabilitation to reduce urinary incontinence after prostatectomy

  In men planning radical prostatectomy for localized prostate cancer, this study tests a telemedicine-supported prehabilitation and rehabilitation program to see if it lowers postoperative urinary incontinence.

  Recruiting University Hospital Olomouc · Olomouc · NCT06981026

• Prepare for Your Surgery program for people with frailty

  This program gathers medical and frailty information and provides pre-surgery preparation for adults identified as frail who are scheduled for elective surgery at Hospital Clínico UC-Christus.

  Recruiting Pontificia Universidad Catolica de Chile · Santiago, Santiago Metropolitan and 1 other locations · NCT06857981

• Intensive lifestyle intervention for patients undergoing ventral hernia repair

  This study tests if a special program that helps people change unhealthy habits can reduce complications after surgery for ventral hernia repair.

  Recruiting Bispebjerg Hospital · Herlev and 2 other locations · NCT06611462

• Using auricular acupressure to improve health before lung surgery

  This study is testing whether auricular acupressure can help improve the health and well-being of people aged 50 and older who are getting ready for major lung surgery.

  Recruiting University of Chicago · Chicago, Illinois · NCT06516198

• Improving cognitive and physical health before lung surgery in older adults

  This study is testing if a special program of brain exercises and physical therapy before lung surgery can help older adults think better and recover faster afterward.

  Recruiting Military Medical Academy, Belgrade, Serbia · Belgrade · NCT06339268

• Prehabilitation with resistance training for women with breast cancer before surgery

  This study tests if a structured resistance training program can help postmenopausal women with breast cancer improve their muscle strength and quality of life before surgery compared to those who only receive standard care.

  Recruiting at 2 sites Universidad de La Frontera · Santiago and 1 other locations · NCT06309290

• Exercise program for patients with Multiple Myeloma before stem cell transplant

  This study tests whether a personalized exercise program can help people with Multiple Myeloma feel better before their stem cell transplant compared to regular exercise advice.

  Recruiting University of Alberta · Edmonton, Alberta · NCT06280924

• Improving health before colorectal cancer surgery for older patients with malnutrition

  This study is testing whether older patients with colorectal cancer who are malnourished can do better before surgery by focusing on nutrition alone or nutrition plus exercise.

  Recruiting McGill University · Montreal, Quebec · NCT05999370

• Effect of strength training before knee surgery on recovery and satisfaction

  This study tests if doing strength training before knee surgery can help patients recover better and feel more satisfied after their operation.

  Recruiting Molde University College · Molde, Møre og Romsdal · NCT05892133

• Improving preoperative care for pancreatic surgery patients

  This study is testing a new health program to see if it helps patients get stronger and recover faster after pancreatic surgery.

  Recruiting at 13 sites Maastricht University Medical Center · 's-Hertogenbosch and 12 other locations · NCT05851534

• Exercise program for women with ovarian cancer before surgery

  This study tests whether a structured exercise program can help women with advanced ovarian cancer get stronger and recover better before their surgery.

  Recruiting Nova Scotia Health Authority · Halifax, Nova Scotia · NCT05364879

• Improving fitness during chemotherapy for liver cancer patients

  This study is testing a 16-week program that combines exercise, nutrition, and support to see if it helps liver cancer patients feel fitter during chemotherapy and before surgery compared to those who only get support right before surgery.

  Recruiting Institut Investigacio Sanitaria Pere Virgili · Tarragona · NCT04520737

NIH-funded research (6)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Optimizing a prehabilitation program for kidney transplant candidates on dialysis

  A program to improve physical function and readiness for kidney transplant in people on dialysis is being developed and tested to help candidates stay healthier while they wait.

  NIH research New York University School of Medicine · New York, United States · NIH-11421433

• Nutrition and exercise before surgery to reduce cancer inflammation in AI/AN patients

  A prehabilitation program combining nutrition and exercise is tested to lower inflammatory markers in American Indian/Alaska Native cancer patients before surgery.

  NIH research University of Arizona · Tucson, United States · NIH-11382109

• Improving brain health to prevent Alzheimer's disease after kidney transplants

  This study is looking at how brain exercises can help older people who have had a kidney transplant stay sharp and lower their chances of getting Alzheimer's or other memory problems.

  NIH research New York University School of Medicine · New York, United States · NIH-10978225

• Improving prehabilitation for older adults before lung cancer surgery

  This study is all about making it easier for older adults with lung cancer to prepare for surgery by using a friendly app called BeFitMe™ that helps them stay active, eat well, and get support from others, while also listening to their feedback to improve the program.

  NIH research University of Chicago · Chicago, United States · NIH-10912030

• Exercise training for patients with multiple myeloma before stem cell transplantation

  This study is looking at how an 8-week home exercise program can help people with multiple myeloma feel stronger and healthier while getting ready for a stem cell transplant, with virtual support to guide them along the way.

  NIH research Boston University (Charles River Campus) · Boston, United States · NIH-10898403

• Improving health before cancer surgery in American Indian patients through nutrition and exercise

  This study is looking to help American Indian and Alaska Native cancer patients feel better before their surgery by offering a program that includes healthy eating and exercise, aiming to reduce inflammation and improve their overall health for better surgery outcomes.

  NIH research University of Arizona · Tucson, United States · NIH-10873797

Related topics

Quick answers

How many Prehabilitation clinical trials are recruiting right now?

26, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in Canada (4 trials), United Kingdom (3 trials), United States (2 trials), Spain (2 trials), China (2 trials). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →