Home-based multimodal prehabilitation for people awaiting CABG
Official title: CABGpreHAB- Home-based Multimodal Prehabilitation (CABGpreHAB) for Elective Patients Awaiting CABG-surgery - a Feasibility Study Protocol
Run by Copenhagen University Hospital, Rigshospitalet · NCT07035171 · Data updated 2026-11-12
This project will try a home-based program of exercise, nutrition, and psychological support to see if it is feasible and acceptable for adults waiting for elective coronary artery bypass graft surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Copenhagen University Hospital, Rigshospitalet Academic / other |
| Locations | 1 site (Copenhagen) |
| Status | Recruiting |
| Started | June 24, 2025 |
| Main results expected | June 18, 2026 |
| Study ends | July 18, 2026 |
| Registry record updated | June 29, 2025 |
| Trial ID | NCT07035171 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Danish-speaking adults (≥18 years) scheduled for elective isolated first-time CABG with at least two weeks before surgery who can safely perform exercise and provide informed consent.
✕Probably not a fit
Patients with recent unstable angina or MI, significant left main stenosis, LVEF <35%, severe heart failure (NYHA IV), major arrhythmias, cognitive or orthopedic limitations, or inability to consent are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
CABGpreHAB is a randomized pilot at Rigshospitalet that compares a home-based multimodal prehabilitation program plus usual care versus usual care alone for adults scheduled for elective first-time CABG. The intervention combines tailored exercise, nutritional advice, and psychological support delivered in the weeks before surgery, with remote and in-person monitoring of adherence and fidelity. Primary outcomes are feasibility measures such as recruitment, retention, attrition, fidelity, and adherence, while clinical and functional measures are collected to inform a larger trial. Eligible participants are adults who speak Danish, are at least two weeks from surgery, and have no unstable cardiac conditions or contraindications to exercise.
Why it matters
Potential benefit: If successful, the program could increase patients' functional capacity before surgery, reduce postoperative complications, and speed return to independence.
How similar studies have gone: Multimodal prehabilitation has shown benefits in some elective non-cardiac surgeries, but randomized data specifically for CABG are limited, so this approach is relatively novel in cardiac surgery.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Planned to have elective isolated first-time CABG surgery. * 18 years or older * Two weeks or more before surgery * Speaks and understands Danish. * Gives written informed consent. Exclusion Criteria: * Patient with unstable angina pectoris and/ or MI during the last two weeks. * Left main stem stenosis \>50% * Left ventricular ejection fraction \< 35% * Significant ventricular arrhythmia * Orthopedic or neurologic preconditions precluding exercise training. * Inability to attend the prehabilitation program due to physical limitations. * Patients who have cognitive deficits that would disqualify prehabilitation. * Severe heart failure, NYHA Class IV * Lack of capacity to consent
Where it's running
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The Department of Heart and Lung Surgery, Copenhagen University hospital Rigshospitalet
Copenhagen, Denmark Recruiting
Study contacts
- Principal investigator: Ida E Hoejskov, PhD — Department of Heart Disease, Rigshospitalet, Copenhagen University Hospital
- Study coordinator: Dorte Baek Olsen, PhD student
- Email: dorte.baek.olsen@regionh.dk
- Phone: +4526625705
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.