Exercise program for patients with Multiple Myeloma before stem cell transplant
Official title: Multiple Myeloma Exercise Prehabilitation for Individuals Awaiting a Stem Cell Transplantation (MOTIVATE): A Randomized Controlled Feasibility Trial
Run by University of Alberta · NCT06280924 · Data updated 2026-11-12
This study tests whether a personalized exercise program can help people with Multiple Myeloma feel better before their stem cell transplant compared to regular exercise advice.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | University of Alberta Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Edmonton, Alberta) |
| Status | Recruiting |
| Started | August 6, 2024 |
| Main results expected | March 31, 2027 |
| Study ends | March 31, 2027 |
| Registry record updated | October 23, 2026 |
| Trial ID | NCT06280924 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older with a diagnosis of Multiple Myeloma who are eligible for a stem cell transplant and currently undergoing chemotherapy.
✕Probably not a fit
Patients whose disease status or comorbidities prevent them from participating in exercise or those unable to commit to the program may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the feasibility and effectiveness of a tailored exercise program for individuals with Multiple Myeloma undergoing chemotherapy prior to a stem cell transplant. Participants will be recruited to engage in a 10-week exercise intervention, comparing outcomes with those receiving standard physical activity counseling. The study will also assess the acceptability of a mobile app designed to support healthy living during treatment. The approach includes both in-person and virtual formats to accommodate different needs.
Why it matters
Potential benefit: If successful, this program could help improve physical fitness, muscle mass, strength, and quality of life for patients undergoing chemotherapy.
How similar studies have gone: While similar approaches have been explored, this specific intervention's feasibility and effectiveness in this patient population is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Have a diagnosis of Multiple Myeloma 2. Be transplant eligible 3. Be undergoing chemotherapy prior to, or following an autologous stem cell transplant as part of their cancer treatment; or transplant ineligible. 4. Be an Alberta resident 5. Be ≥18 years of age 6. Be able to read and understand English. Exclusion Criteria: 1. Their disease status/comorbidities preclude exercise testing or participation 2. They are unable to commit to the 10-week exercise program and/or testing sessions at the Cancer Rehabilitation Clinic at the University of Alberta 3. They do not have regular access to the internet and/or an electronic device in the home.
Where it's running
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University of Alberta/ Cross Cancer Institute
Edmonton, Alberta, Canada Recruiting
Study contacts
- Study coordinator: Margaret L McNeely, PhD
- Email: mmcneely@ualberta.ca
- Phone: 7802890972
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.