Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Exercise program for patients with Multiple Myeloma before stem cell transplant

Official title: Multiple Myeloma Exercise Prehabilitation for Individuals Awaiting a Stem Cell Transplantation (MOTIVATE): A Randomized Controlled Feasibility Trial

Run by University of Alberta · NCT06280924 · Data updated 2026-11-12

This study tests whether a personalized exercise program can help people with Multiple Myeloma feel better before their stem cell transplant compared to regular exercise advice.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorUniversity of Alberta
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Edmonton, Alberta)
StatusRecruiting
StartedAugust 6, 2024
Main results expectedMarch 31, 2027
Study endsMarch 31, 2027
Registry record updatedOctober 23, 2026
Trial IDNCT06280924 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with a diagnosis of Multiple Myeloma who are eligible for a stem cell transplant and currently undergoing chemotherapy.

Probably not a fit

Patients whose disease status or comorbidities prevent them from participating in exercise or those unable to commit to the program may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the feasibility and effectiveness of a tailored exercise program for individuals with Multiple Myeloma undergoing chemotherapy prior to a stem cell transplant. Participants will be recruited to engage in a 10-week exercise intervention, comparing outcomes with those receiving standard physical activity counseling. The study will also assess the acceptability of a mobile app designed to support healthy living during treatment. The approach includes both in-person and virtual formats to accommodate different needs.

Why it matters

Potential benefit: If successful, this program could help improve physical fitness, muscle mass, strength, and quality of life for patients undergoing chemotherapy.

How similar studies have gone: While similar approaches have been explored, this specific intervention's feasibility and effectiveness in this patient population is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Have a diagnosis of Multiple Myeloma
2. Be transplant eligible
3. Be undergoing chemotherapy prior to, or following an autologous stem cell transplant as part of their cancer treatment; or transplant ineligible.
4. Be an Alberta resident
5. Be ≥18 years of age
6. Be able to read and understand English.

Exclusion Criteria:

1. Their disease status/comorbidities preclude exercise testing or participation
2. They are unable to commit to the 10-week exercise program and/or testing sessions at the Cancer Rehabilitation Clinic at the University of Alberta
3. They do not have regular access to the internet and/or an electronic device in the home.

Where it's running

  • University of Alberta/ Cross Cancer Institute
    Edmonton, Alberta, Canada
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.