Improving cognitive and physical health before lung surgery in older adults
Official title: Effects of Preoperative Cognitive and Physical Optimization in the Prevention of Postoperative Cognitive Deficit in Elderly Patients With Lung Resection
Run by Military Medical Academy, Belgrade, Serbia · NCT06339268 · Data updated 2026-11-12
This study is testing if a special program of brain exercises and physical therapy before lung surgery can help older adults think better and recover faster afterward.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 60 Years and up |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | Military Medical Academy, Belgrade, Serbia Academic / other |
| Locations | 1 site (Belgrade) |
| Status | Recruiting |
| Started | November 1, 2023 |
| Main results expected | November 1, 2025 |
| Study ends | March 1, 2026 |
| Registry record updated | April 24, 2025 |
| Trial ID | NCT06339268 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are elderly individuals over 60 years old who are scheduled for elective lung resection and can use a phone or tablet.
✕Probably not a fit
Patients under 60 years of age or those with significant psychiatric or neurological comorbidities may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to prevent postoperative cognitive deficits in elderly patients undergoing lung resection by implementing a prehabilitation program. Participants will be randomly assigned to either an intervention group, which will receive cognitive stimulation and physical therapy for one month prior to surgery, or a control group that will receive standard treatment. The cognitive training will utilize the Cognifit app, and physical therapy will include exercises tailored to improve mobility and strength. The effectiveness of this approach will be assessed through pre- and postoperative cognitive evaluations.
Why it matters
Potential benefit: If successful, this study could significantly reduce the incidence of cognitive deficits following lung surgery in older patients.
How similar studies have gone: While there is existing literature on cognitive deficits post-surgery, this specific prehabilitation approach is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Older than 60 years * Elective lung resection operations * Patients who can use a phone or tablet * Patients who agreed to participate in the study * Clinical scale of weakness less than 6 * The American Society of Anesthesiologists (ASA) status I, II, III, IV Exclusion Criteria: * Under 60 years of age * Significant psychiatric comorbidity (schizophrenia, depression, alcoholism) * Significant neurological comorbidity (dementia, cerebrovascular insult in the last 6 months, parkinsonism) * Patient's refusal to participate in the study * The inability of the patient to use a tablet or phone * The American Society of Anesthesiologists (ASA) status V and VI * Clinical weakness scale 6 and above
Where it's running
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Military Medical Academy
Belgrade, Serbia Recruiting
Study contacts
- Principal investigator: Vojislava Neskovic, PhD — Military Medical Academy, Bulgaria
- Study coordinator: Vojislava Neskovic, PhD
- Email: vojkan43@gmail.com
- Phone: +381641775320
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.