Feasibility of high-dose multimodal prehabilitation for women awaiting gynecologic cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

ADAPT is a single-center pilot trial comparing three prehabilitation delivery models—in-person, remote with coaching and a web app, and education-only—for women preparing for ovarian cancer surgery. The study aims to see if participants can reach at least 10 MET-hours per week of aerobic exercise before surgery and which delivery method patients prefer. It evaluates feasibility, acceptability, and practicality to inform future larger trials, with attention to barriers such as travel and scheduling. The trial also considers how multimodal prehabilitation may influence postoperative recovery by targeting fitness, nutrition, and psychological support. Participants may choose their group or be randomly assigned, and the study is designed to identify the most workable approach for gynecologic cancer patients undergoing cytoreductive surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female
* Aged ≥18 years
* Scheduled for cytoreductive surgery for a gynecologic mass suspected or confirmed of cancer
* Surgery planned ≥3 weeks from time of booking
* No contraindications to exercise on the CSEP Get Active Questionnaire
* Able to provide written informed consent
* Able to understand and communicate in English

Exclusion Criteria:

* Pregnancy
* Cervical pathologies
* Surgery scheduled \<3 weeks from booking
* Receiving neoadjuvant chemotherapy
* Positive contraindications to exercise on the CSEP Get Active Questionnaire
* End-stage or advanced renal disease limiting safe protein supplementation
* Malnutrition as assessed by a registered dietician

Where it's running

• Kingston Health Sciences Centre
  Kingston, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Jordan Leitch, MSc, MD, FRCPC — Queen's University
• Study coordinator: Deborah DuMerton
• Email: deborah.dumerton@kingstonhsc.ca
• Phone: 613-484-7322

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.