Nutrition and exercise before surgery to reduce cancer inflammation in AI/AN patients
Official title: A Nutrition and Exercise Prehabilitation Intervention on Inflammatory Biomarkers in American Indian Cancer Patients
Funded at University of Arizona · NIH-11382109 · Data updated 2026-11-12
A prehabilitation program combining nutrition and exercise is tested to lower inflammatory markers in American Indian/Alaska Native cancer patients before surgery.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $271,631 |
| NIH project number | 5K08CA276137-04 |
| Project ID | NIH-11382109 on NIH RePORTER |
Who could benefit from this research
✓Could help
AI/AN adults with cancer who are candidates for surgery and have obesity-related inflammation.
✕Less likely to help
Patients without obesity-related inflammation or those not undergoing planned cancer surgery may see limited or no benefit.
What this research studies
This project aims to help AI/AN cancer patients by starting a structured nutrition and exercise plan before surgery to reduce harmful inflammation linked to obesity and cancer. The team will measure inflammatory biomarkers in blood and look at how the intervention might affect patients’ daily living and recovery. The study adapts prehabilitation concepts to a population that has historically been underrepresented in research. Participation would involve guidance from clinicians and exercise/nutrition specialists prior to surgery, with monitoring over time. The goal is to improve surgical outcomes and long-term health for AI/AN communities.
Why it matters
Potential benefit: If successful, patients may experience lower inflammation and better recovery after cancer surgery.
How similar studies have gone: Some prehabilitation studies in other populations show favorable inflammation and recovery signals, but AI/AN-focused work is novel.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Erdrich, Jennifer a — University of Arizona
- Study coordinator: Erdrich, Jennifer a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.