NIH-funded research Career grant

Nutrition and exercise before surgery to reduce cancer inflammation in AI/AN patients

Official title: A Nutrition and Exercise Prehabilitation Intervention on Inflammatory Biomarkers in American Indian Cancer Patients

Funded at University of Arizona · NIH-11382109 · Data updated 2026-11-12

A prehabilitation program combining nutrition and exercise is tested to lower inflammatory markers in American Indian/Alaska Native cancer patients before surgery.

More Prehabilitation research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Arizona
NIH-funded
Lab location1 site (Tucson, United States)
Project startJuly 1, 2023
Project endJune 30, 2028
Funding year2026
Award (this year)$271,631
NIH project number5K08CA276137-04
Project IDNIH-11382109 on NIH RePORTER

Who could benefit from this research

Could help

AI/AN adults with cancer who are candidates for surgery and have obesity-related inflammation.

Less likely to help

Patients without obesity-related inflammation or those not undergoing planned cancer surgery may see limited or no benefit.

What this research studies

This project aims to help AI/AN cancer patients by starting a structured nutrition and exercise plan before surgery to reduce harmful inflammation linked to obesity and cancer. The team will measure inflammatory biomarkers in blood and look at how the intervention might affect patients’ daily living and recovery. The study adapts prehabilitation concepts to a population that has historically been underrepresented in research. Participation would involve guidance from clinicians and exercise/nutrition specialists prior to surgery, with monitoring over time. The goal is to improve surgical outcomes and long-term health for AI/AN communities.

Why it matters

Potential benefit: If successful, patients may experience lower inflammation and better recovery after cancer surgery.

How similar studies have gone: Some prehabilitation studies in other populations show favorable inflammation and recovery signals, but AI/AN-focused work is novel.

Where this research is happening

  • University of Arizona
    Tucson, United States
    Active

Researchers

  • Principal investigator: Erdrich, Jennifer a — University of Arizona
  • Study coordinator: Erdrich, Jennifer a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.