Clinical trial Recruiting at 4 sites Interventional Ages 20 to 70

AI-assisted prehabilitation to help oral cancer patients return to work

Official title: Develop and Evaluate An Artificial Intelligence Assisted Prehabilitation Program for Returning to Work and Cost-effectiveness Analysis in Patients With Oral Cancer

Run by Taipei Veterans General Hospital, Taiwan · NCT07562100 · Data updated 2026-11-12

This trial will test an AI-assisted prehabilitation program to help adults with oral cancer reduce physical and emotional problems and return to work.

More Oral Cancer trials

Quick facts

Study typeInterventional
Ages20 Years to 70 Years
SexAll
Enrollment650 (estimated)
SponsorTaipei Veterans General Hospital, Taiwan
Government
Locations5 sites (Taipei and 4 other locations)
StatusRecruiting
StartedSeptember 27, 2024
Main results expectedJuly 31, 2028
Study endsDecember 1, 2029
Registry record updatedMay 1, 2026
Trial IDNCT07562100 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 20–69 newly diagnosed with oral cancer who are scheduled for cancer-related treatment, can use a mobile phone, and can give informed consent are ideal candidates.

Probably not a fit

Patients at high risk for exercise-related harms, those with cognitive impairment or psychiatric disorders, or those unable to use a smartphone are unlikely to benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial develops and tests an Artificial Intelligence Assisted Prehabilitation Program (AI APP) tailored for adults newly diagnosed with oral cancer, integrating an AI-based physiotherapy app with conventional physiotherapy and scar management. The first phase identifies return-to-work needs from diagnosis through survivorship to inform the AI features, and participants are then compared with and without the AI APP to measure effects. Key outcomes include physical and psychological distress, fear of recurrence, coping self-efficacy, communication and motor function, quality of life, return-to-work rates, and a comprehensive cost-effectiveness analysis. Family caregivers and healthcare professionals are involved for training and feedback, and participation requires smartphone use and access to the participating Taipei hospitals.

Why it matters

Potential benefit: If successful, the program could help patients recover function, reduce distress, and return to work sooner while potentially lowering care costs.

How similar studies have gone: Digital prehabilitation and AI-based rehabilitation tools have shown promise in other cancer and rehab settings, but AI-assisted return-to-work programs specifically for oral cancer remain largely untested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult (\> 20 years old and younger than 70 years old)
* Newly diagnosed as OC and scheduled to receive cancer-related treatment
* Able to use Mobile phone
* Willing to sign an informed consent form after receiving a detailed explanation of the study's aims and procedures
* Healthcare professionals involved in patients' care, including doctors, nurses, case managers, dietitians, rehabilitation therapists, and psychologists
* Family members who are primary caregivers of the participating patients, engaged in different stages of medical care

Exclusion Criteria:

* Risk populations for walking or performing exercise
* Patients with cognitive impairment or psychiatric diseases

Where it's running

  • National Taiwan University Hospital
    Taipei, Taiwan
    Recruiting
  • National Yang Ming Chiao Tung University
    Taipei, Taiwan
    Recruiting
  • National Yang Ming Chiao Tung University
    Taipei, Taiwan
    Recruiting
  • Taipei Veterans General Hospital
    Taipei, Taiwan
    Recruiting
  • National Yang Ming Chiao Tung University
    Taipei, Taiwan
    Enrolling by invitation

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.