AI-assisted prehabilitation to help oral cancer patients return to work

Develop and Evaluate An Artificial Intelligence Assisted Prehabilitation Program for Returning to Work and Cost-effectiveness Analysis in Patients With Oral Cancer

Not applicable Interventional Taipei Veterans General Hospital, Taiwan · NCT07562100

This trial will test an AI-assisted prehabilitation program to help adults with oral cancer reduce physical and emotional problems and return to work.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment650 (estimated)
Ages20 Years to 70 Years
SexAll
SponsorTaipei Veterans General Hospital, Taiwan Government
Locations5 sites (Taipei and 4 other locations)
Trial IDNCT07562100 on ClinicalTrials.gov

What this trial studies

The trial develops and tests an Artificial Intelligence Assisted Prehabilitation Program (AI APP) tailored for adults newly diagnosed with oral cancer, integrating an AI-based physiotherapy app with conventional physiotherapy and scar management. The first phase identifies return-to-work needs from diagnosis through survivorship to inform the AI features, and participants are then compared with and without the AI APP to measure effects. Key outcomes include physical and psychological distress, fear of recurrence, coping self-efficacy, communication and motor function, quality of life, return-to-work rates, and a comprehensive cost-effectiveness analysis. Family caregivers and healthcare professionals are involved for training and feedback, and participation requires smartphone use and access to the participating Taipei hospitals.

Who should consider this trial

Good fit: Adults aged 20–69 newly diagnosed with oral cancer who are scheduled for cancer-related treatment, can use a mobile phone, and can give informed consent are ideal candidates.

Not a fit: Patients at high risk for exercise-related harms, those with cognitive impairment or psychiatric disorders, or those unable to use a smartphone are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, the program could help patients recover function, reduce distress, and return to work sooner while potentially lowering care costs.

How similar studies have performed: Digital prehabilitation and AI-based rehabilitation tools have shown promise in other cancer and rehab settings, but AI-assisted return-to-work programs specifically for oral cancer remain largely untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult (\> 20 years old and younger than 70 years old)
* Newly diagnosed as OC and scheduled to receive cancer-related treatment
* Able to use Mobile phone
* Willing to sign an informed consent form after receiving a detailed explanation of the study's aims and procedures
* Healthcare professionals involved in patients' care, including doctors, nurses, case managers, dietitians, rehabilitation therapists, and psychologists
* Family members who are primary caregivers of the participating patients, engaged in different stages of medical care

Exclusion Criteria:

* Risk populations for walking or performing exercise
* Patients with cognitive impairment or psychiatric diseases

Where this trial is running

Taipei and 4 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Oral CancerPsychological DistressCommunication Aids for DisabledPhysiotherapyReturn to WorkPrehabilitationPhysical Symptom DistressMotor Function
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.