Condition

Inflammatory Bowel Disease (IBD) clinical trials and research

• 39Clinical trials
• 2NIH research projects
• 24Countries

Newest Inflammatory Bowel Disease (IBD) clinical trials

All recruiting trials (39)

• Moderate breathing and movement: Can regular exercise help people with quiescent inflammatory bowel disease feel better?

  This trial tests whether a moderate-intensity exercise program improves quality of life for adults with Crohn's disease or ulcerative colitis who are currently in clinical remission.

  Recruiting Mahidol University · Bangkok Noi, Bangkok · NCT07775794

• Mediterranean Diet and Time-Restricted Feeding in Ulcerative Colitis in Remission

  This study tests whether a Mediterranean diet, with or without an 8-hour eating window, helps gut health and quality of life in adults with ulcerative colitis in remission.

  Recruiting Pontificia Universidad Catolica de Chile · Santiago, Santiago Metropolitan · NCT07752446

• Screening for lipid disorders in children and teens with chronic diseases to flag cardiovascular risk

  This study tests a blood test and a questionnaire to screen children and teens with chronic conditions for lipid metabolism disorders and familial hyperlipidemia.

  Recruiting Jena University Hospital · Jena · NCT07716488

• Wearable data to spot IBD flareups in people with ulcerative colitis or Crohn's disease

  This study tests whether heart‑rate variability from participants’ own wearables can help predict IBD flares.

  Recruiting at 2 sites Maastricht University Medical Center · 's-Hertogenbosch and 2 other locations · NCT07647640

• PVT401 in healthy adults

  This trial will test intravenous PVT401 in healthy adults who carry the HLA DRB4*0101 or DRB4*0103 allele to see how the drug behaves in the body and whether single and multiple doses are safe.

  Recruiting Phase 1 Parvus Therapeutics, Inc. · Melbourne, Victoria · NCT07423000

• Dexamethasone before infliximab for moderate-to-severe Crohn's disease and ulcerative colitis

  This project will test whether giving an IV dose of dexamethasone before infliximab infusions prevents allergic reactions in people aged 14–80 with moderate-to-severe Crohn's disease or ulcerative colitis.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT07385131

• DISC-0974-201 for adults with IBD-related anemia

  This Phase 2 trial will test whether DISC-0974-201 helps adults with inflammatory bowel disease who have anemia driven by inflammation.

  Recruiting at 15 sites Phase 2 Disc Medicine, Inc · Birmingham, Alabama and 14 other locations · NCT07368972

• DISC-0974-201 for adults with IBD-related anemia

  This Phase 2 trial will test whether DISC-0974-201 helps adults with inflammatory bowel disease who have anemia driven by inflammation.

  Recruiting at 15 sites Phase 2 Disc Medicine, Inc · Birmingham, Alabama and 14 other locations · NCT07368972

• Switching to guselkumab for adults with active IBD after ustekinumab

  We will try guselkumab (Tremfya) in adults with active IBD whose symptoms didn't improve enough on ustekinumab.

  Recruiting at 12 sites TIDHI Innovation Inc. · Calgary, Alberta and 13 other locations · NCT07245394

• Colorectal Cancer Screening: a Blood Test for a Better Path to Colonoscopy

  A blood-based biomarker test using five ofCS markers is being tested to better sort people who need a colonoscopy from those who don’t.

  Recruiting at 2 sites Nordsjaellands Hospital · Hillerød and 1 other locations · NCT07237984

• Zymfentra (infliximab-dyyb) real-world cohort

  This project will see if Zymfentra (infliximab-dyyb) reduces symptoms over one year in adults with Crohn's disease, ulcerative colitis, or indeterminate colitis who are starting or switching to the drug as part of routine care.

  Recruiting at 11 sites University of North Carolina, Chapel Hill · New Haven, Connecticut and 10 other locations · NCT07237516

• Reducing ultra-processed foods in children and teens with IBD

  This project will test whether short nutrition handouts or handouts plus a brief video can help children and teens with IBD eat fewer ultra-processed foods.

  Recruiting Connecticut Children's Medical Center · Hartford, Connecticut · NCT07224113

• SMART-IBD app for teens with inflammatory bowel disease

  This will test whether the SMART-IBD smartphone app helps adolescents ages 13–17 with IBD take their medicines and manage symptoms better than completing daily diaries alone.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07195123

• Remote adapted physical activity program to improve life for adults with IBD

  This pilot will test whether a home-delivered adapted physical activity program can improve quality of life for adults with Crohn's disease or ulcerative colitis.

  Recruiting Raincy Montfermeil Hospital Group · Montfermeil and 1 other locations · NCT07191106

• Argentina registry for people with Crohn's disease and ulcerative colitis.

  Collects routine care information from people of all ages in Argentina who have Crohn's disease or ulcerative colitis to track treatments, complications, and outcomes.

  Recruiting Grupo Argentino de Enfermedad de Crohn y Colitis Ulcerosa · Córdoba, Córdoba Province · NCT07155148

• Microplastic levels in children with and without inflammatory bowel disease

  This project will test whether children with Crohn's disease or ulcerative colitis have higher levels of microplastics in intestinal tissue, stool, urine, or blood than children without IBD.

  Recruiting Medical University of Gdansk · Gdansk · NCT07141238

• Phase 2 testing of new therapies for moderate-to-severe inflammatory bowel disease

  The study will try two experimental medicines, MT-501 and MT-201, to see if they are safe and help adults with moderately to severely active Crohn's disease or ulcerative colitis.

  Recruiting at 66 sites Phase 2 Mirador Therapeutics, Inc. · Birmingham, Alabama and 65 other locations · NCT07113522

• Cardiovascular health in children and young adults with chronic conditions

  This project will see if children and young adults (ages 6-25) with chronic health conditions show early signs of aging in large and small blood vessels using noninvasive imaging and clinical tests.

  Recruiting Semmelweis University · Budapest and 2 other locations · NCT07086989

• TIDHI Healing Circuits mental health program for people with IBD

  This study tests whether Healing Circuits™ delivered by a social worker or via a self-guided online program helps adults with IBD who have moderate anxiety or depression.

  Recruiting TIDHI Innovation Inc. · North York, Ontario · NCT07013578

• Finding who is at high risk for inflammatory bowel disease

  This project will see if clinical features, blood markers, genetics, and the gut microbiome can predict who will develop IBD among people at higher risk.

  Recruiting Seoul National University Hospital · Seoul · NCT07011979

• Telehealth monitoring for patients with inflammatory bowel disease

  This study tests if a nurse-led telehealth program can help people with inflammatory bowel disease stick to their medications and improve their quality of life compared to regular care.

  Recruiting Istanbul University - Cerrahpasa · Istanbul · NCT06971627

• 18F-FAPI PET to detect intestinal lesions and measure IBD activity

  This project will test whether 18F-FAPI PET scans can detect intestinal lesions and measure disease activity in adults with inflammatory bowel disease.

  Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Chongqing, Chongqing Municipality · NCT06945549

• Observing IBD patients with fatty liver disease

  This study looks at people with inflammatory bowel disease to see how common fatty liver disease is among them and how it affects their overall health.

  Recruiting Shanghai East Hospital · Shanghai · NCT06939569

• High-end versus mid-end intestinal ultrasound for finding ileocolonic inflammation in IBD

  This study tests whether a high-end intestinal ultrasound machine finds inflammation in the ileum and colon of adults with IBD more accurately than a mid-end ultrasound, using colonoscopy as the comparison.

  Recruiting Asian Institute of Gastroenterology, India · Hyderabad, Telangana · NCT06938295

• Registry for pregnant individuals with Inflammatory Bowel Disease

  This study is collecting information from pregnant people with Inflammatory Bowel Disease to see how safe their treatments are for them and their babies.

  Recruiting CorEvitas · Wilmington, North Carolina · NCT06910553

• Assessing how Hepatitis B affects Inflammatory Bowel Disease

  This study is trying to see how having hepatitis B affects the symptoms and treatment outcomes for people with inflammatory bowel disease in Egypt.

  Recruiting Tanta University · Tanta, Gharbyea · NCT06881238

• Elemental 028 Extra case series

  This project will try an upgraded Elemental 028 Extra amino-acid feed in adults and children with severe gut problems who need an elemental diet to see if they tolerate it and can stick with it.

  Recruiting Nutricia UK Ltd · Trowbridge · NCT06877923

• 12-week personalized aerobic program for adults with inactive or mildly active IBD

  This study will test whether a 12-week individualized aerobic exercise program helps adults (18–65) with inactive or mildly active Crohn's disease or ulcerative colitis improve fitness, control disease activity, and feel better overall.

  Recruiting Ningbo Medical Center Lihuili Hospital · Ningbo, Zhejiang · NCT06804733

• Comparing tests for diagnosing cytomegalovirus in patients with inflammatory bowel disease

  This study is testing different ways to diagnose cytomegalovirus in adults with inflammatory bowel disease who are having worse symptoms and need to be hospitalized.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, Bologna · NCT06793124

• Optimizing Infliximab Treatment for Inflammatory Bowel Disease

  This study is testing a new way to give infliximab to adults with moderate-to-severe inflammatory bowel disease who haven't improved with steroids, to see if personalized dosing can help them feel better.

  Recruiting Pontificia Universidad Catolica de Chile · Santiago · NCT06758024

• Comparing subcutaneous and intravenous vedolizumab for inflammatory bowel disease with remote monitoring

  This study is testing if a digital health system can help people with inflammatory bowel disease stick to their vedolizumab treatment, whether they receive it through an injection under the skin or through an IV, and how it affects their health over 22 weeks.

  Recruiting at 2 sites Mercy Medical Center · New Orleans, Louisiana and 5 other locations · NCT06750731

• Fermented plant-based diet for gut health and colitis

  This project will test whether a fermented, plant-based (vegan) diet improves gut barrier function and symptoms in people with ulcerative colitis or Crohn's disease and in healthy volunteers.

  Recruiting at 2 sites Region Skane · Malmö and 1 other locations · NCT06696222

• MYIBDDiet app to help adults with IBD manage their diet

  This project will test if the MYIBDDiet app helps adults with inflammatory bowel disease learn about and follow healthier eating over one month.

  Recruiting University of Alberta · Edmonton, Alberta · NCT06683105

• Tracking family members at risk for inflammatory bowel disease

  This study is trying to see if tracking family members of people with inflammatory bowel disease can help find out who is at risk of developing it and how to prevent it.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT06655415

• Patient registry for children and adolescents with inflammatory bowel disease

  This study collects health information from children and teens with inflammatory bowel disease to help improve treatment and care.

  Recruiting University of Giessen · Giessen · NCT06606756

• Cohort study of patients with and without Crohn's disease

  This study is trying to find new markers in the blood that can help us understand Crohn's disease better by comparing patients with Crohn's to those without any bowel issues.

  Recruiting Artialis · Liège · NCT06502873

• Analyzing gut microbiome data in inflammatory bowel disease

  This study is trying to understand how gut bacteria and genetics affect treatment responses in people with inflammatory bowel disease to help improve personalized care.

  Recruiting Kyunghee University Medical Center · Seoul · NCT06124833

• Observing the effects of vedolizumab in adults with ulcerative colitis or Crohn's disease in South Korea

  This study is looking at how well the medication vedolizumab works for adults in South Korea with moderate to severe ulcerative colitis or Crohn's disease who haven't had success with other treatments.

  Recruiting Takeda · Goyang-si, Gyeonggi-do · NCT05428345

• A platform for collecting health data on ME/CFS and Long Covid

  This study is trying to collect health information from adults with ME/CFS and Long Covid to help researchers better understand these conditions and improve future treatments.

  Recruiting Brain Inflammation Collaborative · Delafield, Wisconsin · NCT04806620

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Heart-rate biofeedback and coping skills to help teens with IBD feel less stressed

  This program teaches teens and young adults with Crohn's disease or ulcerative colitis breathing and heart‑rate biofeedback skills to lower stress, improve mood, and support gut health.

  NIH research Emory University · Atlanta, United States · NIH-11324588

• Improving mental health and disease management in youth with inflammatory bowel disease through biofeedback.

  This study is looking at how a special program that teaches teens with inflammatory bowel disease (IBD) to manage their stress and symptoms can help them feel better both mentally and physically.

  NIH research Emory University · Atlanta, United States · NIH-11124700

Related topics

Quick answers

How many Inflammatory Bowel Disease (IBD) clinical trials are recruiting right now?

39, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 24 countries. The most sites are in United States (10 trials), China (4 trials), Canada (4 trials), South Korea (3 trials), Chile (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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