Mediterranean Diet and Time-Restricted Feeding in Ulcerative Colitis in Remission

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this pilot randomized trial, 45 adults with ulcerative colitis in remission will be assigned to one of three groups for 12 weeks: Mediterranean diet, Mediterranean diet plus time-restricted feeding with an 8-hour eating window, or standard dietary advice. The main outcome is changes in stool short-chain fatty acids, with additional measures of inflammation, gastrointestinal symptoms, and quality of life. The study aims to see if these dietary strategies can improve gut health and patient well-being. Participants will follow diet plans and be monitored for adherence and safety. Results could inform dietary recommendations for UC management beyond pharmacologic therapy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 to 60 years
* Diagnosis of ulcerative colitis
* Clinical remission for at least 6 months
* Fecal calprotectin \< 250 µg/g in the last 3 months
* Daily eating window ≥ 11 hours

Exclusion Criteria:

* Active ulcerative colitis
* History of gastrointestinal surgery
* Liver or kidney disease
* Pregnancy
* Eating disorders
* Use of supplements (protein, antioxidants, probiotics)
* Current restrictive diets (vegetarian, vegan, gluten-free, low-FODMAP)
* High levels of physical activity

Where it's running

• Pontificia Universidad Católica de Chile
  Santiago, Santiago Metropolitan, Chile Recruiting

Study contacts

• Study coordinator: Alejandra Parada Daza, Phd
• Email: acparada@uc.cl
• Phone: +56994751585

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.