Clinical trial Recruiting at 1 site Observational Ages 2 and up

A platform for collecting health data on ME/CFS and Long Covid

Official title: Unhide® Project Also Known as The Unhide® Solve Together Unified Platform

Run by Brain Inflammation Collaborative · NCT04806620 · Data updated 2026-11-12

This study is trying to collect health information from adults with ME/CFS and Long Covid to help researchers better understand these conditions and improve future treatments.

Quick facts

Study typeObservational
Ages2 Years and up
SexAll
Enrollment10000 (estimated)
SponsorBrain Inflammation Collaborative
Academic / other
Locations1 site (Delafield, Wisconsin)
StatusRecruiting
StartedJuly 5, 2023
Main results expectedJune 30, 2030
Study endsDecember 31, 2030
Registry record updatedJanuary 22, 2026
Trial IDNCT04806620 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals aged 18 and older with ME/CFS, Long Covid, or those without these conditions who wish to contribute to research.

Probably not a fit

Patients who are under 18 or do not have ME/CFS or Long Covid may not receive direct benefits from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Solve Together is an observational platform designed to gather clinical data on post-infectious diseases, particularly Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long Covid. Participants aged 18 and older can create profiles, complete surveys about their medical history and symptoms, and use a mobile app to track their health. The collected data will be anonymized and made available to researchers to enhance understanding of these conditions and support future clinical studies. This initiative aims to foster collaboration among patients, healthcare providers, and researchers.

Why it matters

Potential benefit: If successful, this platform could significantly enhance the understanding and treatment options for patients suffering from ME/CFS and Long Covid.

How similar studies have gone: While similar data collection approaches have been utilized, this specific platform is a novel initiative aimed at addressing the unique challenges of ME/CFS and Long Covid.

Who can join: the full rules

Show full inclusion / exclusion criteria
Participants may be either self-diagnosed, or diagnosed by a physician with the following conditions:

* Infection-associated chronic conditions such as Long COVID, chronic Lyme, myalgic encephalomyelitis (ME/CFS), and post-acute neuropsychiatric syndrome (PANS/PANDAS).
* Neuroimmune, developmental, autonomic, and neurological conditions like migraines, dysautonomia, POTS, multiple sclerosis, and autism spectrum disorder.
* Autoimmune diseases such as Lupus, Sjogren's Disease, rheumatoid arthritis, myasthenia gravis, ankylosing spondylitis, and related autoimmune conditions.

Inflammatory gastrointestinal conditions such as Crohn's Disease, Celiac Disease, and ulcerative colitis.

* Behavioral and mood disorders such as anxiety, depression, bipolar disorder, PTSD, eating disorders, OCD, and other related conditions.
* "Healthy" people (without brain inflammation), including unaffected individuals, unaffected individuals in the same household, and unaffected individuals who are married to relatives and family members.
* Have consistent internet access and a cell phone, tablet, or PC since this is an online or app-based platform that requires entering data and completing surveys.
* Currently live in the United States
* Be able to participate in English (stay tuned for updates about the Spanish language version)
* Be willing to share symptom and health data through the platform

Where it's running

  • Brain Inflammation Collaborative
    Delafield, Wisconsin, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Whole-body Cryotherapy for Fatigue in ME/CFS, Fibromyalgia, Long COVID

    This study tests whether brief, repeated exposure to extreme cold can help reduce fatigue and related symptoms in adults with ME/CFS, fibromyalgia, or Long COVID compared to healthy controls.

    Recruiting Oxford Brookes University · Oxford, Oxon · NCT07874217

  • Cognitive evaluation for people with eating disorders

    This project tests whether thinking skills (like cognitive flexibility and inhibitory control) and automatic food-related attitudes differ among people aged 14–65 with ARFID, anorexia, or bulimia.

    Recruiting at 3 sites Istituti Clinici Scientifici Maugeri SpA · Pavia, PV and 2 other locations · NCT07478510

  • Using deep rTMS to improve memory in Alzheimer's Disease

    This study is testing if a new brain treatment called deep rTMS can help improve memory in people with mild to moderate Alzheimer's Disease.

    Recruiting Phase 1/2 University of California, Los Angeles · Los Angeles, California · NCT06597942

  • Genetic study on eating disorders

    This study is trying to understand the genetic and environmental causes of eating disorders by gathering information from 20,000 people with different eating disorders and healthy individuals.

    Recruiting at 5 sites University of North Carolina, Chapel Hill · Chapel Hill, North Carolina and 4 other locations · NCT06594913

  • Identifying biomarkers for autoimmune diseases affecting the nervous system

    This study is trying to find specific markers in the blood of people with autoimmune diseases affecting the nervous system, like Multiple Sclerosis, to help with early diagnosis and better treatment options.

    Recruiting Tongji Hospital · Wuhan · NCT06502015

  • Immune signals and regulatory T cells in migraine

    This research will test whether blood immune markers and regulatory T cells are linked to migraine in women ages 18–50 who have migraine or certain autoimmune/inflammatory conditions.

    Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand, AURA · NCT06426316

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.