18F-FAPI PET to detect intestinal lesions and measure IBD activity

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study enrolls adults with a confirmed diagnosis of IBD who undergo 18F-FAPI PET/CT, colonoscopy, and enhanced abdominal CT within one week so imaging and endoscopic findings can be directly compared. Investigators will match intestinal segments across modalities to determine how well FAPI PET identifies lesions and correlates with clinical disease activity. Poor-quality images and contraindications to endoscopy or CT are exclusion criteria. Participants will be followed for 12 months for major adverse outcomes to explore whether baseline imaging predicts clinical course.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients diagnosed with IBD according to clinical, imaging, endoscopic, and histopathological criteria;
* Patients ≥18 years old;
* 18F-FAPI PET/CT intestinal imaging, conventional endoscopic and enhanced CT were performed within 1 week;
* Intestinal segment matching was evaluated by endoscopy and imaging;
* Patients voluntarily participate and sign informed consent.

Exclusion Criteria:

* Pregnant or lactating patients;
* Imaging images are of poor quality and cannot be used for diagnosis and evaluation;
* Patients with contraindications for endoscopic or CT examination.

Where it's running

• Army Medical Center of PLA, Daping Hospital, Army Medical University
  Chongqing, Chongqing Municipality, China Recruiting

Study contacts

• Study coordinator: Wenbo Li, postgraduate
• Email: lwb@tmmu.edu.cn
• Phone: +8615292886778

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.