Condition

Hysterectomy clinical trials and research

• 17Clinical trials
• 9NIH research projects
• 1New in 30 days
• 11Countries

Newest Hysterectomy clinical trials

All recruiting trials (17)

• Predictors of Success and Failure of v-NOTES Hysterectomy for Large Uteri

  This study looks at which factors predict whether a v-NOTES hysterectomy for large uteri will be completed without needing to switch to another surgical approach.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07895953

• Hybrid robotic surgery for gynecologic procedures using ROB platform

  This study tests whether the ROB robotic platform and its endoscopic instruments can be safely used to perform laparoscopic hysterectomy with or without removal of tubes and/or ovaries in adult women.

  Recruiting Rob Surgical Systems S.L. · Inca, Balearic Islands and 1 other locations · NCT07832539

• Biofeedback-Assisted Pelvic Floor Training After Hysterectomy

  This study tests whether biofeedback-guided pelvic floor exercises after hysterectomy can improve pelvic floor strength, reduce urinary leakage, lessen genital prolapse, and boost quality of life.

  Recruiting Kafrelsheikh University · Kafr ash Shaykh, Kafrelsheikh · NCT07784465

• Effectiveness of M-TAPA nerve block for pain relief after laparoscopic hysterectomy

  This study tests whether the M-TAPA nerve block before surgery can reduce opioid use and pain after laparoscopic hysterectomy compared with standard pain care.

  Recruiting Istinye University · Istanbul · NCT07483190

• Reading a personal narrative book to help emotional regulation before hysterectomy in young women

  This trial tests whether reading a personal narrative book in addition to usual care can help young women preparing for hysterectomy feel calmer and less anxious or depressed.

  Recruiting at 4 sites Groupe SantéCité SantéCité Enseignement-Recherche-Innovation (GCS SCERI) · Bordeaux and 3 other locations · NCT07430488

• vNOTE Hysterectomy with Uterosacral Suspension to Support Pelvic Organs

  This study tests a vaginal natural orifice surgery technique for hysterectomy that includes upfront uterosacral suspension to help prevent pelvic organ prolapse.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07413861

• Preoperative counseling on keeping or removing ovaries for transmasculine people having hysterectomy

  This tests whether a short educational handout given before the first surgical visit helps transmasculine and non-binary people decide about keeping or removing their ovaries when having a hysterectomy.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT07324967

• Same-day discharge after robotic-assisted hysterectomy

  This will see if people having robotic-assisted hysterectomy for benign conditions or endometrial cancer can safely go home the same day instead of staying overnight.

  Recruiting at 3 sites Karolinska Institutet · Stockholm and 2 other locations · NCT07233811

• Minimally invasive versus open radical hysterectomy for early-stage cervical cancer

  This project tests whether laparoscopic (minimally invasive) radical hysterectomy works as well as open abdominal radical hysterectomy for adult women with early-stage cervical cancer who have negative sentinel lymph nodes.

  Recruiting at 3 sites Medical University of Silesia · Bialystok and 4 other locations · NCT07120529

• How genetic differences affect nalbuphine pain relief after abdominal or pelvic surgery

  We will test whether genetic differences change how well nalbuphine relieves pain after abdominal or pelvic surgery in adults.

  Recruiting Phase 2/3 Ziauddin University · Karachi, Sindh · NCT06996561

• Topical estrogen cream to improve recovery for transgender men after hysterectomy

  This study tests if using a special estrogen cream after surgery can help transgender men recover better and feel more comfortable after a hysterectomy.

  Recruiting Phase 3 Women and Infants Hospital of Rhode Island · Providence, Rhode Island · NCT06969326

• Local anesthetic injection to reduce pain after hysterectomy

  This study tests if injecting a local anesthetic into the vaginal cuff during a hysterectomy can help reduce pain after surgery and lower the need for pain medication for patients having the procedure for non-cancerous reasons.

  Recruiting Phase 4 MediSys Health Network · Flushing, New York · NCT06719180

• Stanford program to advance robotic surgery for children and adolescents

  This program will try the da Vinci Xi surgical robot in children and adolescents (ages 6–21, ≥15 kg) to see if it is safe and works well for procedures like sleeve gastrectomy, cholecystectomy, splenectomy, hysterectomy, and operations for endometriosis.

  Recruiting Stanford University · Stanford, California · NCT06671639

• Using azithromycin before hysterectomy to reduce infections

  This study is testing if giving women azithromycin before a hysterectomy can help reduce the chance of getting infections after the surgery.

  Recruiting at 6 sites Helsinki University Central Hospital · Helsinki and 5 other locations · NCT05337566

• Comparing two types of hysterectomy procedures

  This study is testing whether a new type of vaginal hysterectomy can help women recover faster and have fewer complications compared to the traditional method.

  Recruiting Zuyderland Medisch Centrum · Eindhoven, North Brabant and 1 other locations · NCT04886791

• Infusion of pain relief medication after minimally invasive hysterectomy

  This study is testing if a continuous infusion of pain relief medication can help women feel less pain after having a minimally invasive hysterectomy compared to a placebo.

  Recruiting at 2 sites Phase 4 George Washington University · Washington D.C., District of Columbia and 1 other locations · NCT04130464

• Evaluating factors related to chronic pain after hysterectomy

  This study is trying to find out what factors might lead to chronic pain after a hysterectomy in women, by looking at things like anxiety and how they feel about pain before and after the surgery.

  Recruiting KK Women's and Children's Hospital · Singapore · NCT04014829

NIH-funded research (9)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Prognostic tools to guide adjuvant therapy for Black women after hysterectomy for endometrial cancer

  A new project aims to create and validate easy-to-use tools that help doctors tailor post-surgery treatment for Black women with endometrial cancer.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11595422

• A safe, fast, and lower-cost way to remove large uterus tissue during minimally invasive hysterectomy

  A new device called the Claria System aims to remove large uteruses quickly and safely during minimally invasive hysterectomy and other surgeries, while reducing costs.

  NIH research Claria Medical, INC. · Mountain View, UNITED STATES · NIH-11416770

• A safer, faster tissue removal system for laparoscopic hysterectomy

  A new containment and extraction system for removing large uteri during laparoscopic hysterectomy is being tested to see if it’s safer and faster than current methods.

  NIH research Claria Medical, INC. · Mountain View, UNITED STATES · NIH-11314291

• Zip-stitch for laparoscopic hysterectomy

  A new Zip-stitch wound-closure system is being tested in people to make vaginal cuff closure after laparoscopic hysterectomy faster, simpler, and safer.

  NIH research Zsx Medical, LLC · Philadelphia, UNITED STATES · NIH-11305976

• A safer, faster, and more affordable way to remove large uteri during minimally invasive surgery

  A new surgical device to help surgeons remove large uteri quickly and safely during minimally invasive hysterectomy and similar operations, reducing the chance of spreading hidden cancer.

  NIH research Claria Medical, INC. · Mountain View, UNITED STATES · NIH-11256396

• A new method for closing surgical wounds after laparoscopic hysterectomy

  This study is testing a new way to close wounds after laparoscopic hysterectomy using a special system called Zip-stitch, which uses dissolvable clips to help you heal better and recover faster, with input from surgeons to make it even better for future use.

  NIH research Zsx Medical, LLC · Philadelphia, UNITED STATES · NIH-11068352

• Creating tools to predict outcomes for Black women with endometrial cancer after surgery

  This study is working to create helpful tools for doctors to better understand and treat Black women with endometrial cancer after surgery, aiming to improve their care and outcomes by considering their unique needs and risks.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11035802

• Exploring non-surgical options for managing placenta accreta spectrum.

  This study is looking at safer ways to manage placenta accreta spectrum, a serious pregnancy condition, so that women can keep their uterus and have better outcomes, and it’s led by Dr. Brett Einerson and his team who want to understand what matters most to patients during this process.

  NIH research University of Utah · Salt Lake City, United States · NIH-10892662

• A new method for safely removing tissue during minimally invasive surgeries.

  This study is working on a new, safer way to remove tissue during minimally invasive surgeries like hysterectomy, to help prevent any hidden cancers from spreading and make the whole process quicker and easier for patients.

  NIH research Claria Medical, INC. · Mountain View, UNITED STATES · NIH-10693810

Related topics

Quick answers

How many Hysterectomy clinical trials are recruiting right now?

17, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (6 trials), France (2 trials), Pakistan (1 trial), Turkey (Türkiye) (1 trial), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 2/3: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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