Local anesthetic injection to reduce pain after hysterectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of injecting a local anesthetic, Bupivacaine with epinephrine, into the vaginal cuff before closing after a total laparoscopic hysterectomy. The aim is to assess whether this intervention can lead to reduced immediate postoperative pain and lower the need for pain medication, thereby enhancing patient comfort and satisfaction. The study will compare outcomes between patients receiving the anesthetic and those receiving a saline placebo. It targets patients undergoing hysterectomy for benign conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients 18 years and older requiring total laparoscopic hysterectomy with or without bilateral salpingo-oophorectomy for benign conditions
* Presence of malignancy

Exclusion Criteria:

* Conversion to laparotomy

  * Previous multiple abdominal and/or pelvic surgeries
  * Significant medical comorbidities or cardiac history
  * Poor initial Aldrete score4 (\<10)
  * Significant pre-op pain medication use
  * Contraindication to any medication that would be used in the study (Bupivacaine, epinephrine, tramadol or oxycodone)

Where it's running

• Flushing Hospital Medical Center
  Flushing, New York, United States Recruiting

Study contacts

• Study coordinator: Hosam Hanna, MD
• Email: hhanna@jhmc.org
• Phone: (718) 670-5571

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Predictors of Success and Failure of v-NOTES Hysterectomy for Large Uteri

  This study looks at which factors predict whether a v-NOTES hysterectomy for large uteri will be completed without needing to switch to another surgical approach.

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• Hybrid robotic surgery for gynecologic procedures using ROB platform

  This study tests whether the ROB robotic platform and its endoscopic instruments can be safely used to perform laparoscopic hysterectomy with or without removal of tubes and/or ovaries in adult women.

  Recruiting Rob Surgical Systems S.L. · Inca, Balearic Islands and 1 other locations · NCT07832539

• Biofeedback-Assisted Pelvic Floor Training After Hysterectomy

  This study tests whether biofeedback-guided pelvic floor exercises after hysterectomy can improve pelvic floor strength, reduce urinary leakage, lessen genital prolapse, and boost quality of life.

  Recruiting Kafrelsheikh University · Kafr ash Shaykh, Kafrelsheikh · NCT07784465

• Postoperative tizanidine addition after pelvic reconstructive surgery

  This study tests whether adding tizanidine to the usual postoperative pain plan helps adult women recover better after urogynecologic pelvic reconstructive surgery.

  Recruiting Phase 2 Hartford Hospital · Hartford, Connecticut · NCT07766837

• Combined PECS II and PIP blocks vs TPVB for post-mastectomy pain relief

  This trial tests whether a combination of PECS II and superficial PIP blocks can provide better or similar pain relief after mastectomy compared with the standard thoracic paravertebral block.

  Recruiting Dharmais National Cancer Center Hospital · Jakarta, DKI Jakarta · NCT07738770

• Low vs. standard volume EXORA block for pain control in laparoscopic gallbladder surgery

  This trial tests whether a smaller amount of local anesthetic given as a bilateral EXORA block provides pain relief after laparoscopic cholecystectomy.

  Recruiting Fayoum University Hospital · El Fayoum Qesm, Faiyum Governorate · NCT07507799

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.