Creating tools to predict outcomes for Black women with endometrial cancer after surgery
Official title: Developing and Validating Prognostic Models for Black women with Endometrial Cancer following Hysterectomy
Funded at Sloan-Kettering Inst Can Research · NIH-11035802 · Data updated 2026-11-12
This study is working to create helpful tools for doctors to better understand and treat Black women with endometrial cancer after surgery, aiming to improve their care and outcomes by considering their unique needs and risks.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | February 13, 2025 |
| Project end | January 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $132,825 |
| NIH project number | 1K99CA297013-01 |
| Project ID | NIH-11035802 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Black women who have been diagnosed with endometrial cancer and have undergone a hysterectomy.
✕Less likely to help
Patients who do not identify as Black or who have not been diagnosed with endometrial cancer may not receive benefits from this research.
What this research studies
This research focuses on developing and validating prognostic models specifically for Black women diagnosed with endometrial cancer following hysterectomy. It aims to address the significant disparities in cancer outcomes by creating tools that help healthcare providers tailor adjuvant therapies based on individual prognosis and recurrence risks. The study will utilize clinical and epidemiological data to build these models, which will be validated through external testing. By improving decision-making in treatment options, this research seeks to enhance the care and outcomes for this underserved population.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for Black women with endometrial cancer, ultimately improving survival rates.
How similar studies have gone: Other research has shown success in developing prognostic tools for various cancer populations, indicating a promising potential for this approach in addressing health disparities.
Where this research is happening
-
Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Peeri, Noah Charles — Sloan-Kettering Inst Can Research
- Study coordinator: Peeri, Noah Charles
Related research
Other NIH-funded projects on the same topics.
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Prognostic tools to guide adjuvant therapy for Black women after hysterectomy for endometrial cancer
A new project aims to create and validate easy-to-use tools that help doctors tailor post-surgery treatment for Black women with endometrial cancer.
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Understanding why guideline-concordant endometrial cancer treatment varies in high-risk groups
This project looks at why some patients with endometrial cancer don’t receive care that follows national guidelines, aiming to find ways to ensure more patients get the best-supported treatments.
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Targeting hormone resistance to prevent endometrial cancer
Aims to boost progesterone’s cancer-preventing effect in the lining of the uterus to stop cancer from developing in people at risk, especially those who are obese or young.
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Inhibiting AXL to Improve Treatment Response in Endometrial Cancer
A cancer treatment study is testing whether blocking AXL with batiraxcept together with standard chemotherapy can help people with certain aggressive uterine cancers respond better.
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Targeting HSPA Proteins to Help Women with Advanced or Recurrent Endometrial Cancer
Aims to test a drug called SHetA2 that may slow or stop growth of advanced endometrial cancer by targeting cancer-friendlier proteins, with a focus on reducing treatment toxicity.
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Endometrial Cancer SPORE: New strategies to prevent and treat endometrial cancer
A multi-institution program is testing new ways to prevent and treat endometrial cancer in people, with three linked projects and multiple cores to support translational research.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.