Effectiveness of M-TAPA nerve block for pain relief after laparoscopic hysterectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study assigns adults undergoing elective laparoscopic hysterectomy to receive either the Modified-Thoracoabdominal Nerve Block through a Perichondrial Approach (M-TAPA) with bupivacaine before surgery or standard postoperative pain management without the block. The main outcome is total morphine consumption in the first 24 hours after surgery, with secondary outcomes including pain scores, time to first analgesic request, patient satisfaction, and side effects such as nausea. Participants are adults 18 to 70 years old with ASA I–III, without significant hepatic/renal disease, coagulation disorders, or allergies to local anesthetics, and who consent to regional anesthesia. The trial is conducted at Istinye University Liv Hospital Bahcesehir in Istanbul, sponsored by Istinye University.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged between 18 and 70 years
* ASA (American Society of Anesthesiologists) physical status I, II, or III
* Scheduled for elective laparoscopic hysterectomy
* Voluntary participation with signed informed consent

Exclusion Criteria:

* Hepatic or renal disease.
* Coagulation disorders.
* Uncontrolled cardiovascular or respiratory diseases.
* Psychiatric disorders.
* History of allergy to local anesthetics.
* History of alcoholism, drug or substance abuse.
* Body Mass Index (BMI) greater than 35 kg/m2
* Refusal of the regional block procedure

Where it's running

• Istinye University Liv Hospital Bahcesehir
  Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: onur senyurt
• Email: senyurtonur@yahoo.com
• Phone: +905520265992

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.