Preoperative counseling on keeping or removing ovaries for transmasculine people having hysterectomy
Official title: A Standardized Counseling Approach to Preoperative Education in Transmasculine Individuals Receiving Gender-affirming Surgery
Run by University of Minnesota · NCT07324967 · Data updated 2026-11-12
This tests whether a short educational handout given before the first surgical visit helps transmasculine and non-binary people decide about keeping or removing their ovaries when having a hysterectomy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | University of Minnesota Academic / other |
| Locations | 1 site (Minneapolis, Minnesota) |
| Status | Recruiting |
| Started | March 12, 2026 |
| Main results expected | July 31, 2028 |
| Study ends | July 31, 2028 |
| Registry record updated | April 3, 2026 |
| Trial ID | NCT07324967 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are English-speaking transmasculine or non-binary individuals assigned female at birth, ages 18–65, who want a gender-affirming hysterectomy and have not already had their ovaries removed.
✕Probably not a fit
People who were born without ovaries or a uterus, those who have already had a bilateral oophorectomy, or non-English speakers are not expected to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-site interventional trial randomizes eligible transmasculine and non-binary adults to receive a standardized educational handout about the benefits and risks of ovary retention versus removal or to usual care prior to their initial surgical consultation. The handout is provided at the time of an initial survey and aims to standardize preoperative counseling. The intervention focuses on improving patient knowledge and decision-making around oophorectomy as part of gender-affirming hysterectomy. Participants are English-speaking people assigned female at birth, aged 18–65, seeking hysterectomy with or without oophorectomy at the University of Minnesota.
Why it matters
Potential benefit: If successful, the handout could improve patients' understanding of risks and benefits and support clearer, more informed decisions about ovary removal.
How similar studies have gone: Educational handouts and standardized preoperative counseling have improved patient knowledge and decision quality in other surgical settings, but applying this approach specifically to oophorectomy decisions in transmasculine care is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Any transgender or non-binary individual * Age 18-65 * Assigned female at birth who desires a gender-affirming hysterectomy with or without oophorectomy * English-speaking Exclusion Criteria: * Non-transgender individuals * Any transgender individual who has already had a bilateral oophorectomy * Any transgender person who was born without ovaries or a uterus * Non-English speaking
Where it's running
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University of Minnesota
Minneapolis, Minnesota, United States Recruiting
Study contacts
- Principal investigator: Andrea Johnson — University of Minnesota
- Study coordinator: Erin Wesley
- Email: obgynresearch@umn.edu
- Phone: 612-624-9208
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.