Condition

Gingivitis clinical trials and research

• 31Clinical trials
• 1New in 30 days
• 15Countries

Newest Gingivitis clinical trials

All recruiting trials (31)

• High BMI and periodontitis in Thai adults under 60

  This study tests how common high BMI and periodontitis are among Thai adults aged 18–59 and what factors are linked to them.

  Recruiting Mahidol University · Bangkok, Ratchathewi · NCT07880717

• Toothpaste for reducing dental plaque and preventing gum problems

  This study tests three toothpaste options to see if they reduce plaque and gingivitis in adults with mild gum inflammation.

  Recruiting Phase 3 Colgate Palmolive · Roma, Rome · NCT07842991

• Effect of stannous fluoride toothpaste on gingival health indicators in an experimental gingivitis model

  This study tests whether a toothpaste with stannous fluoride can influence gingival crevicular fluid biomarkers and help gingival tissue recover during early gingivitis.

  Recruiting Haleon · Birmingham · NCT07842042

• Toothpaste that may reduce plaque and gingivitis in Chinese adults

  A toothpaste test will be used to see if it reduces plaque and gingivitis more than a regular fluoride toothpaste in Chinese people with localized gingivitis.

  Recruiting Haleon · Shanghai, Shanghai Municipality · NCT07816406

• Safety and effectiveness of an electric flosser with a manual toothbrush for gingivitis and plaque

  This study tests whether using an electric interproximal flosser in addition to a manual toothbrush can reduce gingival inflammation and plaque in adults with gingivitis compared with brushing alone.

  Recruiting Flaus, Inc · Fort Wayne, Indiana · NCT07779564

• Bacterial Diversity in Gum Health With Fixed vs Removable Retainers After Braces

  This study tests the gum microbiome and gum health in adults after braces, comparing fixed lingual retainers to removable Essix retainers.

  Recruiting Universidad de Murcia · Murcia · NCT07718061

• Vitamin D and the body's anti-inflammatory response in gum disease

  This study tests whether vitamin D can modulate the body's anti-inflammatory response in people with gum disease.

  Recruiting Recep Tayyip Erdogan University Training and Research Hospital · Rize · NCT07636733

• Dental plaque and gum health study using fluoride toothpaste in adults with varying gingivitis and plaque levels

  This study tests a fluoride toothpaste to see how it affects dental plaque and gingivitis in adults with high plaque, including groups with low and high gingival inflammation.

  Recruiting Phase 4 Colgate Palmolive · Fort Wayne, Indiana · NCT07614490

• Gingivitis in kids vs young adults: comparing fluid biomarkers in the mouth

  This study will test whether gum fluid biomarkers differ between children and young adults with gingivitis.

  Recruiting Nigde Omer Halisdemir University · Niğde · NCT07607639

• Do intelligent electric toothbrushes replace professional tooth cleaning for gum inflammation?

  We will test whether using an intelligent electric toothbrush with an oral-care routine can control gum inflammation in adults with gingivitis or early periodontitis as well as adding professional tooth cleaning.

  Recruiting Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · Shanghai, Shanghai Municipality · NCT07549347

• SALI-10 probiotic lozenges for gingivitis and halitosis

  This study tests whether SALI-10 probiotic lozenges can help people with gingivitis and bad breath.

  Recruiting Ostia Sciences · Hamilton, Ontario · NCT07508839

• toothpaste for gingivitis in adults

  A toothpaste is being tested in adults with gingivitis to see if it improves gum inflammation compared with a regular toothpaste.

  Recruiting Lacer S.A. · Castelldefels, Barcelona · NCT07494747

• Xylitol Gum to Prevent Premature Birth and Protect Baby Health

  This trial tests whether chewing xylitol gum during pregnancy reduces preterm birth and improves birth outcomes for pregnant people and their babies.

  Recruiting Phase 2/3 University of Washington · Lilongwe · NCT07424846

• 6-month test of an antimicrobial mouthrinse to reduce plaque and improve gum health

  This 6-month test will see if an antimicrobial mouthrinse, used twice daily, reduces established plaque and improves gum health in adults with gingivitis.

  Recruiting Phase 4 Colgate Palmolive · Schenefeld · NCT07414173

• Online self-check to identify your gum disease risk and guide preventive care

  This project will test whether an online questionnaire can accurately identify gum disease risk in adults with natural teeth.

  Recruiting Universiti Sains Malaysia · Abhā, 'Asir Region · NCT07410351

• Non‑invasive tests using photos, X‑rays, questionnaires and saliva markers to detect gum disease

  This project will test whether photos, dental X‑rays, questionnaires, and saliva/microbial markers can accurately detect gum disease in adults seeking dental care.

  Recruiting Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · Shanghai, Shanghai Municipality and 2 other locations · NCT07406867

• Oral Health Care During Pregnancy to Try to Improve Gum Health and Birth Outcomes

  This study tests two noninvasive ways to improve dental health for pregnant people with gum disease, to see if better oral care can help pregnancy outcomes.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07377344

• Pure green tea mouthwash versus placebo and essential-oil rinses for plaque and gum inflammation

  This trial will see if rinsing twice daily with a pure green tea mouthwash reduces dental plaque and gum inflammation in healthy adults compared with placebo and two commercial mouthwashes.

  Recruiting King Abdullah University Hospital · Irbid, Irbid Governorate · NCT07364565

• Blood and saliva markers to track gum disease and healing after non-surgical cleaning

  This project tries to see if a blood score (HALP), other blood inflammation markers, and salivary MMP-8 can help identify gum disease stage and predict healing after non-surgical periodontal cleaning in adults aged 18–65.

  Recruiting Erzincan University · Merkez, Erzincan · NCT07312045

• OROXID® oral solution for treating gingivitis

  This test checks whether OROXID® oral solution (forte or sensitive) helps reduce gum inflammation and bleeding in adults with gingivitis.

  Recruiting at 2 sites ENIKAM d.o.o. · Ljubljana and 1 other locations · NCT07270705

• Lactoferrin oral care to improve gum health during pregnancy

  This will test whether adding a lactoferrin mouthwash to lactoferrin toothpaste plus regular professional cleanings improves gum health in pregnant women 14–28 weeks into pregnancy.

  Recruiting University of Pavia · Pavia, Lombardy · NCT07069140

• Coenzyme Q10 toothpaste with daily Limosilactobacillus reuteri probiotics to improve gum health during pregnancy

  For pregnant women with gum disease, this will try whether adding a CoQ10 toothpaste and daily L. reuteri probiotic to regular cleanings reduces plaque and gum bleeding.

  Recruiting University of Pavia · Pavia, Lombardy · NCT07029360

• Examining Salivary Cytokine Levels in Different Periodontal Conditions

  This study is trying to see if the levels of certain proteins in saliva can help us understand the differences in gum health between people with healthy gums, gingivitis, and periodontitis.

  Recruiting Izmir Katip Celebi University · Izmir, Çiğli · NCT06961409

• Improving dental care for nursing home residents to reduce infections and enhance diabetes control

  This study tests if better dental care for nursing home residents can help reduce infections and improve diabetes control.

  Recruiting Missouri Department of Health and Senior Services · Jefferson City, Missouri · NCT06890676

• Using a special mouthrinse to treat gingivitis in adolescents at home

  This study is testing whether a special mouthrinse can help teenagers with gingivitis improve their gum health when used along with regular brushing and flossing at home.

  Recruiting Università degli Studi di Ferrara · Ferrara · NCT06671106

• Using ultra-high frequency ultrasound to study gum tissue in healthy individuals and those with gingivitis

  This study is testing how ultra-high frequency ultrasound can help us see the differences in gum tissue between healthy people and those with gingivitis.

  Recruiting at 2 sites University of Pisa · Pisa, Italy and 1 other locations · NCT06480825

• Comparing electric and manual toothbrushes for orthodontic patients after oral surgery

  This study tests whether an electric toothbrush works better than a manual toothbrush for improving gum health in orthodontic patients who have had oral surgery.

  Recruiting Children's Hospital Los Angeles · Los Angeles, California · NCT06122805

• Using intraoral scanners to diagnose dental and periodontal diseases

  This study tests whether using a special 3D scanner can help dentists diagnose tooth and gum diseases more accurately and quickly than traditional methods for patients with gum issues.

  Recruiting CHU de Reims · Reims · NCT06006429

• Health education interventions to prevent dental issues in orthodontic patients

  This study tests two different ways of teaching young people with braces about oral health to see which one helps them avoid cavities and gum disease better.

  Recruiting Universidad Nacional de Colombia · Bogotá · NCT05979805

• Comparing Novosyn and Monosyn sutures in gum surgery

  This study is testing if two types of stitches used in gum surgery help wounds heal just as well in adults.

  Recruiting Aesculap AG · Sant Cugat del Vallès, Catalonia · NCT05813236

• Assessing Oral Health Using Imaging and Products

  This study is testing whether using certain toothpastes and mouthwashes can improve gum health and oral hygiene by tracking changes in plaque levels and gum condition over time.

  Recruiting University of California, Irvine · Irvine, California · NCT05470023

Related topics

Quick answers

How many Gingivitis clinical trials are recruiting right now?

31, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 15 countries. The most sites are in Italy (6 trials), United States (6 trials), Turkey (Türkiye) (4 trials), China (3 trials), Spain (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 3: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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