Using ultra-high frequency ultrasound to study gum tissue in healthy individuals and those with gingivitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to compare the clinical aspects of gingival tissue between healthy individuals and patients suffering from gingivitis. Participants will undergo ultra-high frequency ultrasonographic scans to assess various parameters of gingival tissue, including thickness, echogenicity, and vascularization. The study will enroll both healthy controls and patients with gingivitis, focusing on the ultrastructural variations associated with inflammation. The scans will be performed on three areas of the dental arch to gather comprehensive data.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* males or females of age \> 18 years
* presence of at least 20 teeth
* full-mouth plaque score (FMPS) \>50%
* FMBS \>30%
* ability and willingness to give informed consent

Exclusion Criteria:

* pregnancy or breastfeeding
* pharmacological treatment with antinflammatory drugs, statins, or either local or systemic antibiotics (within the previous 30 days)
* smoking habit
* dental or periodontal condition requiring immediate treatment
* refusal to be enrolled in the study

Where it's running

• University of Pisa
  Pisa, Italy, Italy Recruiting
• Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University Hospital of Pisa
  Pisa, Italy Recruiting

Study contacts

• Study coordinator: Rossana Izzetti
• Email: rossana.izzetti@unipi.it
• Phone: 3475205619

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.