Assessing Oral Health Using Imaging and Products
Official title: Imaging-based Assessment of Oral Biofilm and Gingival Health
Run by University of California, Irvine · NCT05470023 · Data updated 2026-11-12
This study is testing whether using certain toothpastes and mouthwashes can improve gum health and oral hygiene by tracking changes in plaque levels and gum condition over time.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 275 (estimated) |
| Sponsor | University of California, Irvine Academic / other |
| Locations | 1 site (Irvine, California) |
| Status | Recruiting |
| Started | September 1, 2022 |
| Main results expected | December 2028 |
| Study ends | December 2028 |
| Registry record updated | December 23, 2025 |
| Trial ID | NCT05470023 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who are in good general health.
✕Probably not a fit
Patients with a history of allergies or intolerances to oral hygiene products may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to improve the measurement of oral health by utilizing photographs and imaging software to assess plaque levels and gum health. Participants will use specific over-the-counter toothpastes or mouthwashes for a duration of 7 days to 6 months, while their oral health metrics will be evaluated through clinical exams and imaging. The goal is to determine the effectiveness of these products on improving gum health and overall oral hygiene. Participants will be trained in proper brushing techniques and will adhere to specific oral care protocols throughout the study.
Why it matters
Potential benefit: If successful, this study could lead to better assessment methods for oral health and improved recommendations for dental care products.
How similar studies have gone: While similar studies have explored oral health assessments, this specific approach using imaging and product comparison is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * At least 18 years of age or older * In good general health Exclusion Criteria: * History of allergy or intolerance of oral hygiene products such as toothpastes and mouthrinses
Where it's running
-
Beckman Laser Institute and Medical Clinic
Irvine, California, United States Recruiting
Study contacts
- Principal investigator: Dr. Petra Wilder-Smith — Beckman Laser Institute University of California Irvine
- Study coordinator: Dr. Petra Wilder-Smith
- Email: pwsmith@uci.edu
- Phone: 949-824-7632
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
High BMI and periodontitis in Thai adults under 60
This study tests how common high BMI and periodontitis are among Thai adults aged 18–59 and what factors are linked to them.
-
Toothpaste for reducing dental plaque and preventing gum problems
This study tests three toothpaste options to see if they reduce plaque and gingivitis in adults with mild gum inflammation.
-
Effect of stannous fluoride toothpaste on gingival health indicators in an experimental gingivitis model
This study tests whether a toothpaste with stannous fluoride can influence gingival crevicular fluid biomarkers and help gingival tissue recover during early gingivitis.
-
Toothpaste that may reduce plaque and gingivitis in Chinese adults
A toothpaste test will be used to see if it reduces plaque and gingivitis more than a regular fluoride toothpaste in Chinese people with localized gingivitis.
-
Safety and effectiveness of an electric flosser with a manual toothbrush for gingivitis and plaque
This study tests whether using an electric interproximal flosser in addition to a manual toothbrush can reduce gingival inflammation and plaque in adults with gingivitis compared with brushing alone.
-
Bacterial Diversity in Gum Health With Fixed vs Removable Retainers After Braces
This study tests the gum microbiome and gum health in adults after braces, comparing fixed lingual retainers to removable Essix retainers.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.