Pure green tea mouthwash versus placebo and essential-oil rinses for plaque and gum inflammation
Official title: The Antiplaque and Antigingivitis Effect of Pure Green Tea Mouth Wash Compared to Placebo and Essential Oils Mouth Washes: A Double Blinded Randomized Controlled Clinical Trial.
Run by King Abdullah University Hospital · NCT07364565 · Data updated 2026-11-12
This trial will see if rinsing twice daily with a pure green tea mouthwash reduces dental plaque and gum inflammation in healthy adults compared with placebo and two commercial mouthwashes.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 44 (estimated) |
| Sponsor | King Abdullah University Hospital Academic / other |
| Locations | 1 site (Irbid, Irbid Governorate) |
| Status | Recruiting |
| Started | December 1, 2025 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | January 23, 2026 |
| Trial ID | NCT07364565 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy non-smokers aged 18–50 with at least 24 teeth and no periodontal pockets >3 mm who are willing to refrain from mechanical oral hygiene for three weeks and attend scheduled clinic visits.
✕Probably not a fit
Patients who smoke, are medically compromised or pregnant, have active caries, significant restorations or orthodontic retainers, allergies to green tea or essential oils, or existing periodontal disease are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a double-blinded, randomized, parallel-group trial comparing four mouthrinses: pure green tea, Listerine Total Care, Listerine Green Tea, and a flavored placebo. Healthy non-smoking adults aged 18–50 who meet periodontal-health criteria will stop mechanical oral hygiene and rinse with 10 ml of their assigned mouthwash for 30 seconds twice daily over a three-week experimental gingivitis period. Clinical outcomes (plaque index, gingival index, staining index) and patient-reported freshness/bad-breath ratings will be collected at baseline and on days 7, 14, and 21. The study plans to enroll 44 participants (11 per group) to detect modest differences between groups with 80% power.
Why it matters
Potential benefit: If successful, the green tea mouthwash could offer a natural, low-cost option to help reduce plaque and gum inflammation similar to commercial essential-oil rinses.
How similar studies have gone: Laboratory studies and small clinical trials have suggested green tea extracts can reduce plaque and gingival inflammation, while essential-oil mouthwashes like Listerine have established efficacy, but direct head-to-head comparisons with pure green tea are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * Non-smokers * Systemically healthy * At least 24 teeth in the functional dentition, excluding third molars * Clinical diagnosis of periodontal health (no periodontal pockets \> 3 mm, bleeding on probing percentage \< 10%, and no attachment loss). Exclusion criteria: * Smokers. * Medically compromised patients. * Pregnant woman. * Allergies to green tea or EO. * Any condition that might affect the periodontal tissues. * Patients with any carious lesions (initial or active). * Patients who have overhang restorations, poorly designed crowns or bridges, and ortho retainers. * Use of systemic antibiotics or anti-inflammatory medications within 3 months prior to enrolment.
Where it's running
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Jordan University of Science and Technology, Faculty of Dentistry
Irbid, Irbid Governorate, Jordan Recruiting
Study contacts
- Principal investigator: Dana Abdullah, MClinDent Perio — Jordan University of Science and Technology
- Study coordinator: Lana Bader, DClinDent Perio
- Email: lmbader4@just.edu.jo
- Phone: +962791200956
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.