Registry for assessing QFR analysis in coronary artery disease

Institute for Cardiovascular Diseases "Dedinje" Fractional Flow Reserve (FFR) and Quantitative Flow Ratio (QFR) Registry

Institute for Cardiovascular Diseases Dedinje · NCT06659367

This study is testing if a new method called QFR for checking blood flow in heart arteries can be used effectively by less experienced doctors during routine procedures for patients with coronary artery disease.

Quick facts

Study typeObservational
Enrollment2500 (estimated)
Ages18 Years and up
SexAll
SponsorInstitute for Cardiovascular Diseases Dedinje (other)
Locations1 site (Belgrade)
Trial IDNCT06659367 on ClinicalTrials.gov

What this trial studies

This registry aims to evaluate the feasibility and diagnostic performance of Quantitative Flow Ratio (QFR) analysis conducted by inexperienced medical users in a real-world setting, using Fractional Flow Reserve (FFR) as the gold standard. The study will include patients over 18 years old who undergo clinically indicated FFR procedures at the Institute for Cardiovascular Diseases 'Dedinje'. The focus is on understanding how well QFR can be performed outside of specialized core labs, particularly by those with limited experience. The findings could provide insights into the reliability of QFR in everyday clinical practice.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old who are undergoing clinically indicated FFR procedures.

Not a fit: Patients who decline to participate and provide informed consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the diagnostic accuracy of coronary artery disease assessments in clinical settings.

How similar studies have performed: Previous studies have shown promising results for QFR analysis, but this registry focuses on its application by inexperienced users, making it a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* \>18 years old
* Had a clinically indicated FFR procedure performed (either as a planned procedure or ad hoc)

Exclusion Criteria:

* Declines to participate in the registry and provide informed consent

Where this trial is running

Belgrade

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Coronary Artery Disease, Fractional Flow Reserve, coronary artery disease, fractional flow reserve, quantitative flow ratio, FFR, QFR

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.