Assessing heart disease risk in former NFL players
Using CTA Measures to Define Cardiac Risk In NFL Alumni
This study looks at heart disease risk in retired NFL players by checking their heart health with special scans to see how their past as professional athletes affects them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Sex | All |
| Sponsor | HeartFlow, Inc. Industry-sponsored |
| Locations | 1 site (Greenwood Village, Colorado) |
| Trial ID | NCT06831409 on ClinicalTrials.gov |
What this trial studies
The GAMEFILM Registry is a multi-center observational study that collects data on the prevalence and severity of coronary artery disease (CAD) among retired NFL players. This study involves approximately 300 participants from around 20 sites across the United States. Participants will undergo coronary computed tomography angiography to evaluate their cardiac health and identify potential risks associated with their history as professional athletes.
Who should consider this trial
Good fit: Ideal candidates for this study are retired NFL players who have previously been on a practice squad or active roster.
Not a fit: Patients who are not retired NFL players or those whose coronary computed tomography angiography cannot be successfully processed will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the cardiac health of former NFL players, leading to better prevention and treatment strategies for heart disease.
How similar studies have performed: Other studies have explored cardiac health in athletes, but this specific focus on retired NFL players and the use of advanced imaging techniques is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Retired NFL player Exclusion Criteria: * CCTA not successfully processed for FFRct and AI-Plaque
Where this trial is running
Greenwood Village, Colorado
- Boone Heart Institute — Greenwood Village, Colorado, United States (Recruiting)
Study contacts
- Principal investigator: Jeffrey Boone — Boone Heart Institute
- Study coordinator: HeartFlow
- Email: GAMEFILM@heartflow.com
- Phone: 650-241-1221
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.