Erectile function changes after coronary stent procedures for heart attack versus stable angina

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational follow-up of men aged 30–75 who undergo successful percutaneous coronary intervention for either acute myocardial infarction or stable angina, with groups compared head-to-head. Erectile function is measured using the International Index of Erectile Function (IIEF) at baseline (post-recovery), 3 months, and 6 months, alongside Beck Depression Inventory and Fear of Cardiac Recurrence and Progression questionnaires. The study excludes patients with malignancy, major neurological causes of ED, uncontrolled diabetes (HbA1c >9%), more than two chronic systemic diseases, or chronic polypharmacy, and conducts face-to-face follow-up visits at the treating hospital. The primary aim is to test whether baseline erectile status predicts subsequent cardiac events and the secondary aim is to see whether having had a myocardial infarction versus stable angina changes erectile outcomes over time.

Why it matters

Who can join: the full rules

Inclusion Criteria

* Male patients aged 30-75 years
* Undergoing successful percutaneous coronary intervention (PCI) for one of the following:

  * Acute myocardial infarction (Group 1)
  * Stable angina (Group 2)
* Hemodynamically stable after the PCI procedure
* Survival of the index hospitalization
* Ability to provide written informed consent
* Sexually active within the 3 months prior to enrollment
* Willingness and ability to complete follow-up visits and questionnaires at:

  * Baseline (post-PCI recovery)
  * 3 months
  * 6 months Exclusion Criteria
* Known malignancy (active or recently treated)
* Neurological disorders affecting erectile function, including:

  * Spinal cord injury
  * Multiple sclerosis
  * Parkinson's disease
* Uncontrolled diabetes mellitus (HbA1c \> 9%)
* Presence of more than two chronic systemic diseases, such as:

  * Severe renal disease
  * Severe hepatic disease
  * Severe pulmonary disease
* Polypharmacy, defined as chronic use of more than three daily medications
* Absence of sexual activity or lack of a sexual partner
* Refusal or inability to provide informed consent or complete study questionnaires
* Severe psychiatric illness interfering with study participation
* Endocrine disorders, including:

  * Untreated hypogonadism
  * Thyroid disease
* Major post-PCI complications preventing participation, including:

  * Reinfarction
  * Stroke
  * Heart failure

Where it's running

• The Hospital of Kirikkale Univerity Faculty of Medicine
  Kirikkale, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Timucin Sipal, Assistan Prof — Kirikkale Univerity faculty of medicine department of Urology
• Study coordinator: Timucin Sipal, MD, PhD
• Email: drtimucin@hotmail.com
• Phone: +905338170659

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.