Condition
Acute Coronary Syndromes (ACS) clinical trials and research
As of November 12, 2026, Find a Trial lists 18 Acute Coronary Syndromes (ACS) clinical trials that are recruiting, at sites in 11 countries (most in China (5), Netherlands (2), South Korea (2)). By phase: Phase 4 (3), Phase 3 (1), Phase 1 (1). The most active sponsors are Ruijin Hospital (2), Eunpyeong St. Mary's Hospital (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 18Clinical trials
- 11Countries
Newest Acute Coronary Syndromes (ACS) clinical trials
All recruiting trials (18)
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Risk of malignant arrhythmias after acute coronary syndrome
This study tracks how often dangerous heart rhythms occur in adults admitted for ACS and looks for patterns that might predict them.
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Drug-coated balloons vs drug-eluting stents for immediate slow-flow/no-reflow in STEMI with high thrombus
This study tests whether using a drug-coated balloon instead of a drug-eluting stent during PCI helps reduce immediate slow-flow or no-reflow in STEMI patients with high thrombus burden.
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New prodrug CG-0255 Besylate vs Plavix in healthy adults
This study tests whether CG-0255 Besylate works similarly to Plavix® in healthy adults to understand how the two drugs behave in the body.
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Biomarker patterns in ACS patients with pneumonia and COPD after flu vaccination
This study tests whether certain blood biomarkers change in people with acute coronary syndrome who also have pneumonia and COPD, and whether flu vaccination affects those biomarker levels.
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Prehospital High-Sensitivity Troponin I to rule out heart attack for EMS patients
EMS patients with chest pain or possible heart symptoms are being studied to see if a portable hs-TnI test in the ambulance can help identify those at low risk for a heart attack.
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IVUS-guided versus angiography-guided stent placement for acute coronary syndrome
This test will see if using intravascular ultrasound (IVUS) to guide stent placement helps adults with acute coronary syndrome more than standard angiography-guided PCI.
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Antithrombotic options for acute coronary syndrome with coronary artery ectasia
This trial tests whether using rivaroxaban instead of the usual aspirin plus clopidogrel better prevents clot-related complications in adults hospitalized with acute coronary syndrome who have coronary artery ectasia.
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Fexuprazan to prevent upper gastrointestinal bleeding in high-bleeding-risk patients on dual antiplatelet therapy after stent placement
This will test whether taking fexuprazan once daily for six months reduces upper gastrointestinal bleeding in people at high bleeding risk who need dual antiplatelet therapy after coronary stent placement.
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Intravenous iron to improve quality of life in older adults after acute coronary syndrome
This trial will try a single dose of intravenous ferric carboxymaltose in people 65 and older with iron deficiency after an acute coronary event to see if it improves quality of life and reduces frailty and adverse outcomes over 12 months.
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Restoring gut balance with natural and probiotic extracts for people with acute coronary syndromes
This test checks whether high-bioavailability essential oil formulations and probiotic approaches can restore healthy gut bacteria in adults aged 30–70 hospitalized with acute coronary syndromes.
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Flu vaccine after a heart attack or unstable angina
This trial will test whether giving a flu shot to adults aged 18–80 who recently had acute coronary syndrome lowers the chance of future heart attacks, stroke, or death.
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ECG-less CT angiogram for people with high-troponin chest pain
This trial will test whether an ECG-less CT angiogram can quickly rule out life-threatening causes in people who come to the ER with chest pain and elevated troponin levels.
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Drug-coated balloon treatment versus medication for fat-rich coronary plaques
This trial will test whether using a paclitaxel-coated balloon during PCI can reduce the fat content of dangerous coronary plaques in adults with acute coronary syndrome compared with standard medication alone.
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Personalized cardiac rehabilitation after an acute coronary event, focused on women and frail patients
This project will test a personalized, patient-centered cardiac rehabilitation program to see if it helps people—especially women and frail patients—recover better after an acute coronary syndrome.
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Comparing point-of-care and laboratory testing for heart attack diagnosis
This study is testing if a quick bedside test for heart attacks can help patients with chest pain leave the hospital faster than using the traditional lab tests.
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Preventive stenting for vulnerable coronary plaques in ACS patients
This trial will test whether adding a preventive percutaneous intervention to optimal medical therapy helps people with acute coronary syndrome who have non-flow-limiting vulnerable coronary plaques.
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Identifying biomarkers for high-risk coronary plaques
This study is trying to find new blood markers that can help predict dangerous heart plaque in patients with chronic heart issues or certain types of heart attacks.
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Evaluating coronary artery plaque using advanced imaging techniques
This study is testing new imaging techniques to better understand coronary artery plaque in patients with heart conditions and see if these methods can help predict serious heart problems in the future.
Related topics
Quick answers
How many Acute Coronary Syndromes (ACS) clinical trials are recruiting right now?
18, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 11 countries. The most sites are in China (5 trials), Netherlands (2 trials), South Korea (2 trials), Spain (2 trials), Italy (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 3, Phase 3: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.