Condition

Extracorporeal Membrane Oxygenation Complication clinical trials and research

• 19Clinical trials
• 16Countries

Newest Extracorporeal Membrane Oxygenation Complication clinical trials

All recruiting trials (19)

• Safety and performance of the Novalung kit and Xenios 2.0 during stationary use for patients on ECMO

  This observational study tests whether using the Novalung ultimate kit with Xenios 2.0 (and MultiSupport Ground) helps maintain blood oxygenation in adults on ECMO during hospital stay and ground transport.

  Recruiting at 3 sites Fresenius Medical Care Deutschland GmbH · Erfurt, Bavaria and 2 other locations · NCT07156669

• Using near apneic ventilation with ECMO for severe respiratory distress

  This study is testing if a new way of breathing support called near apneic ventilation can help patients with severe respiratory distress on ECMO recover better and faster than the usual care.

  Recruiting at 11 sites Phase 3 Assistance Publique - Hôpitaux de Paris · Bobigny and 10 other locations · NCT06814340

• Using cangrelor to improve outcomes in patients with cardiogenic shock on ECMO

  This study is testing if adding a medication called cangrelor can help patients in cardiogenic shock on ECMO have better outcomes while reducing bleeding risks during their treatment.

  Recruiting Phase 2 IRCCS San Raffaele · Milan, Italy · NCT06792643

• Investigating left ventricle unloading during extracorporeal life support

  This study looks at how different methods of relieving pressure on the heart can help patients on a special life support system called VA ECLS, especially those in serious heart trouble.

  Recruiting Maastricht University Medical Center · Maastricht · NCT06766006

• MiniLung petite kit for neonates and infants with severe respiratory or cardiac failure

  We will test whether the MiniLung petite kit with the Xenios console safely improves oxygenation, removes CO2, and stabilizes circulation in newborns and young infants (2–8 kg) with severe respiratory or cardiopulmonary failure.

  Recruiting at 2 sites Fresenius Medical Care Deutschland GmbH · Bonn, North Rhine-Westphalia and 1 other locations · NCT06750536

• RECOMMEND platform testing interventions for adults receiving ECMO

  This platform tests whether different treatments, such as liberal versus restrictive red blood cell transfusion strategies, help adults on ECMO survive and need less organ support and hospital resources by day 28.

  Recruiting Phase 3 Australian and New Zealand Intensive Care Research Centre · Camperdown, New South Wales and 2 other locations · NCT06526533

• Detecting brain injuries in children on ECMO using portable MRI

  This study is testing a portable MRI to see if it can help find brain injuries in children on ECMO support more quickly and accurately.

  Recruiting Children's Mercy Hospital Kansas City · Kansas City, Missouri · NCT06469801

• Nafamostat mesilate versus heparin for anticoagulation in ECMO after cardiac surgery

  This study will test whether nafamostat mesilate works better than unfractionated heparin for anticoagulation in adults on ECMO after cardiac surgery.

  Recruiting Beijing Anzhen Hospital · Beijing, Beijing Municipality · NCT06276010

• Bivalirudin versus heparin for blood thinning during ECMO

  This trial tests whether bivalirudin keeps anticoagulation closer to target and reduces clotting or bleeding compared with standard heparin in adults on VA- or VV-ECMO.

  Recruiting Beijing Anzhen Hospital · Beijing, Beijing Municipality · NCT06275555

• Comparing Bivalirudin and Heparin for Anticoagulation in ECMO Patients

  This study is testing whether Bivalirudin works better than Heparin for preventing blood clots in patients on ECMO while also checking for bleeding risks and costs.

  Recruiting Phase 2 Sydney Local Health District · Sydney, New South Wales · NCT05959252

• Monitoring leg pressure in patients on ECMO to prevent compartment syndrome

  This study is testing a new device that continuously checks leg pressure in patients on ECMO to see if it helps prevent serious leg problems better than regular methods.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT05830721

• Evaluating Red Blood Cell Transfusion in ECMO Patients

  This study is trying to find the best hemoglobin levels for red blood cell transfusions in critically ill patients on ECMO to improve their care and outcomes.

  Recruiting at 2 sites Australian and New Zealand Intensive Care Research Centre · Camperdown, New South Wales and 1 other locations · NCT05814094

• Timing of Distal Perfusion to Prevent Limb Ischemia in ECMO Patients

  This study tests whether giving a special treatment to improve blood flow in the legs right when symptoms start is better than doing it right at the beginning of heart support for patients with severe heart problems.

  Recruiting Asan Medical Center · Seoul · NCT05698628

• Evaluating new treatments for acute respiratory failure

  This study is testing new treatments for patients with severe breathing problems to see if different ventilation methods can help them survive better in the hospital.

  Recruiting at 100 sites University Health Network, Toronto · Tucson, Arizona and 102 other locations · NCT05440851

• Evaluation of the EUROSETS ECMOLIFE SYSTEM for Extracorporeal Life Support

  This study is testing the safety and performance of a new life support system in patients who need help with their heart and lungs due to serious conditions.

  Recruiting Eurosets S.r.l. · Vienna · NCT05163925

• Analyzing outcomes of extracorporeal life support after cardiac surgery

  This study looks at how extracorporeal life support helps patients with heart failure after heart surgery to see what factors affect their chances of recovery.

  Recruiting University of Florence · Florence · NCT04330651

• VV-ECMO without therapeutic blood thinners for severe respiratory failure

  This pilot trial tries running veno-venous ECMO without therapeutic anticoagulants to see if it's safe for adults with ARDS.

  Recruiting Phase 2/3 University Health Network, Toronto · Toronto, Ontario · NCT04273607

• Evaluating ECMO therapy timing for children with septic shock

  This study is testing the best timing for using ECMO therapy in children with severe septic shock to see if it can improve their treatment outcomes.

  Recruiting Children's Hospital of Fudan University · Shanghai · NCT03948048

• Transplanting patients' own mitochondria to improve heart function after ischemia

  This study is testing whether injecting children's own mitochondria into their heart can help improve heart function after a lack of blood flow during ECMO treatment.

  Recruiting Boston Children's Hospital · Boston, Massachusetts · NCT02851758

Related topics

Quick answers

How many Extracorporeal Membrane Oxygenation Complication clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in United States (4 trials), Australia (4 trials), Italy (3 trials), China (3 trials), Germany (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 2: 2, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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