Condition

Neutropenia clinical trials and research

• 13Clinical trials
• 17NIH research projects
• 28Countries

Newest Neutropenia clinical trials

All recruiting trials (13)

• Low-dose Liposomal Amphotericin B for preventing fungal infections in adults with blood cancers and prolonged neutropenia

  This study tests whether giving a daily 50 mg dose of liposomal amphotericin B can help prevent invasive fungal infections in adults with blood cancers who have prolonged low white blood cell counts.

  Recruiting Haikou Affiliated Hospital of Central South University Xiangya School of Medicine · Hainan, Hainan · NCT07763054

• Low-dose liposomal amphotericin B to prevent invasive fungal infections in neutropenic children

  This study tests whether giving a fixed low dose of liposomal amphotericin B can prevent invasive fungal infections in children aged 3–17 who are severely neutropenic after hematopoietic stem cell transplantation or similar high-risk conditions.

  Recruiting Haikou Affiliated Hospital of Central South University Xiangya School of Medicine · Haikou, Hainan · NCT07725263

• G-CSF–fusion protein to prevent chemotherapy neutropenia in children with sarcoma

  This trial tests Albipagrastim alfa (QLC2519) in children with sarcoma to see if it helps prevent chemotherapy-induced neutropenia.

  Recruiting Phase 2 Qilu Pharmaceutical Co., Ltd. · Beijing · NCT07724756

• Preventing neutropenia after cancer treatment with mecapegfilgrastim injections

  This will try mecapegfilgrastim injections to prevent low white blood cell counts (neutropenia) in adults with solid tumors getting chemotherapy, radiotherapy, or immunotherapy.

  Recruiting Hebei Medical University Fourth Hospital · Shijiazhuang, Hebei · NCT07434063

• Preventing G-CSF bone pain with diosmin-hesperidin and loratadine

  We will test whether diosmin-hesperidin, loratadine, or both can prevent bone pain from G-CSF in adults with leukemia or lymphoma.

  Recruiting Alexandria University · Alexandria · NCT07300735

• Home blood count monitoring to diagnose cyclic versus severe congenital neutropenia

  This test uses a home device called Athelas One to measure white blood cell and neutrophil counts in people with known ELANE mutations to see if daily home numbers can diagnose cyclic neutropenia and tell it apart from severe congenital neutropenia.

  Recruiting Early Phase 1 University of Washington · Seattle, Washington · NCT07066085

• Examining the NUDT15 gene's role in inflammatory bowel disease in Taiwan

  This study looks at how the NUDT15 gene affects children with inflammatory bowel disease in Taiwan to see if it can help improve their treatment.

  Recruiting National Taiwan University Hospital · Taipei · NCT06913998

• Using luspatercept to improve low blood cell counts in patients with clonal cytopenias of uncertain significance

  This study is testing if a drug called luspatercept can help people with low blood cell counts due to clonal cytopenias of uncertain significance feel better and improve their blood levels over 24 weeks.

  Recruiting Phase 2 Weill Medical College of Cornell University · New York, New York · NCT06788691

• Breath analysis to detect fungal infections in leukemia patients

  This study is testing if analyzing breath samples can help doctors detect fungal infections in leukemia patients who are at high risk due to their treatment.

  Recruiting University of Zurich · Zurich, Canton of Zurich · NCT06537726

• Using stem cell exosomes to help recover from chemotherapy side effects in leukemia patients

  This study is testing if giving leukemia patients special stem cell treatments can help them recover better from the side effects of chemotherapy.

  Recruiting Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06245746

• Treatment for chronic neutropenia using mavorixafor

  This study is testing if a new drug called mavorixafor can help people with chronic neutropenia, a condition that makes them prone to infections, by boosting their white blood cell levels and lowering infection rates.

  Recruiting at 107 sites Phase 3 X4 Pharmaceuticals · Phoenix, Arizona and 113 other locations · NCT06056297

• Using Xerava to prevent infections in patients with blood cancers and low white blood cell counts

  This study is testing if the antibiotic Xerava can help prevent infections in patients with blood cancers who have low white blood cell counts during their treatment.

  Recruiting Phase 2 West Virginia University · Morgantown, West Virginia · NCT05537896

• Observational study of neutropenic patients in Cologne

  This study looks at patients who have low white blood cell counts after chemotherapy for blood cancers to see how it affects their health and what treatments work best for them.

  Recruiting University Hospital of Cologne · Cologne, North Rhine-Westphalia · NCT01821456

NIH-funded research (17)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Severe Chronic Neutropenia Registry for Patients

  A patient-facing registry that tracks severe chronic low neutrophil counts to improve understanding and care for people with this condition.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11614272

• Severe Chronic Neutropenia Registry to Improve Care

  A patient-focused registry gathers information from adults with severe chronic neutropenia to better understand infections, treatments, and outcomes over time.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11614271

• Severe Chronic Neutropenia Registry: Finding Better Ways to Prevent Infections

  A patient-focused registry at a leading hospital helps people with severe chronic neutropenia learn how the condition progresses and how treatments work over time.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11614270

• Stimulant that grows donor stem cells in the body to speed neutropenia recovery after chemotherapy and stem cell transplant

  A drug given during or right before stem cell transplant helps donor stem cells multiply quickly inside the patient to shorten neutropenia after treatment.

  NIH research Ship of Theseus, LLC · Eagleville, UNITED STATES · NIH-11424742

• Stimulant to grow stem cells in the body to speed recovery after chemotherapy and stem cell transplant

  A new drug given briefly before transplant aims to help patients recover their blood and immune system faster after chemotherapy or stem cell transplant.

  NIH research Ship of Theseus, LLC · Eagleville, UNITED STATES · NIH-11398254

• PointCheck: a home-based, non-invasive neutropenia monitor for chemotherapy patients

  A portable, non-invasive device helps cancer patients on chemotherapy monitor neutropenia from home so doctors can prevent serious infections.

  NIH research Leuko Labs, INC. · Cambridge, United States · NIH-11364218

• Understanding how DARC/ACKR1 genetic differences affect white blood cell counts in African Americans

  A study explores how a common genetic variant tied to DARC/ACKR1 affects white blood cell and neutrophil counts in African American people, to help clinicians interpret these tests more accurately.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11331261

• Drug to boost stem cell growth and shorten low-white-blood-cell time after transplant

  A brief drug treatment given to donor stem cells aims to help them grow faster inside the body so people recovering from chemotherapy or a stem cell transplant make white blood cells sooner.

  NIH research Ship of Theseus, LLC · Eagleville, UNITED STATES · NIH-11255048

• International Severe Chronic Neutropenia Registry

  A global database that collects health and treatment information from people with severe chronic neutropenia to help improve care and outcomes.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11146367

• A portable device to detect low white blood cell counts in cancer patients

  This project is developing a new portable device called PointCheck to help cancer patients on chemotherapy monitor their white blood cell counts from home and prevent serious infections.

  NIH research Leuko Labs, INC. · Boston, United States · NIH-11125802

• Understanding how a genetic variant affects white blood cell counts in certain populations

  This study is looking at how a certain gene variation affects white blood cell counts in African Americans, with the goal of helping doctors better diagnose infections and manage chemotherapy for patients with this genetic difference.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11091664

• Understanding immune responses to Aspergillus in patients with low neutrophil counts

  This study is looking at how the immune system fights off Aspergillus infections in people with neutropenia, a condition where the body has low levels of infection-fighting cells, to find ways to improve treatments for those affected by serious lung infections.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10949011

• Developing a drug to enhance stem cell growth for faster recovery after chemotherapy and bone marrow transplant

  This study is testing a new drug that helps boost the growth of stem cells in patients getting a stem cell transplant, with the goal of speeding up recovery and reducing the risk of infections after the procedure.

  NIH research Ship of Theseus, LLC · Eagleville, UNITED STATES · NIH-10918070

• A device to monitor cancer patients for low white blood cell counts at home

  This study is testing a new, easy-to-use device called PointCheck that helps cancer patients on chemotherapy check their white blood cell counts at home, so they can catch any serious drops in their levels early and stay safe from infections.

  NIH research Leuko Labs, INC. · Boston, United States · NIH-10911683

• A registry for understanding severe chronic neutropenia and its treatments

  This study is all about helping people with severe chronic neutropenia (SCN) by gathering information from patients to learn more about the condition and find better treatments, so your experiences can make a difference in future care.

  NIH research Boston Children's Hospital · Boston, United States · NIH-10897770

• Understanding a genetic cause of severe congenital neutropenia

  This study is looking at how changes in a protein called VPS45 can cause severe congenital neutropenia, a condition that makes it hard for your body to fight infections, and it's for anyone interested in understanding more about this disease and finding new ways to help.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-10767281

• Understanding how mutations in the CLPB gene affect blood cell development

  This study is looking at how changes in the CLPB gene can cause congenital neutropenia, a condition that makes it hard for your body to make white blood cells, which are important for fighting infections, and the researchers hope to find ways to help people with this condition feel better.

  NIH research Kansas State University · Manhattan, United States · NIH-10630259

Related topics

Quick answers

How many Neutropenia clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 28 countries. The most sites are in China (5 trials), United States (4 trials), Germany (2 trials), Switzerland (2 trials), Argentina (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 3: 1, Early Phase 1: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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