Examining the impact of preoperative anemia on surgical complications
Official title: Impact of Preoperative Anemia Severity and Classification on Perioperative Oxygen Supply-Demand Imbalance-Related Complications--A Prospective Observational Multi-center Cohort Study
Run by Peking Union Medical College Hospital · NCT06499974 · Data updated 2026-11-12
This study is trying to see how different types of anemia before surgery affect the risk of complications during and after moderate- to high-risk surgeries.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Peking Union Medical College Hospital Academic / other |
| Locations | 11 sites (Wuhu, Anhui and 10 other locations) |
| Status | Recruiting |
| Started | August 2, 2024 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2028 |
| Registry record updated | October 13, 2026 |
| Trial ID | NCT06499974 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older scheduled for elective moderate- to high-risk surgeries lasting over one hour.
✕Probably not a fit
Patients with severe comorbidities, hematological diseases other than anemia, or those living at high altitudes may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates how different types of preoperative anemia affect the incidence of perioperative complications in patients undergoing moderate- to high-risk surgeries. It classifies anemia into categories such as iron-deficiency anemia, anemia of chronic disease, and combined anemia, and compares these groups to a control group of patients without anemia. The study involves screening patients based on specific inclusion and exclusion criteria, measuring hemoglobin levels, and conducting lab tests to assess anemia status. All participants will undergo similar perioperative assessments and follow-ups to evaluate outcomes related to oxygen supply and demand imbalances.
Why it matters
Potential benefit: If successful, this study could improve the management of anemia in surgical patients, potentially reducing complications and enhancing recovery.
How similar studies have gone: Previous studies have indicated that managing anemia preoperatively can lead to better surgical outcomes, suggesting this approach has potential based on existing evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age 18 years or older * scheduled for elective moderate- to high-risk surgery other than intracranial and cardiac surgery * predicted surgery time longer than 1 hour and hospital stay longer than 24 hours * understand and agree to participate Exclusion Criteria: * pregnant * live at areas higher than 2,500 meters above sea level * with hematological diseases other than anemia * with severe comorbidities that might interfere outcome assessment, like uremia, dementia, and so on * can't cooperate or communicate, or reject to sign informed consent form
Where it's running
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Department of Anesthesiology, First Affiliated Hospital of Wannan Medical College
Wuhu, Anhui, China Recruiting -
Beijing Longfu Hospital (Beijing Geriatric Hospital of Integrated Traditional Chinese and Western Medicine)
Beijing, Beijing Municipality, China Recruiting -
Anesthesiology Department, Beijing NO.6 Hospital
Beijing, Beijing Municipality, China Recruiting -
BeiJing Hepingli Hospital
Beijing, Beijing Municipality, China Recruiting -
Beijing Puren Hospital
Beijing, Beijing Municipality, China Recruiting -
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China Recruiting
Show 5 more locations
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Science and Education Department, Zhangzhou Municipal Hospital of Fujian Province
Zhangzhou, Fujian, China Recruiting -
Department of Anesthesiology, Affiliated Hospital of Zunyi Medical University
Zunyi, Guizhou, China Recruiting -
Department of Anesthesiology, Chifeng Municipal Hospital
Chifeng, Inner Mongolia, China Recruiting -
Department of Anesthesiology, The Affiliated Hospital of Inner Mongolia Medical University
Hohhot, Inner Mongolia, China Recruiting -
Inner Mongolia People's Hospital
Hohhot, Inner Mongolia, China Recruiting
Study contacts
- Study coordinator: Lu Che
- Email: tracymaobao@126.com
- Phone: 15901045120
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.