Clinical trial Recruiting at 11 sites Observational Ages 18 and up

Examining the impact of preoperative anemia on surgical complications

Official title: Impact of Preoperative Anemia Severity and Classification on Perioperative Oxygen Supply-Demand Imbalance-Related Complications--A Prospective Observational Multi-center Cohort Study

Run by Peking Union Medical College Hospital · NCT06499974 · Data updated 2026-11-12

This study is trying to see how different types of anemia before surgery affect the risk of complications during and after moderate- to high-risk surgeries.

More Anemia trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorPeking Union Medical College Hospital
Academic / other
Locations11 sites (Wuhu, Anhui and 10 other locations)
StatusRecruiting
StartedAugust 2, 2024
Main results expectedDecember 31, 2027
Study endsDecember 31, 2028
Registry record updatedOctober 13, 2026
Trial IDNCT06499974 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older scheduled for elective moderate- to high-risk surgeries lasting over one hour.

Probably not a fit

Patients with severe comorbidities, hematological diseases other than anemia, or those living at high altitudes may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how different types of preoperative anemia affect the incidence of perioperative complications in patients undergoing moderate- to high-risk surgeries. It classifies anemia into categories such as iron-deficiency anemia, anemia of chronic disease, and combined anemia, and compares these groups to a control group of patients without anemia. The study involves screening patients based on specific inclusion and exclusion criteria, measuring hemoglobin levels, and conducting lab tests to assess anemia status. All participants will undergo similar perioperative assessments and follow-ups to evaluate outcomes related to oxygen supply and demand imbalances.

Why it matters

Potential benefit: If successful, this study could improve the management of anemia in surgical patients, potentially reducing complications and enhancing recovery.

How similar studies have gone: Previous studies have indicated that managing anemia preoperatively can lead to better surgical outcomes, suggesting this approach has potential based on existing evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age 18 years or older
* scheduled for elective moderate- to high-risk surgery other than intracranial and cardiac surgery
* predicted surgery time longer than 1 hour and hospital stay longer than 24 hours
* understand and agree to participate

Exclusion Criteria:

* pregnant
* live at areas higher than 2,500 meters above sea level
* with hematological diseases other than anemia
* with severe comorbidities that might interfere outcome assessment, like uremia, dementia, and so on
* can't cooperate or communicate, or reject to sign informed consent form

Where it's running

  • Department of Anesthesiology, First Affiliated Hospital of Wannan Medical College
    Wuhu, Anhui, China
    Recruiting
  • Beijing Longfu Hospital (Beijing Geriatric Hospital of Integrated Traditional Chinese and Western Medicine)
    Beijing, Beijing Municipality, China
    Recruiting
  • Anesthesiology Department, Beijing NO.6 Hospital
    Beijing, Beijing Municipality, China
    Recruiting
  • BeiJing Hepingli Hospital
    Beijing, Beijing Municipality, China
    Recruiting
  • Beijing Puren Hospital
    Beijing, Beijing Municipality, China
    Recruiting
  • Peking Union Medical College Hospital
    Beijing, Beijing Municipality, China
    Recruiting
Show 5 more locations
  • Science and Education Department, Zhangzhou Municipal Hospital of Fujian Province
    Zhangzhou, Fujian, China
    Recruiting
  • Department of Anesthesiology, Affiliated Hospital of Zunyi Medical University
    Zunyi, Guizhou, China
    Recruiting
  • Department of Anesthesiology, Chifeng Municipal Hospital
    Chifeng, Inner Mongolia, China
    Recruiting
  • Department of Anesthesiology, The Affiliated Hospital of Inner Mongolia Medical University
    Hohhot, Inner Mongolia, China
    Recruiting
  • Inner Mongolia People's Hospital
    Hohhot, Inner Mongolia, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.