Sponsor or institution

Clinical trials and research at Wright State University

• 10Clinical trials
• 35NIH research projects
• 1Country

Newest trials

All recruiting trials (10)

• Intranasal sphenopalatine ganglion block for headache after a ruptured brain aneurysm

  This will test whether spraying a numbing medicine into the back of the nose can reduce severe headache in adults recovering from a ruptured brain aneurysm.

  Recruiting Phase 4 Wright State University · Dayton, Ohio · NCT07116408

• Mechanisms for Laser-Induced Rejuvenation in Skin Cancer Risk Reduction

  This study tests whether cells called fibroblasts that appear after Fractionated Laser Resurfacing can be traced to their origin in people planning abdominoplasty.

  Recruiting Wright State University · Fairborn, Ohio · NCT06489301

• Using laser treatment to prevent skin cancer in older adults with precancerous lesions

  This study tests if a special laser treatment can help older adults with precancerous skin spots avoid developing skin cancer.

  Recruiting Wright State University · Fairborn, Ohio · NCT06428721

• Using topical medications to reduce redness from sunlight in rosacea patients

  This study is testing whether two topical medications can help reduce redness from sunlight in people with rosacea.

  Recruiting Phase 2 Wright State University · Fairborn, Ohio · NCT06312813

• Using Imipramine to Reduce Pain from Photodynamic Therapy for Skin Lesions

  This study is testing if using Imipramine with photodynamic therapy can help reduce pain for people getting treatment for actinic keratosis.

  Recruiting Phase 1 Wright State University · Fairborn, Ohio · NCT05688904

• Testing a cream to reduce skin reactions to sunlight in sensitive individuals

  This study tests if a cream can help people who are sensitive to sunlight by reducing skin reactions after they are exposed to UV light.

  Recruiting Phase 1 Wright State University · Fairborn, Ohio · NCT04520217

• Examining skin responses to UV light in day and night shift workers

  This study tests how the skin of night shift workers reacts to UV light compared to day shift workers to see if their different schedules affect skin health and cancer risk.

  Recruiting Wright State University · Fairborn, Ohio · NCT04122456

• Combining triamcinolone and vitamin D for treating psoriasis

  This study is testing if using a cream with triamcinolone and taking vitamin D3 can help people with mild to moderate psoriasis feel better.

  Recruiting Early Phase 1 Wright State University · Fairborn, Ohio · NCT04036188

• Effects of UVB on Young and Older Skin

  This study is testing how young and older skin react to UVB rays and whether a treatment can help older skin act more like younger skin.

  Recruiting Early Phase 1 Wright State University · Fairborn, Ohio · NCT03932162

• Using laser treatment to protect older skin from skin cancer

  This study tests if a special laser treatment can help older adults with actinic keratosis reduce their chances of developing skin cancer in the future.

  Recruiting Wright State University · Dayton, Ohio · NCT03906253

NIH-funded research (35)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Excitability dysfunction in ALS and FTD linked to TDP-43

  A patient-focused research opportunity to understand how nerve cell electrical activity goes wrong in ALS and related dementia linked to TDP-43.

  NIH research Wright State University · Dayton, United States · NIH-11601035

• Glycosylation changes that boost heart signals and lead to heart failure

  A study to understand how changes in sugar attachments on heart cell receptors may fuel heart failure, with potential to guide new treatments.

  NIH research Wright State University · Dayton, United States · NIH-11445090

• Regulation of TRPM7 in low and high magnesium conditions

  This grant studies how the TRPM7 ion channel and enzyme influence immune cell function when magnesium levels change, which could affect immune responses in people.

  NIH research Wright State University · Dayton, United States · NIH-11444919

• Lipin1 and Micro-Dystrophin Gene Therapies for DMD: A New Dual Approach

  A study to explore whether boosting Lipin1 together with micro-dystrophin gene therapy could improve muscle and heart health in Duchenne muscular dystrophy patients.

  NIH research Wright State University · Dayton, United States · NIH-11441231

• Neuromuscular Junction Problems in Hyperkalemic Paralysis

  A clinician-scientist is pursuing five years of advanced training and research to better understand and care for people with neuromuscular diseases related to hyperkalemic paralysis.

  NIH research Wright State University · Dayton, United States · NIH-11393593

• Understanding why nerve cells in ALS and FTD misfire and how to help them

  Aims to understand why motor neurons become over- or under-responsive in ALS and related brain disorders using a mouse model that mimics human disease.

  NIH research Wright State University · Dayton, United States · NIH-11386359

• TDP-43 linked nerve cell electrical problems in ALS and frontotemporal dementia

  This project looks at how TDP-43-related changes in nerve cell electrical activity may lead to ALS and frontotemporal dementia, using mouse models that mirror most patients' disease.

  NIH research Wright State University · Dayton, United States · NIH-11377867

• Nerve cell excitability changes in ALS and frontotemporal dementia linked to TDP‑43

  Researchers will look at how TDP‑43 related changes alter motor neuron electrical activity in models of ALS and frontotemporal dementia to better understand causes of nerve cell loss.

  NIH research Wright State University · Dayton, United States · NIH-11377866

• Platelet-activating Factor and Skin Burn Inflammation

  This project looks at how a fat molecule called PAF drives inflammation after severe burns and whether blocking it could help people recover.

  NIH research Wright State University · Dayton, United States · NIH-11363235

• New treatments for muscle ion channel disorders

  Researchers are testing whether targeting a specific sodium current can reduce muscle stiffness and prevent weakness in people with myotonia congenita and hyperkalemic periodic paralysis.

  NIH research Wright State University · Dayton, United States · NIH-11321140

• How motor nerve cells' activity is controlled in ALS

  This research looks at why motor nerve cells in people with ALS swing between being too active and too quiet, and how those swings may lead to cell damage.

  NIH research Wright State University · Dayton, United States · NIH-11261087

• How cells spot and protect DNA when copying goes wrong

  Using yeast as a model, researchers aim to learn how cells detect and protect DNA during copying errors to help improve cancer treatments.

  NIH research Wright State University · Dayton, United States · NIH-11261077

• How two proteins (ΔNp63α and TIP60) help squamous cell cancers resist chemotherapy

  This work explores whether blocking the proteins ΔNp63α and TIP60 can help people with squamous cell carcinoma respond better to cisplatin chemotherapy.

  NIH research Wright State University · Dayton, United States · NIH-11225130

• Skin wounding and sun-caused skin cancer

  This research looks at how skin injuries and aging change the way sun exposure leads to common skin cancers in older adults.

  NIH research Wright State University · Dayton, United States · NIH-11173795

• Nerve-cell excitability in TDP-43 linked ALS and frontotemporal dementia

  Researchers are looking at how TDP-43–related changes in nerve‑cell activity might harm motor neurons in ALS and frontotemporal dementia.

  NIH research Wright State University · Dayton, United States · NIH-11164543

• Investigating how zinc supplementation can protect kidneys in chronic kidney disease.

  This study is looking at how taking zinc might help people with chronic kidney disease and high blood pressure by using mice to see how zinc affects their kidneys and blood pressure, with hopes of finding new ways to help manage these conditions better.

  NIH research Wright State University · Dayton, United States · NIH-11140310

• Protecting Skin from Chemical Threats

  This grant explores how specific chemicals harm the skin and body, aiming to discover new ways to protect people from these effects.

  NIH research Wright State University · Dayton, United States · NIH-11131215

• Improving Muscle Health in Duchenne Muscular Dystrophy

  This project explores how a protein called Lipin1 might help strengthen muscles and protect them from damage in Duchenne muscular dystrophy.

  NIH research Wright State University · Dayton, United States · NIH-11092895

• Manipulating genes in the placenta during pregnancy

  This study is exploring a new way to change genes in the placenta while it's still in the womb, which could help us learn more about how the placenta works and improve treatments for issues related to it, all without needing surgery.

  NIH research Wright State University · Dayton, United States · NIH-11055396

• Understanding how excitability issues contribute to ALS and FTD.

  This study is looking at how nerve cells behave in people with ALS and frontotemporal dementia, using special mouse models to figure out if changes in these cells are helping or hurting, which could lead to better treatments for patients like you.

  NIH research Wright State University · Dayton, United States · NIH-11054719

• New treatments for muscle diseases caused by ion channel problems

  This study is looking at two muscle conditions, myotonia congenita and hyperkalemic periodic paralysis, to see how certain channels in our muscles affect stiffness and weakness, with the goal of finding better treatments to help people with these issues feel better.

  NIH research Wright State University · Dayton, United States · NIH-11047918

• How UVB radiation affects skin signaling through tiny particles

  This study is looking at how UVB rays from the sun affect your skin and send signals throughout your body, focusing on tiny particles released by skin cells that might carry important substances influencing your health.

  NIH research Wright State University · Dayton, United States · NIH-11017002

• Understanding how cells respond to DNA replication issues in fission yeast

  This study is looking at how certain cells, like those in fission yeast, respond to problems during DNA copying to keep our genetic material safe, and it aims to help us understand how these processes work in human cells too.

  NIH research Wright State University · Dayton, United States · NIH-11015026

• Understanding how certain proteins affect cancer treatment resistance

  This study is looking at how certain proteins might affect the growth of squamous cell carcinoma and why some patients don’t respond well to the chemotherapy drug cisplatin, with the hope of finding better treatment options for those who struggle with current therapies.

  NIH research Wright State University · Dayton, United States · NIH-10996158

• How damaged DNA travels in autoimmune skin disorders

  This study is looking at how damaged DNA from skin cells, caused by sun exposure, might move through the body and make autoimmune conditions like lupus worse, by examining tiny particles in urine to see how they relate to inflammation and disease severity.

  NIH research Wright State University · Dayton, United States · NIH-10985817

• How environmental pollutants affect skin cancer risk from UV exposure

  This study is looking at how sunlight and certain pollutants in the environment can work together to increase the risk of skin cancer, helping us understand how these factors affect your skin's immune system and overall health.

  NIH research Wright State University · Dayton, United States · NIH-10940266

• Understanding and treating muscle paralysis caused by genetic mutations

  This study is looking at Hyperkalemic Periodic Paralysis, a genetic condition that causes muscle weakness and paralysis, using mice to better understand how it works and to find better treatments for people living with this condition.

  NIH research Wright State University · Dayton, United States · NIH-10906368

• Understanding how certain medications cause kidney damage

  This study is looking at how certain medications used to prevent organ rejection in transplant patients can sometimes harm the kidneys over time, and it aims to understand the reasons behind this damage so that better treatments can be developed to keep your kidneys healthy.

  NIH research Wright State University · Dayton, United States · NIH-10906319

• Investigating how stress in brain cells affects cognitive function in people with type 2 diabetes.

  This study is looking at how stress in brain cells might affect thinking and memory in people with type 2 diabetes, and it hopes to find ways to fix these changes to help improve brain function.

  NIH research Wright State University · Dayton, United States · NIH-10897829

• Investigating how oxidized lipids and microvesicles affect skin responses to chemical threats

  This study is looking into how certain harmful chemicals from warfare can affect your skin and body, with the goal of finding better treatments for anyone who has been exposed to them.

  NIH research Wright State University · Dayton, United States · NIH-10885063

• Understanding how nerve cell dysfunction contributes to ALS and frontotemporal dementia

  This study is looking into how nerve cells work differently in people with ALS and frontotemporal dementia, focusing on a protein called TDP43, to help find better treatments for those affected by these conditions.

  NIH research Wright State University · Dayton, United States · NIH-10835959

• Investigating how FBXL16 contributes to breast cancer treatment resistance and spread

  This study is looking at how a protein called FBXL16 influences estrogen receptor-positive breast cancer, especially why some patients don’t respond to hormone therapy and how the cancer might spread, with the goal of finding better treatment options for those facing advanced breast cancer.

  NIH research Wright State University · Dayton, United States · NIH-10794658

• How environmental pollutants affect skin cancer responses to UV radiation

  This study is looking at how sunlight and certain pollutants in the environment can affect your skin health and increase the risk of skin cancer, helping us understand how these factors work together in your body.

  NIH research Wright State University · Dayton, United States · NIH-10688121

• How a glucose byproduct affects nerve function in Alzheimer's disease

  This study is looking at how a substance called methylglyoxal, which comes from how our bodies process sugar, can harm important parts of nerve cells that help send signals in the brain, especially in people with Alzheimer's disease and type 2 diabetes, with the hope of finding new ways to improve brain function and me

  NIH research Wright State University · Dayton, United States · NIH-10443534

• Investigating how RNA-binding proteins can reduce toxicity caused by FUS in yeast.

  This study is looking at how certain proteins in our cells can help protect against the harmful effects of a protein linked to ALS, and it aims to find new ways to treat people with this condition.

  NIH research Wright State University · Dayton, United States · NIH-10202952

Quick answers

How many clinical trials run by Wright State University are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 2, Phase 1: 2, Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →