Neuromuscular Junction Problems in Hyperkalemic Paralysis
Official title: Neuromuscular Junction Dysfunction in Hyperkalemic Periodic Paralysis
Funded at Wright State University · NIH-11393593 · Data updated 2026-11-12
A clinician-scientist is pursuing five years of advanced training and research to better understand and care for people with neuromuscular diseases related to hyperkalemic paralysis.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wright State University NIH-funded |
| Lab location | 1 site (Dayton, United States) |
| Project start | August 14, 2025 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $165,456 |
| NIH project number | 5K08AR085924-02 |
| Project ID | NIH-11393593 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals with neuromuscular disorders, especially those affecting motor unit function and conditions like hyperkalemic periodic paralysis.
✕Less likely to help
Patients without neuromuscular conditions may not directly benefit from this specific training-focused grant.
What this research studies
This grant supports a five-year program where the investigator will gain hands-on training in intracellular electrophysiology and translational neuromuscular physiology to improve patient care. The project combines clinical neurology with laboratory work to study how motor units and muscle signaling function in people with neuromuscular conditions. Mentorship from an expert team will guide hypothesis-driven experiments that can be rapidly translated into clinical practice. The aim is to build a sustainable research career capable of advancing therapies and diagnostic approaches for patients with neuromuscular diseases.
Why it matters
Potential benefit: If successful, patients with neuromuscular diseases may receive faster-moving advances in diagnosis and treatment that stem from deeper physiological understanding.
How similar studies have gone: Prior work in translational neuromuscular physiology has shown promise in linking cellular mechanisms to clinical care, supporting potential for meaningful impact.
Where this research is happening
-
Wright State University
Dayton, United States Active
Researchers
- Principal investigator: Deardorff, Adam S — Wright State University
- Study coordinator: Deardorff, Adam S
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.