Investigating how zinc supplementation can protect kidneys in chronic kidney disease.
Official title: Mechanisms of the Renoprotective Properties of Zinc Supplementation in Mouse Models of Chronic Kidney Disease
Funded at Wright State University · NIH-11140310 · Data updated 2026-11-12
This study is looking at how taking zinc might help people with chronic kidney disease and high blood pressure by using mice to see how zinc affects their kidneys and blood pressure, with hopes of finding new ways to help manage these conditions better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wright State University NIH-funded |
| Lab location | 1 site (Dayton, United States) |
| Project start | August 31, 2022 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $485,718 |
| NIH project number | 5R01DK133698-04 |
| Project ID | NIH-11140310 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with early-stage chronic kidney disease who also experience hypertension.
✕Less likely to help
Patients with advanced chronic kidney disease or those who do not have hypertension may not benefit from this research.
What this research studies
This research explores the potential benefits of zinc supplementation for patients with chronic kidney disease (CKD), particularly those experiencing hypertension. The study uses mouse models to understand how zinc affects kidney function and blood pressure regulation. By examining the relationship between zinc levels and kidney health, the research aims to identify new strategies to manage hypertension and prevent further kidney damage. The findings could lead to innovative treatments that improve patient outcomes in CKD.
Why it matters
Potential benefit: If successful, this research could provide a novel approach to managing hypertension and protecting kidney function in patients with chronic kidney disease.
How similar studies have gone: While the specific approach of zinc supplementation in CKD is relatively novel, there is existing evidence suggesting that zinc plays a crucial role in kidney health and blood pressure regulation.
Where this research is happening
-
Wright State University
Dayton, United States Active
Researchers
- Principal investigator: Williams, Clintoria Richards — Wright State University
- Study coordinator: Williams, Clintoria Richards
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.