Investigating how oxidized lipids and microvesicles affect skin responses to chemical threats
Official title: Oxidized lipids and microvesicle particles as effectors for chemical threats to skin
Funded at Wright State University · NIH-10885063 · Data updated 2026-11-12
This study is looking into how certain harmful chemicals from warfare can affect your skin and body, with the goal of finding better treatments for anyone who has been exposed to them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wright State University NIH-funded |
| Lab location | 1 site (Dayton, United States) |
| Project start | July 10, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $262,500 |
| NIH project number | 5R34AR082554-02 |
| Project ID | NIH-10885063 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have been exposed to chemical warfare agents or are at risk of such exposure.
✕Less likely to help
Patients who have not been exposed to chemical agents or who do not have related health conditions may not benefit from this research.
What this research studies
This research focuses on understanding the harmful effects of chemical warfare agents, such as arsenicals and nitrogen mustards, on the skin and body. It aims to uncover the molecular mechanisms behind these effects, particularly how exposure to these agents can lead to inflammation and organ dysfunction. The study will explore the role of oxidized lipids and microvesicle particles in these processes, potentially leading to the development of new antidotes. By examining how these substances interact with the body, the research seeks to provide insights that could improve treatment options for affected individuals.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective antidotes for chemical exposure, improving patient outcomes and survival rates.
How similar studies have gone: While the approach of investigating oxidized lipids and microvesicles is innovative, similar studies have shown promise in understanding the effects of chemical agents on the body.
Where this research is happening
-
Wright State University
Dayton, United States Active
Researchers
- Principal investigator: Travers, Jeffrey B. — Wright State University
- Study coordinator: Travers, Jeffrey B.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.