Sponsor or institution

Clinical trials and research at National Jewish Health

• 7Clinical trials
• 83NIH research projects
• 1Country

Newest trials

All recruiting trials (7)

• Evaluating Omalizumab's Effect on Skin in Food Allergy Patients

  This study is testing if the medication omalizumab can improve skin problems in people with food allergies and help reduce their allergic reactions.

  Recruiting Phase 4 National Jewish Health · Denver, Colorado · NCT06618963

• Helping patients reduce reliance on sleep medications in primary care

  This study is testing a new way to help people with insomnia safely cut back on sleep medications by using a combination of online therapy and a plan to reduce their medication, compared to regular care.

  Recruiting Phase 4 National Jewish Health · Denver, Colorado · NCT06435520

• Understanding how white blood cells affect lung inflammation in patients on ventilators

  This study is trying to see how a type of white blood cell affects lung inflammation in adults on ventilators, especially those with Acute Respiratory Distress Syndrome, to help improve treatments for lung injuries.

  Recruiting National Jewish Health · Denver, Colorado · NCT05767671

• Investigating how macrophages respond to lung inflammation after endotoxin exposure

  This study is testing how certain immune cells in the lungs react to inflammation caused by endotoxins to help improve our understanding of lung repair in conditions like Acute Respiratory Distress Syndrome (ARDS).

  Recruiting National Jewish Health · Denver, Colorado · NCT03859050

• Investigating the link between laryngopharyngeal reflux and idiopathic pulmonary fibrosis

  This study is testing if a new way to measure throat reflux can help doctors understand how it affects people with idiopathic pulmonary fibrosis.

  Recruiting National Jewish Health · Denver, Colorado · NCT03418350

• Research database and biorepository for lung disease in veterans and contractors

  This study is creating a database and collection of blood samples from veterans and contractors who served in Iraq and Afghanistan to better understand lung diseases they may have developed from their service.

  Recruiting National Jewish Health · Denver, Colorado · NCT03035097

• Reslizumab treatment for eosinophilic granulomatosis with polyangiitis (EGPA)

  This study will try reslizumab, an anti–IL-5 antibody, in adults with EGPA to see if it helps control symptoms and reduce the need for oral steroids.

  Recruiting Phase 2 National Jewish Health · Denver, Colorado · NCT02947945

NIH-funded research (newest 40 of 83)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Predictive models for BeS and CBD in exposed workers

  Aimed at people exposed to beryllium, this project will build models to identify who is at risk for beryllium sensitization and Chronic Beryllium Disease using lung samples and data.

  NIH research National Jewish Health · Denver, United States · NIH-11592226

• Understanding how early skin biology affects the development of allergies in children

  A study with infants and young children aims to understand why some kids with eczema (atopic dermatitis) go on to develop food allergies and asthma, by looking at skin biology and immune patterns still early in life.

  NIH research National Jewish Health · Denver, United States · NIH-11580964

• Rare airway cells and how they affect lung infections after a viral illness

  This NIH grant looks at a rare airway cell type called M cells to see how they influence secondary bacterial infections after a viral lung illness.

  NIH research National Jewish Health · Denver, United States · NIH-11550180

• Obinutuzumab for CTD-Related Interstitial Lung Disease in adults

  This project tests whether the anti-B cell therapy obinutuzumab can help adults with connective tissue disease–related ILD who are on mycophenolate therapy.

  NIH research National Jewish Health · Denver, United States · NIH-11451497

• Effects of Temperature Fluctuation on the Skin Barrier (K08)

  A clinician-scientist is being mentored over 5 years to understand how changes in temperature affect the skin barrier and the development of allergies in children.

  NIH research National Jewish Health · Denver, United States · NIH-11437439

• Precision tapering of dupilumab in asthma for safer, cost-saving interval extension

  We’re testing if adults with well-controlled asthma on dupilumab can safely extend the time between injections to reduce costs and burden.

  NIH research National Jewish Health · Denver, United States · NIH-11436814

• Right ventricle health in pulmonary hypertension: sex differences and new treatment ideas

  A study in rats explores how female hormones and a specific immune pathway affect the right heart’s ability to cope with high blood pressure in the lungs, and tests potential ways to improve heart function.

  NIH research National Jewish Health · Denver, United States · NIH-11401155

• SFTA2 and ADGRF5: a pathway that could protect the lungs from severe injury

  This grant studies how a lung cell signaling pathway involving SFTA2 and ADGRF5 could help keep lung surfactant balance and reduce damage in serious lung illnesses.

  NIH research National Jewish Health · Denver, United States · NIH-11399181

• Molecular markers of progressive pulmonary sarcoidosis

  This grant looks at proteins and genes in people with sarcoidosis to find early signs that the disease will worsen from the lungs.

  NIH research National Jewish Health · Denver, United States · NIH-11396447

• RNA edits that affect lung blood vessel cells in pulmonary hypertension

  This grant explores how RNA editing in lung blood vessel cells may influence pulmonary hypertension and its progression, with the goal of guiding future therapies for patients.

  NIH research National Jewish Health · Denver, United States · NIH-11393161

• Termination of lung inflammation by MyD88 alternative splicing

  A study in mice is examining how a gene splice variant called MyD88-S might control lung inflammation related to ARDS, with potential to identify new ways to prevent chronic lung inflammation.

  NIH research National Jewish Health · Denver, United States · NIH-11388744

• How loss of lung progenitor cells speeds up lung aging

  This project looks at whether losing certain lung progenitor cells and their immune signals causes faster lung aging and emphysema in adults, including people with COPD.

  NIH research National Jewish Health · Denver, United States · NIH-11381699

• How certain lung macrophage cells help repair the lung after inflammation

  This project studies specific immune cells in the lungs to understand how they clear dead cells and help repair tissue after lung inflammation, with a focus on adults who develop acute respiratory distress.

  NIH research National Jewish Health · Denver, United States · NIH-11371172

• SUNBEAM Birth Cohort: How early skin issues shape future allergies in kids

  A long-term study follows infants to see how early skin problems may set the stage for future allergies like eczema, food allergies, and asthma.

  NIH research National Jewish Health · Denver, United States · NIH-11367439

• Fibroblasts and dying cells: how they help lung repair form collagen

  A research study looks at how lung fibroblasts interact with dead cells to boost collagen production during healing after lung injury.

  NIH research National Jewish Health · Denver, United States · NIH-11365139

• Role of FABP5 in COPD Flare-Ups

  Aims to understand how a protein called FABP5 helps lung immune cells control inflammation during COPD flare-ups and whether this could lead to new treatments.

  NIH research National Jewish Health · Denver, United States · NIH-11364163

• SUNBEAM: following babies to understand early childhood allergies

  This project follows infants and young children to find early-life signs and causes of allergies and asthma.

  NIH research National Jewish Health · Denver, United States · NIH-11358688

• Glucose and amino acid transport as targets to boost CF immune responses

  This grant explores how glucose and amino acid transport in immune cells may be linked to better outcomes for adults with cystic fibrosis who still have lung infections despite standard therapies.

  NIH research National Jewish Health · Denver, United States · NIH-11357262

• Environmental triggers shaping early immune cells and asthma risk in children

  A study in a mouse model explores how a mother’s exposure to air pollutants like diesel exhaust may program the child’s immune system to be more prone to asthma.

  NIH research National Jewish Health · Denver, United States · NIH-11354172

• Allergic disease memory and immune regulation in humans and mice

  This project studies how allergens affect a key immune cell (ILC2) to drive asthma and allergy by examining epigenetic changes and memory formation in both people and mice.

  NIH research National Jewish Health · Denver, United States · NIH-11354171

• Data stewardship for allergic disease research and data sharing

  A data-focused grant to help study asthma and allergic diseases by managing, processing, and analyzing data from two research projects and two cores.

  NIH research National Jewish Health · Denver, United States · NIH-11354170

• Understanding allergic diseases through coordinated research and data stewardship

  A nationwide research center is coordinating two projects and two cores to study allergic diseases and asthma, with strong leadership and collaborative oversight to advance patient care.

  NIH research National Jewish Health · Denver, United States · NIH-11354169

• How our genes and immune cells remember allergies in kids and adults

  A national study will look at how genes and immune cells remember allergies, from children to adults, to understand why allergic reactions happen and persist.

  NIH research National Jewish Health · Denver, United States · NIH-11354168

• How small protein tags (ISG15 and ATG12) help cells handle stress

  This project looks at how two small protein tags, ISG15 and ATG12, change cell behavior during stress in ways that matter for people with cancer, autoimmune, or neurodegenerative diseases.

  NIH research National Jewish Health · Denver, United States · NIH-11331432

• How GM‑CSF and lung macrophages affect Mycobacterium abscessus lung infections

  This research looks at whether the immune signal GM‑CSF and different lung immune cells help protect people with chronic airway diseases from Mycobacterium abscessus lung infections.

  NIH research National Jewish Health · Denver, United States · NIH-11331242

• Turning on MMP-9 to help clear lung scarring

  This work tries to activate an enzyme called MMP-9 so people with lung scarring, like idiopathic pulmonary fibrosis, can break down and clear stubborn scar tissue.

  NIH research National Jewish Health · Denver, United States · NIH-11321572

• Coordinating national research on atopic dermatitis (eczema)

  A national effort that brings researchers together to better understand different types of eczema and speed development of more targeted treatments for people with atopic dermatitis.

  NIH research National Jewish Health · Denver, United States · NIH-11314555

• Center to understand and treat eczema (atopic dermatitis)

  This project looks at biological differences in people with different types of atopic dermatitis, including those prone to eczema herpeticum and those with food allergy, to help improve care for children and adults.

  NIH research National Jewish Health · Denver, United States · NIH-11310152

• New mouse and human lung models to study how T cells drive scleroderma-related lung fibrosis

  Aims to understand how specific T cell types contribute to lung scarring in scleroderma by using advanced mouse and human lung models.

  NIH research National Jewish Health · Denver, United States · NIH-11305094

• Stopping harmful inflammation from bacterial infections by targeting RIPK2

  Researchers are developing drugs that block a protein called RIPK2 to reduce damaging inflammation in people with certain bacterial infections or inflammatory conditions.

  NIH research National Jewish Health · Denver, United States · NIH-11261104

• Loss of lung blood-vessel stem cells that may speed lung aging and raise emphysema risk

  Researchers will look at how losing a type of lung blood-vessel progenitor cell may make lungs age faster and increase emphysema risk in adults.

  NIH research National Jewish Health · Denver, United States · NIH-11257257

• How mast cells develop and trigger allergic reactions

  Researchers are exploring how the MITF gene controls mast cell development and activity to better understand allergic diseases and drug-triggered mast cell reactions.

  NIH research National Jewish Health · Denver, United States · NIH-11239125

• What causes lung granulomas in chronic beryllium disease

  Researchers are using genetic and molecular tests to find what triggers the harmful lung inflammation after beryllium exposure in people with or at risk for chronic beryllium disease.

  NIH research National Jewish Health · Denver, United States · NIH-11238418

• Understanding the genetic factors and risks of COPD in smokers

  This study is looking at how genes and the environment affect chronic obstructive pulmonary disease (COPD) in people who smoke or have smoked, and it will follow participants over 15 years to see how COVID-19 might change their condition, helping us find ways to better support those at higher risk.

  NIH research National Jewish Health · Denver, United States · NIH-11219825

• Understanding how early skin problems lead to allergies in children

  This project looks at how skin issues in babies might lead to other allergies like food allergies and asthma as they grow.

  NIH research National Jewish Health · Denver, United States · NIH-11187004

• Molecular clues behind progressive lung sarcoidosis

  This project looks at proteins and genes in blood and lab granuloma models to find early signs that someone with sarcoidosis will develop worsening lung disease.

  NIH research National Jewish Health · Denver, United States · NIH-11173880

• How extracellular DNA triggers neutrophil-driven severe asthma

  Researchers are looking at whether DNA released in the airways and related immune signals cause severe neutrophilic asthma in people with asthma that is not helped by standard treatments.

  NIH research National Jewish Health · Denver, United States · NIH-11158973

• Understanding FABP5 in COPD Flares

  This research explores how a protein called FABP5 influences lung inflammation in people with chronic obstructive pulmonary disease, or COPD.

  NIH research National Jewish Health · Denver, United States · NIH-11145913

• Understanding and improving treatment for COPD through data analysis

  This study is looking at how chronic obstructive pulmonary disease (COPD) affects different people in unique ways, using advanced technology to find clues that could help doctors predict how the disease will progress and create personalized treatment plans just for you.

  NIH research National Jewish Health · Denver, United States · NIH-11144230

• Investigating how RNA editing affects blood vessel cells in pulmonary hypertension

  This study is looking at how a special enzyme called ADAR1 affects the health of cells in the lungs that help keep blood flowing properly, with the goal of finding new ways to improve treatments for people with pulmonary hypertension.

  NIH research National Jewish Health · Denver, United States · NIH-11139790

Quick answers

How many clinical trials run by National Jewish Health are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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