SUNBEAM Birth Cohort: How early skin issues shape future allergies in kids
Official title: SUNBEAM Birth Cohort: Deciphering the role of early life skin dysfunction in development of the allergic march
Funded at National Jewish Health · NIH-11367439 · Data updated 2026-11-12
A long-term study follows infants to see how early skin problems may set the stage for future allergies like eczema, food allergies, and asthma.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | National Jewish Health NIH-funded |
| Lab location | 1 site (Denver, United States) |
| Project start | September 6, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $1,310,726 |
| NIH project number | 5U01AI173502-03 |
| Project ID | NIH-11367439 on NIH RePORTER |
Who could benefit from this research
✓Could help
Infants and young children, including those with early skin conditions such as atopic dermatitis, and their families, who can participate over several years.
✕Less likely to help
Children who do not have skin-related allergies or who are not enrolled in the study may not directly benefit.
What this research studies
This project enrolls infants and tracks skin health, immune signals, and the appearance of allergic diseases over several years to understand why some children develop a broader allergic march while others do not. Researchers will collect skin and possibly blood samples, plus medical histories, to identify skin-related endotypes that precede new allergies. The study aims to map how early skin biology might influence later allergy outcomes so future prevention strategies can be developed. Children with a history of atopic dermatitis and related factors may be especially informative for this work.
Why it matters
Potential benefit: If successful, the findings could lead to earlier identification of children at risk for multiple allergies and inform new strategies to prevent or lessen allergic diseases.
How similar studies have gone: Previous work shows a link between early skin inflammation and later allergies, but the exact skin endotypes predicting progression are still being explored.
Where this research is happening
-
National Jewish Health
Denver, United States Active
Researchers
- Principal investigator: Seibold, Max a — National Jewish Health
- Study coordinator: Seibold, Max a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.