Understanding the genetic factors and risks of COPD in smokers
Official title: GENETIC EPIDEMIOLOGY OF COPD (COPD GENE) 2024 - 2025 TASK ORDER FOR TASK AREA A: COLLECTION OF COPDGENE STUDY DATA AND BIOSPECIMENS AND OVERSIGHT OF THE COPDGENE STUDY.
Funded at National Jewish Health · NIH-11219825 · Data updated 2026-11-12
This study is looking at how genes and the environment affect chronic obstructive pulmonary disease (COPD) in people who smoke or have smoked, and it will follow participants over 15 years to see how COVID-19 might change their condition, helping us find ways to better support those at higher risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | National Jewish Health NIH-funded |
| Lab location | 1 site (Denver, United States) |
| Project start | August 10, 2024 |
| Project end | August 9, 2025 |
| Funding year | 2024 |
| Award (this year) | $9,298,220 |
| NIH project number | 75N92023D00011-0-759202400001-1 |
| Project ID | NIH-11219825 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are current and former smokers, particularly those with or at risk for COPD.
✕Less likely to help
Patients who do not smoke or have never smoked may not receive benefit from this research.
What this research studies
This research investigates the genetic and environmental factors contributing to chronic obstructive pulmonary disease (COPD) among current and former smokers. It involves a multi-site longitudinal study where participants will undergo in-person clinical visits to collect data and biospecimens over a 15-year period. The study aims to assess the impact of COVID-19 on COPD progression and identify high-risk subgroups for targeted interventions. Participants will provide clinical, physiological, imaging, and molecular data to enhance understanding of COPD and related diseases.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for COPD and related smoking-related diseases.
How similar studies have gone: Previous studies in genetic epidemiology have shown success in identifying risk factors for COPD, making this approach promising.
Where this research is happening
-
National Jewish Health
Denver, United States Active
Researchers
- Principal investigator: Cappo, James — National Jewish Health
- Study coordinator: Cappo, James
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.