Effects of Temperature Fluctuation on the Skin Barrier (K08)
Official title: Effects of Temperature Fluctuation on the Skin Barrier
Funded at National Jewish Health · NIH-11437439 · Data updated 2026-11-12
A clinician-scientist is being mentored over 5 years to understand how changes in temperature affect the skin barrier and the development of allergies in children.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | National Jewish Health NIH-funded |
| Lab location | 1 site (Denver, United States) |
| Project start | September 4, 2026 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $166,860 |
| NIH project number | 1K08AR088201-01 |
| Project ID | NIH-11437439 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and adolescents at risk of allergic diseases where skin barrier function and environmental temperature may play a role.
✕Less likely to help
Patients with allergies not related to skin barrier integrity or environmental factors may not benefit from this project.
What this research studies
This program supports Dr. Jessica Hui's development as a clinician-scientist focused on allergy and immunology. Over five years, she will study how environmental temperature changes influence the skin’s barrier function and potentially contribute to allergic sensitization. The project combines clinical insight with translational research to explore prevention or treatment strategies for allergic diseases linked to climate-related factors. Mentorship and structured training will advance her ability to conduct independent research that could inform patient care.
Why it matters
Potential benefit: If successful, the work could lead to better prevention or treatment strategies for allergic diseases influenced by environmental factors.
How similar studies have gone: Prior work in allergy and environmental factors suggests a plausible link; this project aims to translate basic insights into clinical relevance.
Where this research is happening
-
National Jewish Health
Denver, United States Active
Researchers
- Principal investigator: Hui, Jessica — National Jewish Health
- Study coordinator: Hui, Jessica
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.