Understanding how early skin problems lead to allergies in children
Official title: SUNBEAM Birth Cohort: Deciphering the role of early life skin dysfunction in development of the allergic march
Funded at National Jewish Health · NIH-11187004 · Data updated 2026-11-12
This project looks at how skin issues in babies might lead to other allergies like food allergies and asthma as they grow.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | National Jewish Health NIH-funded |
| Lab location | 1 site (Denver, United States) |
| Project start | September 6, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $1,308,830 |
| NIH project number | 5U01AI173502-02 |
| Project ID | NIH-11187004 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates would be infants and young children with eczema, as well as their families, who are interested in understanding the progression of allergic diseases.
✕Less likely to help
Patients who are adults or do not have a history of allergic diseases in early childhood may not directly benefit from this specific research.
What this research studies
Many young children experience allergic conditions like eczema, food allergies, and asthma, often in a sequence called the "allergic march." We want to understand why some babies with eczema go on to develop more allergies, while others do not. Our team believes that different types of skin inflammation in babies could explain why some are more likely to develop additional allergies. We will explore these specific skin patterns to see how they connect to the development of food allergies and asthma in early childhood.
Why it matters
Potential benefit: This work could help us identify babies at highest risk for developing multiple allergies, allowing for earlier interventions to prevent the "allergic march."
How similar studies have gone: While previous work has identified different types of skin inflammation and their link to allergies in general, this specific project explores their role in the "allergic march" progression in infants, which is largely unexplored.
Where this research is happening
-
National Jewish Health
Denver, United States Active
Researchers
- Principal investigator: Seibold, Max a — National Jewish Health
- Study coordinator: Seibold, Max a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.