Understanding how early skin problems lead to allergies in children
SUNBEAM Birth Cohort: Deciphering the role of early life skin dysfunction in development of the allergic march
['FUNDING_U01'] · NATIONAL JEWISH HEALTH · NIH-11187004
This project looks at how skin issues in babies might lead to other allergies like food allergies and asthma as they grow.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NATIONAL JEWISH HEALTH (nih funded) |
| Locations | 1 site (DENVER, UNITED STATES) |
| Trial ID | NIH-11187004 on ClinicalTrials.gov |
What this research studies
Many young children experience allergic conditions like eczema, food allergies, and asthma, often in a sequence called the "allergic march." We want to understand why some babies with eczema go on to develop more allergies, while others do not. Our team believes that different types of skin inflammation in babies could explain why some are more likely to develop additional allergies. We will explore these specific skin patterns to see how they connect to the development of food allergies and asthma in early childhood.
Who could benefit from this research
Good fit: Ideal candidates would be infants and young children with eczema, as well as their families, who are interested in understanding the progression of allergic diseases.
Not a fit: Patients who are adults or do not have a history of allergic diseases in early childhood may not directly benefit from this specific research.
Why it matters
Potential benefit: This work could help us identify babies at highest risk for developing multiple allergies, allowing for earlier interventions to prevent the "allergic march."
How similar studies have performed: While previous work has identified different types of skin inflammation and their link to allergies in general, this specific project explores their role in the "allergic march" progression in infants, which is largely unexplored.
Where this research is happening
DENVER, UNITED STATES
- NATIONAL JEWISH HEALTH — DENVER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SEIBOLD, MAX A — NATIONAL JEWISH HEALTH
- Study coordinator: SEIBOLD, MAX A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Allergic Disease