Sponsor or institution
Clinical trials and research at Beth Israel Deaconess Medical Center
As of November 12, 2026, Find a Trial lists 69 clinical trials run by Beth Israel Deaconess Medical Center that are recruiting, at sites in 3 countries (most in United States (67), South Africa (1), China (1)). By phase: Phase 2 (12), Phase 3 (4), Phase 1 (3), Phase 4 (2). There are also 508 NIH-funded research projects at this institution, with $346.4 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 69Clinical trials
- 508NIH research projects
- 3Countries
Newest trials
All recruiting trials (69)
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Daily 7-Minute Digital Meditation for Young Adults
A short daily, app-based meditation test in 18-40 year-olds in the US to see if it improves mood, stress, and well-being.
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How regular meditation relates to thinking and emotion control
This study will see if people who regularly practice Isha-style meditation differ in cognitive skills and emotion regulation compared with people who do not meditate.
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Measuring muscle health with a handheld electrical impedance device (mScan)
This project will test whether a handheld mScan device can quickly measure muscle health in adults with myopathies and in people without muscle disease by comparing its readings to MRI.
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Reverse leftover spinal numbness after knee or hip replacement with an intrathecal saline flush
This study tests whether injecting a small amount of sterile saline through a spinal catheter can quickly reduce or eliminate leftover spinal anesthesia in adults having elective lower-extremity joint replacement.
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Seeing if DCog Short on an iPad can spot neurotoxicity in CAR-T patients
This study tests whether a self-report iPad tool called DCog Short can help identify neurotoxicity in people receiving CAR-T cell therapy.
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DC/MM fusion vaccine plus BCMA CAR-T for relapsed or refractory multiple myeloma
This trial will test whether adding a personalized DC/MM fusion vaccine (with GM‑CSF) to standard BCMA CAR‑T therapy helps people with relapsed or refractory multiple myeloma.
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Personalized T-cell therapy with a DC/AML fusion vaccine plus decitabine and venetoclax for AML
This will try combining a personalized T-cell therapy and a DC/AML fusion vaccine with decitabine and venetoclax for people with newly diagnosed or relapsed AML to see if it is safe and can boost anti-leukemia immunity.
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Dry needling for pain and muscle changes in trapezius trigger points
This trial tests whether dry needling eases pain and produces measurable muscle changes (using electrical impedance myography, threshold tracking, and ultrasound) for people with trigger points in the trapezius.
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Pain relief for cervical ripening balloon during labor induction
This study tests whether applying lidocaine gel inside the vagina can reduce pain from placing a cervical ripening balloon for women undergoing labor induction.
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Roflumilast 0.3% foam for hidradenitis suppurativa
This trial tests whether applying 0.3% roflumilast foam once daily helps adults with mild-to-moderate hidradenitis suppurativa reduce painful bumps and inflammation over 16 weeks.
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Doula Link: training doulas to support perinatal mental health
This test will see if training doulas with the Doula Link program helps pregnant and postpartum people with depression or anxiety.
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Endobronchial valves with an airway blood patch for persistent air leaks
This study will try combining an airway blood patch with endobronchial valves to stop persistent air leaks in adults who cannot or do not want surgery.
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Teen Meditation Program to Boost Joy, Focus, and Resilience
This study tests whether a comprehensive meditation-and-cognitive-reframing program helps teens aged 15-18 feel more joyful, focused, and better at handling stress.
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Infrared light therapy hat for adults with drug-resistant epilepsy
This will try an infrared red-light therapy hat in adults with drug-resistant epilepsy to see if it reduces seizures and is comfortable to wear.
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Odronextamab for previously untreated low-tumor-volume advanced follicular lymphoma
This study will try odronextamab, an antibody immunotherapy, in adults with previously untreated low-tumor-volume advanced follicular lymphoma to see if it is safe and effective.
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Thopaz+ measurement of persistent air leaks after lung surgery
This pilot will test whether connecting the Thopaz+ device to chest tubes can help doctors decide if endobronchial valves will fix persistent air leaks in hospitalized adults.
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Nerve excitability testing for cisplatin-related peripheral neuropathy
This study will see if specialized nerve excitability tests (TTNCS) can detect early nerve changes in adults starting cisplatin or who recently finished cisplatin and have peripheral neuropathy.
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Perineal massage with a pelvic wand in late pregnancy
This study will try a pelvic wand for pregnant adults in late pregnancy to see if regular perineal massage changes how much control they feel during labor and birth.
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Kidney responses to exercise in heat and whether vitamin B3 changes them.
This project will test whether taking vitamin B3 changes how the kidneys respond when healthy, physically fit adults exercise in hot, humid conditions.
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Combination finasteride plus raloxifene therapy with epigenetic biomarker testing for benign prostate enlargement
This project will test whether adding raloxifene to finasteride and using epigenetic biomarker tests helps men with benign prostate enlargement who are candidates for finasteride.
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Mind-body approach for treating chronic upper extremity pain
This study is testing a mind-body program to see if it can help people with chronic upper arm and hand pain feel better and improve how well they can use their arms.
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Helping women 70+ with small, ER+ breast cancers choose the right treatment
This trial will test whether training surgeons in shared decision making and sending women 70 and older a decision aid before their first surgical visit helps them make better-informed treatment choices for small, ER+, HER2- stage I breast cancers.
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Home-delivered DASH groceries for Southeastern US residents to lower blood pressure
This project will test whether adults with high blood pressure in Florida, Georgia, and Tennessee who receive dietitian‑assisted, home‑delivered DASH groceries for 4 weeks have larger blood pressure drops than those given a shopping stipend and a DASH brochure.
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Using apixaban to treat blood clots in cancer patients with low platelet counts
This study is testing if a new dose of the blood thinner apixaban can safely help cancer patients with low platelet counts manage blood clots without causing more bleeding.
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High-definition non-invasive brain stimulation for word-finding problems after chronic traumatic brain injury
This trial tries short sessions of non-invasive high-definition transcranial direct current stimulation (HD-tDCS) to see if they help adults with long-term traumatic brain injury who have trouble finding words and remembering things.
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Remote monitoring of fetal health in high-risk pregnancies
This study is testing if women with high-risk pregnancies can safely monitor their baby's heart rate at home using a special device to see if it helps improve their care.
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Personalized dendritic cell–myeloma fusion vaccine combined with elranatamab for relapsed or refractory multiple myeloma
This will try a personalized dendritic cell–myeloma fusion vaccine given with elranatamab in people with relapsed or refractory multiple myeloma.
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Spray cryotherapy with balloon dilation for benign tracheal and subglottic stenosis
This study will test whether adding spray cryotherapy to balloon dilation reduces the need for repeat procedures in people with simple benign tracheal or subglottic stenosis compared with current standard care.
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Day‑3 (cleavage) versus day‑5–7 (blastocyst) embryo transfer for IVF patients with few embryos
This test compares whether transferring embryos on day 3 (8‑cell cleavage stage) or waiting until day 5–7 (blastocyst) leads to better pregnancy and live birth outcomes for people having their first IVF cycle who produce five or fewer embryos.
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Understanding early psychosis and its biological markers
This study is trying to find out more about early signs of psychotic disorders like schizophrenia and bipolar disorder by looking at brain scans and other health data from around 320 participants over a year.
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Saline flushing of the pleural space using a new irrigation device
This pilot tests whether flushing the pleural space with sterile saline using the CLR irrigator can help clear retained infected pleural fluid in patients who cannot receive standard intrapleural enzyme therapy.
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Sleep, Cognition, and Pain Bundle versus ERAS‑cardiac to Prevent Delirium After Heart Surgery
This trial will try a package of sleep improvement, pre-surgery brain exercises on a tablet, and 48 hours of IV acetaminophen alongside standard ERAS care to see if it lowers delirium in people 60 and older having planned heart surgery.
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Evaluating saline irrigation for treating retained pleural infections
This study is testing if adding saline irrigation to standard treatment can help people with retained pleural infections feel better and recover faster.
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Mind-body approach for treating chronic migraines
This study is testing a mind-body program to see if it can help adults with chronic migraines feel better and manage their symptoms.
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Improving sleep in older adults with mild cognitive impairment using brain stimulation and CBT-I
This trial will try combining gentle transcranial magnetic stimulation (TMS) with cognitive behavioral therapy for insomnia (CBT-I) to improve sleep in people aged 60 and older who have mild cognitive impairment or subjective cognitive decline.
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24-hour wearable blood pressure monitoring comparison
We will test if wearable cuffless and cuff-based devices can reliably measure blood pressure over 24 hours compared with a standard ambulatory cuff monitor in adults with normal or high blood pressure.
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Single-use flexible bronchoscopes for interventional pulmonology procedures
This tests whether single-use flexible bronchoscopes are safe and work well for adults undergoing routine diagnostic or therapeutic bronchoscopic procedures.
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Understanding how to treat individuals at high risk for psychosis
This study is testing different treatments, like brain stimulation and mindfulness techniques, to see if they can help people who are at high risk of developing psychosis.
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Using epcoritamab to treat previously treated Waldenstrom Macroglobulinemia
This study is testing if a new treatment called epcoritamab can help people with Waldenstrom Macroglobulinemia who have already received other treatments.
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Epcoritamab treatment for patients with follicular lymphoma not responding to initial therapy
This study is testing if a new treatment called epcoritamab can help people with follicular lymphoma who didn't respond well to their first therapy.
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Rituximab plus venetoclax as first treatment for marginal zone lymphoma
This trial will test whether combining rituximab and venetoclax helps adults with previously untreated marginal zone lymphoma.
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Using Electrical Impedance Myography to Track ALS Progression
This study is testing if a new method using Electrical Impedance Myography can help track how ALS progresses in patients to improve future treatments.
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General screening for volunteers in infectious disease studies
This study is looking for healthy adults to volunteer for upcoming vaccine and treatment trials by checking if they meet the necessary health criteria.
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Effects of pregnenolone on depression in menopausal women
This study is testing if a dietary supplement called pregnenolone can help reduce depression in menopausal women by boosting a hormone that may be low during this time.
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Understanding TB Infection Risks in Health Workers
This study is trying to understand how health workers in Cape Town respond to tuberculosis infections over a year to find better ways to protect them from getting sick.
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Monitoring brain health during non-cardiac surgery in older patients
This study looks at the best blood pressure levels to keep during non-heart surgeries for older patients to help protect their brain health.
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Comparing precision ventilation to standard care for ARDS
This study tests if a personalized breathing method can help people with Acute Respiratory Distress Syndrome survive better than the usual care they receive.
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Mind-body intervention for people with Long COVID
This study is testing a mind-body program to see if it can help people with Long COVID feel better and improve their daily activities.
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Exploring heart health in postmenopausal women
This study looks at how changes in estrogen levels may affect heart health in postmenopausal women and could lead to heart failure.
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Promoting physical activity in patients with COPD and heart failure
This study is testing if a new program called Mindful Steps can help people with COPD and heart failure be more active by tracking their daily steps for a year.
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Registry for Alzheimer's Disease Treatment with Monoclonal Antibodies
This study is creating a registry to see if a new treatment for Alzheimer's disease can help people with early symptoms feel better and slow down their decline.
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Using self-adjusted nitrous oxide to manage pain and anxiety during vasectomy
This study is testing if letting patients control their nitrous oxide levels during a vasectomy can help reduce their pain and anxiety.
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Combination treatment for advanced bile duct cancer
This study is testing a new combination treatment for patients with advanced bile duct cancer that can't be surgically removed to see if it helps them feel better and live longer.
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Assessing the significance of severe coronary artery blockages before PCI
This study is testing if a new way of measuring blood flow can help doctors better understand the impact of severe blockages in heart arteries before and after a procedure called PCI.
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Investigating how sleep loss affects emotion regulation
This study is testing how losing sleep for three nights affects people's ability to handle their emotions compared to those with insomnia and healthy individuals.
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Microwave ablation for treating lung cancer nodules
This study is testing a new microwave treatment for destroying small lung cancer nodules to see if it is safe and effective for patients.
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Lung surgery for patients with severe emphysema who didn't improve with bronchoscopic treatment
This study is testing a new lung surgery for people with severe emphysema who didn't get better from other treatments to see if it can help them breathe easier and improve their quality of life.
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Mapping lymphatic drainage pathways in women with breast cancer
This study is trying to see if differences in lymphatic pathways in healthy women and breast cancer survivors can help predict who might develop lymphedema after treatment.
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Using hydrocortisone to treat severe acute pancreatitis
This study is testing if giving hydrocortisone to people with severe acute pancreatitis can help them recover faster and spend less time in the hospital.
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Screening for pancreatic cancer in high-risk individuals
This study is testing if screening for pancreatic cancer helps high-risk individuals catch the disease early and improve their chances of successful treatment.
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Lung volume reduction using a new approach for emphysema treatment
This study is testing a new surgery method that combines fixing lung fissures and placing valves to see if it helps people with severe emphysema feel better compared to regular treatments.
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Endovascular repair for complex aortic conditions using modified grafts
This study is testing a new type of graft to see if it can safely and effectively repair complex aortic problems in high-risk patients who can't have traditional surgery.
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Evaluating the effects of sleep apnea on multiple sclerosis
This study looks at how sleep apnea affects people with multiple sclerosis to see if it makes their symptoms worse.
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Mapping human brown fat to understand metabolism
This study is trying to learn more about the differences between brown and white fat in people to see how they affect metabolism and help with conditions like type 2 diabetes.
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Gastric emptying in women in early labor with different drinks
This study tests how quickly the stomach empties in women in early labor after drinking water or a sports drink, while also looking at their hunger levels and whether they received epidural pain relief.
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Using CPAP to improve walking distance in patients with airway collapse
This study is testing if using a CPAP machine can help people with airway collapse walk farther in six minutes.
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Evaluating statin use after brain hemorrhage
This study is testing whether people who have had a brain bleed should keep taking their statin medications to see if it helps prevent more brain bleeds and other serious health problems.
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Evaluating biomarkers for infection and inflammation in sepsis
This study is testing new blood markers to see if they can help doctors identify patients with sepsis who are at risk for serious problems, so they can provide better care.
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Comparing ultrasound guided and traditional hematoma blocks for pain relief in wrist fractures
This study tests whether using ultrasound to guide pain relief injections can work better for adults with wrist fractures than the traditional method.
NIH-funded research (newest 40 of 508)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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SATURN MRI ancillary study: statins after intracerebral hemorrhage and brain MRI markers
This study looks at what happens to brain MRI markers and health outcomes when people with a specific type of brain bleed continue or stop taking statins.
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Statin use after brain bleed MRI study in ICH patients (SATURN MRI) Ancillary Study
This project tests whether continuing or stopping statin therapy after an intracerebral hemorrhage affects brain changes seen on MRI and related health outcomes in people with lobar ICH.
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Statin use after brain bleed: SATURN MRI ancillary study
This project tests whether continuing statin medicines after a brain bleed (lobar intracerebral hemorrhage) affects new brain blood vessel findings and long-term health.
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XenCAT: Single Cell Atlas for Xenopus
Aims to map gene activity at the single-cell level in Xenopus to help understand how cells develop and how this relates to human disease.
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Statin use after lobar intracerebral hemorrhage
This trial compares continuing versus stopping statins in people who had a lobar intracerebral hemorrhage to see how that affects repeat brain bleeds, strokes, heart attacks, and recovery over two years.
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Statin use after lobar brain hemorrhage
This trial compares stopping versus continuing statin medicine in people who had a lobar brain bleed to learn effects on repeat bleeding and future heart or stroke events.
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Minimally Invasive Sampling to Improve HIV-Associated M meningitis Diagnosis in Africa
A research study is testing easier, less invasive ways to diagnose meningitis in people living with HIV, with a focus on making diagnosis faster and more accurate in Africa and the US.
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Immunotherapy for Cure: advancing HIV remission and eradication
A large, multi-year program will explore immune-based strategies to achieve long-term HIV control without daily ART, with input from researchers, industry, government, and the community.
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Lateral hypothalamic neurotensin neurons and narcolepsy symptoms
Aims to see if activating specific brain cells in the lateral hypothalamus can reduce sleepiness and cataplexy in narcolepsy models.
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How the uterus drains fluid and supports pregnancy
Researchers will map how lymphatic vessels in the uterus grow and work during pregnancy and when not pregnant to help people with pregnancy-related and other uterine health issues.
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Allopregnanolone and mood in perimenopause: how it may help women through hormonal transitions
A study tests whether the natural hormone allopregnanolone can improve mood and brain biology for women going through perimenopause.
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CAB-LA PrEP for breastfeeding women after delivery in Botswana
This study tests a long-acting HIV prevention shot for new mothers who are breastfeeding in Botswana to see if it prevents HIV safely and effectively.
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Why some human brains age faster
This project looks at genes and tiny RNA molecules in brain samples to find what causes normal and faster-than-normal brain aging, including links to respiratory infections like COVID-19.
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Better TB testing for health workers
This project will use frequent blood tests and new immune assays in healthcare workers in Cape Town to spot recent tuberculosis infection and track immune changes over time.
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Understanding how NFATc1 dysregulation affects lymphatic health and brain fluid drainage
This grant studies how a specific cellular switch (NFATc1) goes haywire in lymphatic vessels and uses Down syndrome as a model to find ways to improve brain fluid drainage.
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Structure-guided design of apramycin analogs to overcome resistance and boost effectiveness
A study to create and test new apramycin-like molecules aimed at treating hard-to-kill bacteria such as Acinetobacter baumannii and other gram-negative pathogens.
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Brain circuits linked to dangerous fentanyl-xylazine combo and new reversal strategies
Aimed at understanding why fentanyl mixed with xylazine causes deadly breathing and body-cooling problems, and finding new ways to reverse these effects.
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Impact of Diet on Symptoms in Hereditary Alpha-Tryptasemia
This study looks at how food and diet affect people with hereditary alpha-tryptasemia and related gut symptoms.
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Neural signals behind nighttime bathroom trips in older adults
A study investigates how brain signals related to arousal affect nightly bathroom trips in older adults, with a focus on bladder control and sleep disruption.
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Meningeal pain and migraine brain hyperexcitability in people
A short study in adults with migraine to understand how pain signals from the brain coverings might make the visual cortex more excitable and trigger migraines.
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Glycan signals in neutrophils and pneumonia risk after brain injury
This grant explores how immune Cells in people with brain injury may become more prone to pneumonia due to changes in sugars on their cells, with the goal of preventing infections.
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Piezo1’s role in blood clotting across vessels
Researchers are exploring how a tiny sensor in blood vessels called Piezo1 influences clot formation, with the aim of reducing clotting risks without causing dangerous bleeding.
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Novel three-antigen TB vaccine to boost protection in adults
A new vaccine approach for TB in adults aims to improve protection by combining three specific TB antigens with an immune-boosting adjuvant.
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How the lymphatic system changes after axillary lymph node removal in breast cancer
This project looks at why some breast cancer patients develop lymphedema after sentinel or axillary lymph node removal and how the lymphatic system’s structure affects that risk.
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Myeloid-derived suppressor cells in alcohol-associated liver disease
A doctor-scientist team is studying a specific type of immune cell, MDSCs, to see if they help explain why alcohol-related liver disease makes infections and liver failure more likely.
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Elastin-like particles to deliver gene therapies for cystic fibrosis
A new nanoparticle system is being developed to deliver genetic therapies directly to the lungs of people with cystic fibrosis, including those with nonsense mutations.
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How the brain controls hunger and fullness through a key brain hub
A study at a major hospital is exploring how the brain tells you when you’re hungry or full by tracing signals through a brain area called the parabrachial nucleus.
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How ROCK1 and ROCK2 help beta cells release insulin
This grant studies how two proteins called ROCK1 and ROCK2 control insulin release from pancreatic beta cells in adults with type 2 diabetes.
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Lymphoid follicles on a chip to study aging-related immune dysfunction
A patient-centered look at how aging changes our immune system, using a human lymphoid tissue on a chip to model aging and immune responses.
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Harnessing copper to tackle chemoresistant ovarian cancer
A new approach uses copper-triggered cell death to target high-grade serous ovarian cancer that stops responding to standard chemotherapy.
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Or olive-oil derived compound to prevent bone loss in women
A safe, orally taken nutraceutical may help prevent osteoporosis in adult women by supporting bone formation and reducing bone loss.
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Suburothelial myofibroblasts in aging bladder
A study of how a specific bladder cell type changes with age and may contribute to common bladder symptoms in older adults.
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DNAJC22: a new target to treat fatty liver disease
A physician-scientist-led project will explore how the gene DNAJC22 affects fat buildup in liver cells and test whether turning this gene off could be a new way to treat MASLD.
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Molecular clues to daily blood pressure changes and heart disease
Researchers are exploring how dynamic blood pressure changes throughout daily life relate to heart disease, with new protein measurements to identify potential targets for better control.
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Leptin Gateway: How the Brain Gets Its Signal
This grant studies how the hormone leptin moves from the bloodstream into the brain, to understand why obesity can blunt its effects.
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Glycan tools and technologies to study sugars in health and disease
A renewal project at a major medical center that develops and shares glycan-based technologies to help researchers understand how sugars on proteins and lipids influence health and disease.
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Kidney Cancer Career Enhancement Program (CEP) at DF/HCC
A career-boosting program supports junior investigators studying kidney cancer to help them advance in basic, translational, and clinical work.
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Kidney Cancer Development Program at DF/HCC
A funded program at Dana-Farber/Brigham and Women’s Kidney Cancer Center supports new ideas from researchers to improve understanding and treatment of kidney cancer.
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Personalized antigens for kidney cancer therapy
This grant explores identifying and targeting tumor-specific antigens in kidney cancer to develop more effective, personalized immunotherapies.
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Optimizing Anti-PD1 Therapy for High-Risk and Metastatic Kidney Cancer
A large cancer research grant is testing how best to use anti-PD-1 therapy to help people with high-risk and metastatic kidney cancer live longer and with fewer side effects.
Quick answers
How many clinical trials run by Beth Israel Deaconess Medical Center are recruiting right now?
69, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (67 trials), South Africa (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 12, Phase 3: 4, Phase 1: 3, Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.