Evaluating the effects of sleep apnea on multiple sclerosis
Official title: Prevalence and Impact of Obstructive Sleep Apnea in Multiple Sclerosis
Run by Beth Israel Deaconess Medical Center · NCT04603196 · Data updated 2026-11-12
This study looks at how sleep apnea affects people with multiple sclerosis to see if it makes their symptoms worse.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 800 (estimated) |
| Sponsor | Beth Israel Deaconess Medical Center Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Status | Recruiting |
| Started | June 20, 2019 |
| Main results expected | June 20, 2026 |
| Study ends | June 20, 2030 |
| Registry record updated | May 11, 2026 |
| Trial ID | NCT04603196 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old with a confirmed diagnosis of multiple sclerosis.
✕Probably not a fit
Patients who cannot provide informed consent or do not have a diagnosis of multiple sclerosis will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess how obstructive sleep apnea (OSA) influences the clinical and radiological features of multiple sclerosis (MS). Researchers will collect and analyze clinical data, including MRI results, lab tests, medical history, and sleep studies from MS patients. The study specifically investigates the correlation between the presence of sleep apnea and the severity of MS, focusing on potential impacts on neuron and axon health. By understanding these relationships, the study seeks to shed light on the detrimental effects of sleep apnea on MS progression.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for MS patients by addressing sleep apnea and its effects on disease progression.
How similar studies have gone: While the relationship between sleep apnea and multiple sclerosis has been noted, this specific investigation into their correlation is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Written consent * Over age 18 * Confirmed diagnosis of multiple sclerosis Exclusion Criteria: * cannot provide informed consent
Where it's running
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States Recruiting
Study contacts
- Study coordinator: Jacob A Sloane, MD, PhD
- Email: jsloane@bidmc.harvard.edu
- Phone: 6176673726
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.