Evaluating the effects of sleep apnea on multiple sclerosis

Prevalence and Impact of Obstructive Sleep Apnea in Multiple Sclerosis

Observational Beth Israel Deaconess Medical Center · NCT04603196

This study looks at how sleep apnea affects people with multiple sclerosis to see if it makes their symptoms worse.

Quick facts

Study typeObservational
Enrollment800 (estimated)
Ages18 Years and up
SexAll
SponsorBeth Israel Deaconess Medical Center Academic / other
Locations1 site (Boston, Massachusetts)
Trial IDNCT04603196 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess how obstructive sleep apnea (OSA) influences the clinical and radiological features of multiple sclerosis (MS). Researchers will collect and analyze clinical data, including MRI results, lab tests, medical history, and sleep studies from MS patients. The study specifically investigates the correlation between the presence of sleep apnea and the severity of MS, focusing on potential impacts on neuron and axon health. By understanding these relationships, the study seeks to shed light on the detrimental effects of sleep apnea on MS progression.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old with a confirmed diagnosis of multiple sclerosis.

Not a fit: Patients who cannot provide informed consent or do not have a diagnosis of multiple sclerosis will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for MS patients by addressing sleep apnea and its effects on disease progression.

How similar studies have performed: While the relationship between sleep apnea and multiple sclerosis has been noted, this specific investigation into their correlation is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Written consent
* Over age 18
* Confirmed diagnosis of multiple sclerosis

Exclusion Criteria:

* cannot provide informed consent

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Multiple SclerosisObstructive Sleep Apnea
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.