Condition
Suicide clinical trials and research
As of November 12, 2026, Find a Trial lists 61 Suicide clinical trials that are recruiting, at sites in 10 countries (most in United States (42), Canada (4), Spain (3)). 1 was first registered in the last 30 days. By phase: Phase 2 (5), Phase 1 (2), Phase 1/2 (1), Phase 2/3 (1). The most active sponsors are VA Office of Research and Development (3), Massachusetts General Hospital (3), Unity Health Toronto (3). There are also 388 NIH-funded research projects on Suicide, with $214.9 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 61Clinical trials
- 388NIH research projects
- 1New in 30 days
- 10Countries
Newest Suicide clinical trials
All recruiting trials (61)
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Friends and family training for those at risk of suicide
A six-week program tests whether training for caregivers can help them support a loved one at risk of suicide while also taking care of their own mental health.
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Inhaled DMT for major depressive disorder
This trial tests whether inhaled DMT can quickly ease depressive symptoms and reduce suicide risk in adults with major depressive disorder.
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Suicide risk and learned suicide ability in people with mood disorders
This project will try to identify which biological, psychological, social, and clinical factors relate to suicide risk and the learned ability for suicide in people aged 16–60 with mood disorders by collecting blood, urine, and questionnaire data.
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Combining the Youth-Nominated Support Team with CBT for Black adolescents at acute suicide risk
This project will test whether adding a computer-assisted Youth-Nominated Support Team to Cognitive Behavioral Therapy for Suicide Prevention helps Black adolescents (ages 12-17) who come to an urban emergency setting with suicidal thoughts or self-injury.
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Remote case management to prevent suicide after psychiatric hospital discharge
This project will test whether a 6-month remote program called Pathfinding helps active-duty Army soldiers reduce suicidal behavior after leaving inpatient psychiatric care.
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Text reminders to help parents keep teens safe after a suicide-related ED visit
This study tests whether sending parents text messages can help them reduce their teen’s access to lethal means and increase safety practices after a suicide-related emergency visit.
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Suicide prevention in primary care clinics in Nepal
This project will try a package of tools and training to help primary care providers in Bagmati Province, Nepal, better find and manage patients at risk of suicide.
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Just-in-time Safety Planning for suicidal youths using ViraSafe
This study tests whether the ViraSafe app, an enhanced version of the BRITE safety planning tool, helps suicidal youths engage with coping skills and safety planning more than the original app.
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Sleep and circadian interventions for college students at high risk of suicide
Three sleep-focused approaches are being tested to see if they can help reduce suicidal thoughts and depression in high-risk college students receiving psychiatric care.
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Co-creating suicide prevention tools for people in prison
This project will work with people in prison and prison care staff to test and adapt three suicide prevention tools so they fit prison life and are easier to use.
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Youth Empowerment and Safety program for sexual and gender minority teens
This project will try Peer Support Specialist (PSS) services to see if they help sexual and gender minority youth ages 12–17 who are involved with juvenile justice, child welfare, or community mental health and who have experienced self-harm or suicidal thoughts.
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Chat conversations with the suicide helpline 1813: how people experience them
This study tests how people feel before and after chatting with the Zelfmoordlijn 1813 helpline to see if the chat affects suicidal thoughts or feelings.
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Comparing ASSIP and ACT to reduce suicidal thoughts after a recent suicide attempt
This project will try ASSIP and ACT alongside usual care to see which better lowers suicidal thoughts and mental pain in adults who recently attempted suicide.
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Culturally adapted suicide prevention for Black middle school students in Chicago
This pilot will try a culturally adapted Signs of Suicide program to see if it helps Black middle school students in Chicago recognize suicidal thoughts and get help.
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Sleep and bright-light program for teens with depression and sleep problems
This project will try a sleep-and-bright-light program to improve sleep and mood in teens aged 12–18 with moderate-to-severe depression and clinically significant sleep problems who are at risk for suicidal thoughts.
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Attempted Suicide Short Intervention Program for Older Adults (ASSIP-OA) for people aged 65 and up
This randomized study will test whether a version of the ASSIP counseling program adapted for people aged 65 and older reduces repeat suicide attempts and ongoing suicidal thoughts compared with usual care.
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Evaluating a suicide risk screening program in rural schools
This study is testing a new program in rural West Virginia schools to see if it can help identify and support students at risk of suicide.
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RomSi mobile app to reduce suicide stigma and boost help-seeking
This project tests the RomSi mobile app to see if it reduces suicide stigma and encourages help-seeking among Spanish-speaking adults, with tailored content for people with low suicidal thoughts and for relatives or friends bereaved by suicide.
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Examining skills and coping in teens' daily lives
This study is testing two different skills to see which helps teens who have hurt themselves feel better and cope with stress in their daily lives.
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Text-message support for parents after their teen's ER visit for suicide risk
This program tests whether sending adaptive text messages to parents can help adolescents (ages 13–17) who come to the emergency room with recent suicidal thoughts or attempts.
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Mobile program to reduce suicidal thoughts in Veterans.
This pilot will try a brief mobile program called MIST to reduce harmful suicidal beliefs and thoughts in Veterans with recent suicidal ideation.
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Brief Skills for Safer Living: one-session therapy for people with suicidal thoughts
This trial will test whether one brief, virtual Brief-SfSL session plus usual care helps adults in Canada with recent suicidal thoughts reduce suicidal thinking compared with usual care alone.
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Support for Suicide Intervention Officers in the Army National Guard
This study is testing whether extra training or a supportive community helps Suicide Intervention Officers in the Army National Guard better prevent suicide among soldiers.
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Testing a new drug for treatment-resistant depression
This study is testing a new drug called HNK to see if it can help people with treatment-resistant depression feel better when other medications haven't worked.
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Intensive Crisis Intervention for teens with suicidal thoughts or behaviors
This project will try a brief, family-focused Intensive Crisis Intervention to see if it helps 12–17-year-olds with suicidal thoughts or recent attempts reduce suicidal behavior and avoid inpatient psychiatric care.
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Understanding the impact of mood disorders and treatment responses
This study is trying to learn more about how people with depression and bipolar disorder respond to treatment by talking to them weekly for up to 12 weeks to improve future care and predict how well medications might work.
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Monitoring suicide risk in adolescents using biometric data
This study is testing whether using data from wearable devices can help spot rising suicide risk in teenagers so that they can get help before a crisis happens.
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Warrior CARE: Cannabis Behavioral Health
This study tests whether different cannabis compounds (THC, CBD, or THC+CBD) or placebo can help veterans with PTSD and suicidal thoughts over 12 weeks.
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Online cognitive behavioral therapy for preventing suicide and treating depression
This study is testing two online therapy courses for veterans to see if they can help with depression and suicidal thoughts.
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Gamified mHealth program to reduce post-discharge suicide risk
This project tests whether a gamified mobile app (TEEM) can help recently discharged adults with mental disorders in Shenzhen reduce suicidal thoughts and behaviors.
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Caring Connections: youth suicide detection and support
This pilot will test whether Caring Connections, a culturally adapted 90-day care coordination program delivered through community and faith-based hubs, helps high-risk Black and other youth aged 13–19 reduce suicidal thoughts and connect with mental health services.
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Digital peer-support program using recovery stories for suicidal adolescents
The team will try a brief, low-cost digital program that shares short recovery stories to see if it reduces suicidal thoughts in ethnically diverse teens in The Bronx.
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Brief problem-solving program in person, by conference call, or via smartphone to prevent suicide in adults over 50
This project will test whether a short problem-solving program delivered in person, by conference call, or through a smartphone app can reduce suicidal thoughts in people aged 50 and older who live in Galicia, Spain.
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Examining suicide risk and resilience in older adults after losing a spouse
This study is trying to see how sleep and social activities affect mood and thoughts about suicide in older adults who have recently lost a spouse, while also testing a program to help them take care of themselves and create stable daily routines.
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Preventing suicidal behavior in high-risk youth in emergency care settings
This study is testing two different short interventions to see which one better helps young people aged 12-19 who are at risk of suicide when they come to the emergency room.
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Using ketamine to help suicidal patients in the emergency department
This study is testing if a low dose of ketamine can safely help people in the emergency department who are feeling suicidal by reducing their symptoms and possibly shortening their hospital stay.
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Comparing psychotherapy treatments for suicide risk in Veterans
This study is testing two different therapy options for Veterans who have been hospitalized for suicide risk to see which one helps them cope better and reduces their suicidal thoughts.
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A digital platform to reduce suicide risk in at-risk youth
This study is testing a new digital platform called Vira to see if it can help reduce suicide risk in teens aged 13-18 who are getting treatment for mental health issues.
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Assessing suicide risk using implicit and explicit methods
This study is testing a computer tool to see how hidden thoughts about suicide change over time in people who have or haven't thought about suicide openly or tried to harm themselves.
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Mobile app for teens and parents to reduce substance use
A teen-focused mobile app plus parent support is being tested to see if it helps teens reduce substance use and improve related mental health, with or without extra parent support, compared to receiving online resources.
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Reducing suicide risk among sexual and gender diverse young adults in Texas
This study is testing two different suicide prevention programs to see which one helps young adults aged 18-24 from sexual and gender diverse backgrounds in Texas feel safer and reduce their risk of suicide.
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Enhanced Outreach After ED Visit to Prevent Suicide Attempts
This study tests a weekly outreach program by a crisis organization after an ED visit for suicidal thoughts to see if it’s doable and helpful for participants.
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Interventions to reduce short-term suicide risk after hospitalization
This study is testing new ways to help adults who were recently hospitalized for suicidal thoughts by using their smartphones to check in on their feelings and provide support when they need it.
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Exploring the link between eco-anxiety and suicide risk in adolescents
This study is trying to see if feelings of eco-anxiety are linked to a higher risk of suicide in teenagers aged 12 to 16 who are hospitalized for mental health issues.
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Using ketamine and a crisis response plan to help suicidal patients in the emergency department
This study is testing whether a single dose of ketamine along with a crisis response plan can help adults in the emergency department who are having suicidal thoughts feel better compared to regular care.
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Using a decision support system to prevent suicide attempts in emergency patients
This study tests whether giving doctors special risk scores about patients' chances of attempting suicide can help prevent those attempts in people coming to the emergency room with mental health issues.
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New treatment method for reducing suicidality after a crisis
This study is testing a new short-term treatment for people who have recently tried to harm themselves to see if it can help reduce feelings of hopelessness and improve support from family and friends.
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Integrated suicide and trauma therapy for adults with childhood trauma and suicidal thoughts
This pilot will test a 12-week program that combines brief safety and coping skills with trauma-focused therapy to reduce suicide risk in adults who have a history of childhood trauma and current suicidal thoughts.
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Scaling up e-Connect in Juvenile Probation Settings
This project tests a plan to expand e-Connect, an evidence-based suicide risk and cross-system linkage program, across nine Indiana counties to see if it can be adopted widely and cost-effectively in juvenile probation settings.
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Examining brain connectivity in suicidal opioid users
This study is trying to see if a brain stimulation treatment can help reduce cravings and suicidal thoughts in people who use opioids.
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Reducing suicide risk in people with psychosis by targeting emotion regulation
This study is testing a new therapy aimed at helping people with psychosis manage their emotions better to reduce their risk of suicide.
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Identifying biomarkers for depression and suicide in adolescents
This study is trying to find specific markers in the body that can help understand depression and suicidal thoughts in teenagers, while also looking at how standard treatments affect these issues.
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Improving mental health for Hispanic adolescents in primary care
This study is testing a new online program called Familias Unidas to see if it can help Hispanic teens aged 12 to 16 feel less depressed, anxious, and suicidal while getting support from their families.
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Comparing emergency care approaches for youth suicide prevention
This study tests whether providing emergency care alone or adding follow-up support helps young people aged 13-24 who come to the hospital with suicidal thoughts feel better and stay engaged in mental health treatment.
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Testing a mobile app to help prevent suicide
This study is testing a new mobile app designed to help young adults who have had suicidal thoughts or behaviors in the past month to see if it can prevent suicide.
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Smartphone-based Ecological Momentary Intervention to Help Prevent Suicide
A smartphone-based program called SmartSafe is tested to see if it can help prevent suicidal thoughts and behaviors in people recently at risk, alongside usual care.
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Recovery-focused therapy for Veterans after suicidal episodes
This study is testing a new therapy for Veterans who have recently had suicidal thoughts to see if it helps them recover and improve their mental health.
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ELIOS online referral and support for young people with suicidal thoughts
This project will test whether ELIOS, an online web-clinician contact system, can reduce suicidal thoughts in French adolescents and young adults who seek help online.
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A service system intervention for youth at risk of suicide
This study is testing a new program to help young people on probation who are at risk of suicide by connecting them with the right support and resources.
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Registry for improving mental health care in the Maritimes
This study is trying to improve mental health care for people with depression in the Maritimes by creating a registry that helps track treatments and outcomes while involving those who have experienced these challenges.
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Support for distressed medical residents and faculty
This study is testing an anonymous online tool to help medical residents and faculty at Oregon Health and Science University check in on their mental health and encourage them to seek help if they need it.
NIH-funded research (newest 40 of 388)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Understanding Invisible Suicide Risks in Youth: A National Study in Guyana
A nationwide study in Guyana aims to learn about hidden factors that contribute to suicide risk among young people so we can prevent tragedy.
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Mobile safety planning for at-risk young adults
A digital, text-based safety planning program for young adults (ages 18–24) to help prevent suicide and stay connected to support.
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Reducing firearm suicide among Veterans with peer-delivered counseling
A VA-funded project tests whether peer-delivered counseling helps Veterans store firearms more securely and reduces suicide risk.
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How School Cellphone Rules Might Affect Youth Suicide and Violence
A study will look at whether restricting students’ use of cellphones at school influences rates of suicidal thoughts and interpersonal violence among youth.
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INCLUSAVE: helping young adults with IDD access suicide-prevention trainings
A new NIH grant studies whether two proven gatekeeper trainings (ASIST and safeTALK) can be delivered in inclusive settings to support young adults with intellectual and developmental disabilities and their communities.
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A universal school program to help middle schoolers stay emotionally regulated and safer
A school-based program teaches students calming skills to reduce violence and thoughts of self-harm, tested in a randomized trial with middle schoolers.
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Technology-assisted suicide prevention for youth in Colombian school settings
A youth-focused program will test a culturally tailored digital platform and teacher training to reduce suicidal thoughts and behaviors in schools.
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Preventing Suicide Among Teens Who Use Substances in School Settings
Aims to see if how schools respond to substance-use incidents (like alcohol or drugs) can lower suicide risk among high‑risk students.
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Diversifying Genetic Data on Suicide Death in India and Beyond
Aimed at collecting diverse genetic and phenotypic data from suicide deaths to improve understanding and prevention for populations that are currently underrepresented.
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Peer-delivered, family-engaged brief interventions to prevent youth suicide in Nepal
A pilot program in Nepal tests a teen-friendly, low-cost plan to use peers and family support to prevent suicide among youth aged 12–24.
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Peer-delivered and family-supported brief interventions to prevent youth suicide in Nepal
A pilot program in Nepal tests brief, youth-friendly interventions delivered by peers and supported by families to reduce suicide risk among 12–24 year-olds.
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Qnnections: A Social Connection‑Focused Suicide Prevention for LGBTQ+ Veterans
A new group-based program tailored for LGBTQ+ Veterans aims to strengthen belonging and reduce burdensomeness to help prevent suicide.
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Nurse- and Peer-Led Suicide Prevention for Women in Tajikistan
A nurse- and peer-led program in Tajikistan aims to help women at risk of suicide by adding tailored, frontline support in primary care.
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Targeted online suicide prevention for Veterans
A web-based, one-session intervention for Veterans to reduce thoughts of suicide and self-harm by helping them manage distress and rigid thinking.
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Telehealth support to prevent suicide in people with alcohol use disorder in Tanzania
A telehealth counseling program is being adapted to help reduce suicide risk for people with alcohol use disorder in emergency departments in Tanzania.
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Treatment for Relationships and Safety Together (TR&ST): couples therapy to reduce suicide risk
A couples-based therapy to help veterans with suicidal thoughts by strengthening relationship support and safety between partners.
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Suicide prevention support in rural Nepal primary care
This project brings practical suicide-prevention supports to primary care clinics and community health workers in rural Nepal to help people who are at risk.
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Uncovering the genetics and biology of suicide outcomes
Researchers are studying the genetic and biological factors behind suicide outcomes to better understand why they occur and how they relate to mental health conditions.
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Scaling Out S.A.F.E. Firearm Across Two Health Systems as a Universal Suicide Prevention Strategy
A proven firearm-safety intervention used during well-child and adult visits would be expanded across two large health systems to help prevent suicide.
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Suicide prevention using safety plans and cognitive behavioral therapy for adolescents in Mozambique
Young people in Mozambican secondary schools will receive safety planning and cognitive behavioral therapy from trained non-specialists to help reduce suicidal thoughts and behaviors.
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Understanding how social connection affects suicide risk during the college transition
A study following college-bound teens and young adults to see how online and offline friends, messages, and everyday life details influence thoughts of suicide.
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THRIVE: a recovery-focused suicide prevention program for crisis stabilization centers
A multi-site plan tests a brief recovery-oriented therapy and post-discharge coaching to reduce suicide risk for adults treated in crisis stabilization centers.
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Understanding how people use the 988 Suicide & Crisis Lifeline and what they plan to do next
This project studies how distressed adults experience the 988 Lifeline and what they expect or intend to do after contacting it.
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Pediatric Emergency Department Family Navigation to Connect Youth with Suicide and Self-Injury Care
A program helps families navigate emergency department visits for youth with suicide- or self-injury-related concerns to connect them with mental health care.
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INSPIRE: Innovations in Suicide Prevention Research
Aims to improve suicide prevention by creating linked data systems and benchmarks to help insurers, health systems, and correctional departments monitor and prevent suicides.
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A home-based STEP-Home workshop to help recently transitioning Veterans stay connected and safer
A pilot program using video-based STEP-Home workshops to help recently transitioning Veterans reintegrate, stay engaged with care, and reduce suicide risk.
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Center to speed up real-world youth suicide prevention
A nationwide effort to put proven youth suicide prevention strategies into everyday health care so that at-risk kids get help faster.
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Coordinating Suicide Prevention Across Jails and Community Health
A large national effort to better identify and connect people at risk of suicide who touch both jail systems and community healthcare to get faster, safer care.
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Centering suicide prevention at the intersection of health and criminal-legal systems
A large NIH-funded center is testing how data from police and court interactions can help identify people at risk of suicide and connect them with care.
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Peer-delivered and family-engaged brief interventions to prevent youth suicide in Nepal
A pilot program in Nepal tests a low-cost, peer-led package plus family involvement to help 12–24 year-olds stay safe and connected when at risk of suicide.
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Preteen Suicide Risk: Data Coordinating Center
A national project creates a central data hub to support six youth suicide research studies, so clinicians and families can better understand risk and protective factors for children aged 8–12.
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Technology-assisted suicide prevention for youth in Colombian schools
A youth-focused, culturally tailored program uses digital tools and teacher training to reduce suicidal thoughts and behaviors among adolescents in schools.
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Answering the Alarm: A Care System to Help Black Youth at Risk for Suicide
A program to help Black kids who come to the emergency department be identified early, get connected to mental health care, and stay in treatment to reduce thoughts of suicide and self-harm.
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Understanding how suicide risk spreads on social media among young adults
This project studies how suicidal thoughts and behaviors may spread online among 18–25-year-olds using Twitter/X and Reddit, with real-time data and smart devices.
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Safer stem cell therapy for diabetes using controllable, expandable islet-like cells
A new stem cell–based treatment aims to replace damaged pancreatic cells to help people with diabetes control their blood sugar without lifelong immune drugs.
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How alcohol use and suicide risk relate in daily life after AUD treatment
A study follows people after residential alcohol treatment to understand how moment-to-moment drinking and suicide risk are connected and how digital tools can help prevent crises.
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Inflammation and autoimmune disease in relation to suicide risk in Veterans
This project looks at whether inflammatory markers and autoimmune diseases are linked to thoughts and acts of suicide among veterans.
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Intensive outpatient programs to reduce suicide risk after hospital discharge for Medicaid patients
A program that uses short-term intensive outpatient care after discharge to help Medicaid patients stay safe and lower the chance of a suicide attempt or death.
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Strengths-based suicide prevention for Black sexual minority youth
A research project aims to help Black sexual minority youth reduce suicidal thoughts and behaviors by understanding protective factors and risks in everyday life.
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Sleep and suicide risk after psychiatric hospital discharge in Veterans
This project follows Veterans after psychiatric hospitalization and tracks sleep with a wearable and daily smartphone prompts to link sleep patterns with suicidal thoughts and behaviors.
Related topics
Quick answers
How many Suicide clinical trials are recruiting right now?
61, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 10 countries. The most sites are in United States (42 trials), Canada (4 trials), Spain (3 trials), France (3 trials), Belgium (3 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 5, Phase 1: 2, Phase 1/2: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.